ClinVar Miner

List of variants in gene MSH2 reported as likely benign for not provided

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Gene type:
ClinVar version:
Total variants: 246
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HGVS dbSNP gnomAD frequency
NM_000251.3(MSH2):c.792+282T>C rs17224199 0.02331
NM_000251.3(MSH2):c.380A>G (p.Asn127Ser) rs17217772 0.02317
NM_000251.3(MSH2):c.942+4A>T rs749778569 0.02181
NM_000251.3(MSH2):c.1386+104C>T rs17224444 0.01603
NC_000002.12:g.47402787C>T rs114222491 0.01530
NM_000251.3(MSH2):c.792+205C>T rs138284283 0.01355
NM_000251.3(MSH2):c.1077-259G>T rs2347793 0.01331
NM_000251.3(MSH2):c.2210+291C>G rs17224878 0.01068
NM_000251.3(MSH2):c.1387-307A>G rs55662637 0.00621
NM_000251.3(MSH2):c.646-161T>A rs17217800 0.00570
NM_000251.3(MSH2):c.*141T>G rs17225053 0.00526
NM_000251.3(MSH2):c.1077-225G>A rs192783837 0.00526
NM_000251.3(MSH2):c.984C>T (p.Ala328=) rs4987189 0.00495
NM_000251.3(MSH2):c.1077-229C>T rs148883469 0.00492
NM_000251.3(MSH2):c.1277-3155A>G rs149009810 0.00482
NM_000251.3(MSH2):c.1666T>C (p.Leu556=) rs61756466 0.00471
NM_000251.3(MSH2):c.1277-3256A>G rs143987692 0.00402
NM_000251.3(MSH2):c.1277-3380A>G rs114289535 0.00383
NM_000251.3(MSH2):c.1277-67A>G rs114494667 0.00325
NM_000251.3(MSH2):c.339G>A (p.Lys113=) rs35898375 0.00313
NM_000251.3(MSH2):c.1510+189C>G rs17218202 0.00287
NM_000251.2(MSH2):c.-185C>A rs188036046 0.00223
NM_000251.3(MSH2):c.*226A>G rs17225060 0.00201
NM_000251.3(MSH2):c.23C>T (p.Thr8Met) rs17217716 0.00184
NM_000251.1(MSH2):c.-179C>T rs17224094 0.00159
NM_000251.3(MSH2):c.1277-8T>C rs145400590 0.00159
NM_000251.3(MSH2):c.1387-8G>T rs187525243 0.00143
NM_000251.3(MSH2):c.1661+73A>G rs180805863 0.00142
NM_000251.3(MSH2):c.1737A>G (p.Lys579=) rs61756467 0.00138
NM_000251.3(MSH2):c.819A>G (p.Val273=) rs146577635 0.00101
NM_000251.3(MSH2):c.1759+57G>T rs17218363 0.00089
NM_000251.3(MSH2):c.55T>C (p.Phe19Leu) rs141711342 0.00063
NM_000251.3(MSH2):c.1563T>C (p.Tyr521=) rs63750330 0.00053
NM_000251.3(MSH2):c.815C>T (p.Ala272Val) rs34136999 0.00046
NM_000251.3(MSH2):c.1680T>C (p.Asn560=) rs200056411 0.00043
NM_000251.3(MSH2):c.1168C>T (p.Leu390Phe) rs17224367 0.00039
NM_000251.3(MSH2):c.1511-41G>C rs202215396 0.00038
NM_000251.3(MSH2):c.2154A>G (p.Gln718=) rs63750810 0.00033
NM_000251.3(MSH2):c.435T>G (p.Ile145Met) rs63750124 0.00031
NM_000251.3(MSH2):c.471C>A (p.Gly157=) rs61756463 0.00029
NM_000251.3(MSH2):c.1277-16T>C rs368653974 0.00024
NM_000251.3(MSH2):c.1787A>G (p.Asn596Ser) rs41295288 0.00022
NM_000251.3(MSH2):c.1255C>A (p.Gln419Lys) rs63750006 0.00019
NM_000251.3(MSH2):c.138C>G (p.His46Gln) rs33946261 0.00019
NM_000251.3(MSH2):c.1730T>C (p.Ile577Thr) rs63749910 0.00018
NM_000251.3(MSH2):c.1275A>G (p.Glu425=) rs63751650 0.00016
NM_000251.3(MSH2):c.2537A>G (p.Gln846Arg) rs140754514 0.00015
NM_000251.3(MSH2):c.1748A>G (p.Asn583Ser) rs201118107 0.00014
NM_000251.3(MSH2):c.-3G>C rs587779960 0.00013
NM_000251.3(MSH2):c.128A>G (p.Tyr43Cys) rs17217723 0.00011
NM_000251.3(MSH2):c.1461C>G (p.Asp487Glu) rs35107951 0.00011
NM_000251.3(MSH2):c.198C>T (p.Tyr66=) rs730881784 0.00011
NM_000251.3(MSH2):c.2203A>G (p.Ile735Val) rs2229061 0.00011
NM_000251.3(MSH2):c.2308A>G (p.Ile770Val) rs63750684 0.00011
NM_000251.3(MSH2):c.2785C>T (p.Arg929Ter) rs551060742 0.00011
NM_000251.3(MSH2):c.508C>G (p.Gln170Glu) rs63750843 0.00011
NM_000251.3(MSH2):c.1386+23T>G rs747646424 0.00010
NM_000251.3(MSH2):c.2210+7G>T rs374675118 0.00010
NM_000251.3(MSH2):c.114C>G (p.Asp38Glu) rs587779074 0.00009
NM_000251.3(MSH2):c.2367C>T (p.Ala789=) rs786202414 0.00009
NM_000251.3(MSH2):c.2802G>A (p.Thr934=) rs150259097 0.00009
NM_000251.3(MSH2):c.317G>A (p.Arg106Lys) rs41295286 0.00009
NM_000251.3(MSH2):c.1217G>A (p.Arg406Gln) rs146567853 0.00008
NM_000251.3(MSH2):c.1488A>G (p.Leu496=) rs267607960 0.00008
NM_000251.3(MSH2):c.1662-10C>T rs752606387 0.00008
NM_000251.3(MSH2):c.1690A>G (p.Thr564Ala) rs55778204 0.00008
NM_000251.3(MSH2):c.2500G>A (p.Ala834Thr) rs63750757 0.00008
NM_000251.3(MSH2):c.4G>A (p.Ala2Thr) rs63750466 0.00008
NM_000251.3(MSH2):c.820A>G (p.Ile274Val) rs371944271 0.00008
NM_000251.3(MSH2):c.913G>A (p.Ala305Thr) rs63751454 0.00008
NM_000251.3(MSH2):c.1045C>G (p.Pro349Ala) rs267607939 0.00007
NM_000251.3(MSH2):c.1560A>G (p.Gly520=) rs63750820 0.00007
NM_000251.3(MSH2):c.1638G>A (p.Lys546=) rs372350768 0.00007
NM_000251.3(MSH2):c.818T>C (p.Val273Ala) rs144288433 0.00007
NM_000251.3(MSH2):c.1077-7A>G rs370807334 0.00006
NM_000251.3(MSH2):c.2400A>G (p.Leu800=) rs201298777 0.00006
NM_000251.3(MSH2):c.382C>G (p.Leu128Val) rs145649774 0.00006
NM_000251.3(MSH2):c.499G>C (p.Asp167His) rs63750255 0.00006
NM_000251.3(MSH2):c.944G>T (p.Gly315Val) rs202026056 0.00006
NM_000251.3(MSH2):c.1842A>C (p.Gly614=) rs923770168 0.00005
NM_000251.3(MSH2):c.843A>T (p.Ser281=) rs150197753 0.00005
NC_000002.12:g.47402967G>C rs138068023 0.00004
NM_000251.2(MSH2):c.-102T>C rs17217709 0.00004
NM_000251.3(MSH2):c.*32G>C rs192502889 0.00004
NM_000251.3(MSH2):c.1830C>T (p.His610=) rs766326295 0.00004
NM_000251.3(MSH2):c.2211-6C>A rs267608003 0.00004
NM_000251.3(MSH2):c.2580G>A (p.Ser860=) rs752428475 0.00004
NM_000251.3(MSH2):c.287G>A (p.Arg96His) rs63750002 0.00004
NM_000251.3(MSH2):c.336C>A (p.Ser112=) rs34312619 0.00004
NM_000251.3(MSH2):c.1617T>C (p.Phe539=) rs730881759 0.00003
NM_000251.3(MSH2):c.1847C>G (p.Pro616Arg) rs587779965 0.00003
NM_000251.3(MSH2):c.1863A>T (p.Arg621=) rs786203119 0.00003
NM_000251.3(MSH2):c.1963G>A (p.Val655Ile) rs549467183 0.00003
NM_000251.3(MSH2):c.211+8C>T rs267607916 0.00003
NM_000251.3(MSH2):c.2528G>A (p.Cys843Tyr) rs747700106 0.00003
NM_000251.3(MSH2):c.835C>G (p.Leu279Val) rs375351205 0.00003
NM_000251.3(MSH2):c.1014A>C (p.Gly338=) rs774083607 0.00002
NM_000251.3(MSH2):c.1131A>G (p.Gln377=) rs181852377 0.00002
NM_000251.3(MSH2):c.1764T>C (p.Tyr588=) rs63750844 0.00002
NM_000251.3(MSH2):c.1854A>G (p.Pro618=) rs786203744 0.00002
NM_000251.3(MSH2):c.2006-36_2006-33dup rs587779126 0.00002
NM_000251.3(MSH2):c.2061C>G (p.Leu687=) rs63750032 0.00002
NM_000251.3(MSH2):c.304G>A (p.Val102Ile) rs193922373 0.00002
NM_000251.3(MSH2):c.438T>C (p.Gly146=) rs587779161 0.00002
NM_000251.3(MSH2):c.51C>A (p.Val17=) rs397515879 0.00002
NM_000251.3(MSH2):c.762T>C (p.Asn254=) rs587779180 0.00002
NM_000251.3(MSH2):c.105C>A (p.Arg35=) rs775554736 0.00001
NM_000251.3(MSH2):c.1077-15G>T rs753277524 0.00001
NM_000251.3(MSH2):c.1099G>A (p.Val367Ile) rs80285180 0.00001
NM_000251.3(MSH2):c.115C>A (p.Arg39=) rs786202334 0.00001
NM_000251.3(MSH2):c.1194A>G (p.Ala398=) rs1060504412 0.00001
NM_000251.3(MSH2):c.1254A>G (p.Ile418Met) rs751431238 0.00001
NM_000251.3(MSH2):c.1296G>A (p.Leu432=) rs141295984 0.00001
NM_000251.3(MSH2):c.132G>A (p.Thr44=) rs766856128 0.00001
NM_000251.3(MSH2):c.1344C>T (p.Ser448=) rs1010360604 0.00001
NM_000251.3(MSH2):c.1356A>G (p.Glu452=) rs63751212 0.00001
NM_000251.3(MSH2):c.1374A>G (p.Leu458=) rs767639853 0.00001
NM_000251.3(MSH2):c.1378A>G (p.Met460Val) rs575905950 0.00001
NM_000251.3(MSH2):c.1440A>G (p.Glu480=) rs138049198 0.00001
NM_000251.3(MSH2):c.159C>T (p.Ala53=) rs780178752 0.00001
NM_000251.3(MSH2):c.1760-10T>A rs767536391 0.00001
NM_000251.3(MSH2):c.1760-3C>T rs786202843 0.00001
NM_000251.3(MSH2):c.1866A>C (p.Pro622=) rs757766951 0.00001
NM_000251.3(MSH2):c.186G>A (p.Gly62=) rs750058876 0.00001
NM_000251.3(MSH2):c.1962C>T (p.Asp654=) rs751939698 0.00001
NM_000251.3(MSH2):c.2006-15T>C rs1057524452 0.00001
NM_000251.3(MSH2):c.2006-4G>A rs369853630 0.00001
NM_000251.3(MSH2):c.2006-9G>T rs985337130 0.00001
NM_000251.3(MSH2):c.2082T>C (p.Phe694=) rs748210094 0.00001
NM_000251.3(MSH2):c.2094G>A (p.Glu698=) rs773555449 0.00001
NM_000251.3(MSH2):c.2106G>A (p.Val702=) rs786201108 0.00001
NM_000251.3(MSH2):c.212-3A>T rs879255341 0.00001
NM_000251.3(MSH2):c.213A>G (p.Gly71=) rs878853808 0.00001
NM_000251.3(MSH2):c.2172G>A (p.Thr724=) rs370636719 0.00001
NM_000251.3(MSH2):c.2190G>A (p.Leu730=) rs864622370 0.00001
NM_000251.3(MSH2):c.2248T>C (p.Leu750=) rs527725593 0.00001
NM_000251.3(MSH2):c.2458+4T>C rs1038735071 0.00001
NM_000251.3(MSH2):c.2459-12A>C rs267608012 0.00001
NM_000251.3(MSH2):c.2579C>T (p.Ser860Leu) rs63750849 0.00001
NM_000251.3(MSH2):c.2595C>T (p.Ile865=) rs547695133 0.00001
NM_000251.3(MSH2):c.2640T>C (p.Gly880=) rs1368565489 0.00001
NM_000251.3(MSH2):c.2667C>G (p.Ser889=) rs561680100 0.00001
NM_000251.3(MSH2):c.274C>G (p.Leu92Val) rs587779154 0.00001
NM_000251.3(MSH2):c.2804G>A (p.Ter935=) rs876658335 0.00001
NM_000251.3(MSH2):c.285T>C (p.Val95=) rs1369335343 0.00001
NM_000251.3(MSH2):c.366+4A>C rs876659880 0.00001
NM_000251.3(MSH2):c.367-6A>G rs769501299 0.00001
NM_000251.3(MSH2):c.375T>G (p.Pro125=) rs1427268231 0.00001
NM_000251.3(MSH2):c.384C>A (p.Leu128=) rs766694099 0.00001
NM_000251.3(MSH2):c.459C>T (p.Ser153=) rs63751065 0.00001
NM_000251.3(MSH2):c.525G>A (p.Leu175=) rs771827041 0.00001
NM_000251.3(MSH2):c.613G>C (p.Glu205Gln) rs63749984 0.00001
NM_000251.3(MSH2):c.639G>A (p.Leu213=) rs751250018 0.00001
NM_000251.3(MSH2):c.63C>T (p.Arg21=) rs1060504419 0.00001
NM_000251.3(MSH2):c.645+3A>G rs587779168 0.00001
NM_000251.3(MSH2):c.646-3T>C rs267607930 0.00001
NM_000251.3(MSH2):c.669G>A (p.Leu223=) rs751195930 0.00001
NM_000251.3(MSH2):c.693C>T (p.Asp231=) rs541325199 0.00001
NM_000251.3(MSH2):c.714T>C (p.Tyr238=) rs369670665 0.00001
NM_000251.3(MSH2):c.726C>T (p.Asn242=) rs748427458 0.00001
NM_000251.3(MSH2):c.816G>A (p.Ala272=) rs368912987 0.00001
NM_000251.3(MSH2):c.942+5A>G rs769242733 0.00001
NM_000251.3(MSH2):c.972G>A (p.Gln324=) rs63750505 0.00001
NM_000251.3(MSH2):c.996G>A (p.Lys332=) rs863224343 0.00001
NM_000251.3(MSH2):c.*10_*12del rs764232113
NM_000251.3(MSH2):c.-8G>T rs1064795641
NM_000251.3(MSH2):c.1076+171del rs17217884
NM_000251.3(MSH2):c.108T>G (p.Leu36=) rs876659034
NM_000251.3(MSH2):c.1167A>G (p.Arg389=) rs2104439470
NM_000251.3(MSH2):c.1176G>A (p.Lys392=) rs1573484863
NM_000251.3(MSH2):c.1191A>G (p.Gln397=) rs768694189
NM_000251.3(MSH2):c.1239A>G (p.Gln413=)
NM_000251.3(MSH2):c.126C>T (p.Phe42=) rs730881766
NM_000251.3(MSH2):c.1276+132dup rs878894023
NM_000251.3(MSH2):c.1277-15A>T rs1553361106
NM_000251.3(MSH2):c.1277-3121_1277-3120insCA rs200224815
NM_000251.3(MSH2):c.1277-3127A>G
NM_000251.3(MSH2):c.1277-3128TA[6]
NM_000251.3(MSH2):c.1277-3257TA[3] rs374230278
NM_000251.3(MSH2):c.1277-3457T>C rs146685163
NM_000251.3(MSH2):c.1277-3505TG[7] rs533511906
NM_000251.3(MSH2):c.1277-7C>G rs375437307
NM_000251.3(MSH2):c.1341C>T (p.Phe447=) rs587781373
NM_000251.3(MSH2):c.135G>T (p.Ala45=) rs890172773
NM_000251.3(MSH2):c.1386+2694G>C
NM_000251.3(MSH2):c.1386+2715A>G
NM_000251.3(MSH2):c.1387-14_1387-11del rs370436680
NM_000251.3(MSH2):c.1389G>A (p.Val463=) rs1553365702
NM_000251.3(MSH2):c.1510+282C>T rs17218209
NM_000251.3(MSH2):c.1511-16C>T rs768540784
NM_000251.3(MSH2):c.1545C>T (p.Ser515=) rs1553366537
NM_000251.3(MSH2):c.15G>A (p.Pro5=) rs758054171
NM_000251.3(MSH2):c.1626A>G (p.Val542=) rs1553366635
NM_000251.3(MSH2):c.1632C>A (p.Ile544=) rs746286801
NM_000251.3(MSH2):c.1642G>T (p.Gly548Cys) rs63750538
NM_000251.3(MSH2):c.1656C>T (p.Thr552=) rs876660600
NM_000251.3(MSH2):c.1661+17T>G rs377461923
NM_000251.3(MSH2):c.1719C>G (p.Ala573=) rs1553367674
NM_000251.3(MSH2):c.1746C>T (p.Val582=) rs786201486
NM_000251.3(MSH2):c.1760-7del rs754968844
NM_000251.3(MSH2):c.1770A>G (p.Glu590=) rs760619442
NM_000251.3(MSH2):c.182A>C (p.Gln61Pro) rs587779113
NM_000251.3(MSH2):c.1869C>T (p.Ala623=) rs1553368623
NM_000251.3(MSH2):c.2043A>G (p.Gln681=) rs730881763
NM_000251.3(MSH2):c.2088A>G (p.Pro696=) rs878853807
NM_000251.3(MSH2):c.2166C>T (p.Val722=) rs1057520969
NM_000251.3(MSH2):c.2211-284del rs550967151
NM_000251.3(MSH2):c.2211-318del rs200377751
NM_000251.3(MSH2):c.2211-6C>T rs267608003
NM_000251.3(MSH2):c.2268C>G (p.Thr756=) rs1404389752
NM_000251.3(MSH2):c.2289A>G (p.Ala763=) rs1553369710
NM_000251.3(MSH2):c.2307C>T (p.Tyr769=) rs1573574086
NM_000251.3(MSH2):c.2398C>T (p.Leu800=) rs766586857
NM_000251.3(MSH2):c.2418C>T (p.Thr806=) rs876660451
NM_000251.3(MSH2):c.2458+8C>T rs189025757
NM_000251.3(MSH2):c.2459-277C>T rs139341221
NM_000251.3(MSH2):c.2580G>T (p.Ser860=) rs752428475
NM_000251.3(MSH2):c.2586A>C (p.Gly862=)
NM_000251.3(MSH2):c.2616G>A (p.Lys872=) rs1573579171
NM_000251.3(MSH2):c.2635-8T>A rs1573582329
NM_000251.3(MSH2):c.2700A>G (p.Ser900=) rs786202996
NM_000251.3(MSH2):c.2714C>G (p.Thr905Arg) rs267608022
NM_000251.3(MSH2):c.2714C>T (p.Thr905Ile) rs267608022
NM_000251.3(MSH2):c.273TCT[2] (p.Leu94del) rs267607919
NM_000251.3(MSH2):c.276T>G (p.Leu92=) rs1060504425
NM_000251.3(MSH2):c.2775A>G (p.Glu925=) rs1057521004
NM_000251.3(MSH2):c.2801C>T (p.Thr934Met) rs587779969
NM_000251.3(MSH2):c.366+88G>C
NM_000251.3(MSH2):c.403C>G (p.Leu135Val) rs193096019
NM_000251.3(MSH2):c.471C>T (p.Gly157=) rs61756463
NM_000251.3(MSH2):c.498G>C (p.Val166=)
NM_000251.3(MSH2):c.504C>T (p.Ser168=) rs1200735883
NM_000251.3(MSH2):c.507A>G (p.Ile169Met) rs748762580
NM_000251.3(MSH2):c.606C>G (p.Pro202=) rs63750600
NM_000251.3(MSH2):c.606C>T (p.Pro202=) rs63750600
NM_000251.3(MSH2):c.645+8A>T rs140217708
NM_000251.3(MSH2):c.67T>C (p.Phe23Leu) rs372619120
NM_000251.3(MSH2):c.6G>C (p.Ala2=) rs368270856
NM_000251.3(MSH2):c.6G>T (p.Ala2=) rs368270856
NM_000251.3(MSH2):c.849T>C (p.Asp283=) rs876659344
NM_000251.3(MSH2):c.939T>C (p.Phe313=) rs970103452
NM_000251.3(MSH2):c.942+17_942+29del rs11309117
NM_000251.3(MSH2):c.942+21_942+29del rs11309117
NM_000251.3(MSH2):c.942+25_942+29del rs11309117
NM_000251.3(MSH2):c.965G>T (p.Gly322Val) rs4987188
NM_000251.3(MSH2):c.978G>A (p.Leu326=) rs1060504418

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