ClinVar Miner

Variants in gene MSH3

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Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign not provided total
136 38 1069 320 18 1 1546

Condition and significance breakdown #

Total conditions: 7
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Condition pathogenic likely pathogenic uncertain significance likely benign benign not provided total
not provided 131 36 1043 291 14 0 1510
Hereditary cancer-predisposing syndrome 19 3 133 56 3 0 214
none provided 1 1 2 3 4 0 11
Familial adenomatous polyposis 4 5 1 3 0 0 0 9
not specified 0 0 2 1 0 0 3
Endometrial carcinoma 1 0 0 0 0 0 1
Endometrial carcinoma; Familial adenomatous polyposis 4 0 0 0 0 0 1 1

Submitter and significance breakdown #

Total submitters: 12
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Submitter pathogenic likely pathogenic uncertain significance likely benign benign not provided total
Invitae 131 35 1036 291 14 0 1507
Ambry Genetics 19 3 133 56 3 0 214
ARUP Laboratories, Molecular Genetics and Genomics,ARUP Laboratories 1 1 4 4 4 0 14
CeGaT Praxis fuer Humangenetik Tuebingen 0 1 4 1 0 0 6
Baylor Genetics 2 0 3 0 0 0 5
OMIM 4 0 0 0 0 0 4
Department of Pathology and Laboratory Medicine,Sinai Health System 0 0 3 0 0 0 3
Mendelics 0 1 0 0 0 0 1
Lineagen, Inc 0 0 1 0 0 0 1
Quest Diagnostics Nichols Institute San Juan Capistrano 0 0 1 0 0 0 1
GenomeConnect, ClinGen 0 0 0 0 0 1 1
Johns Hopkins Genomics, Johns Hopkins University 0 0 1 0 0 0 1

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