List of variants in gene MSH6 reported as likely benign for Carcinoma of colon

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 27

Download table as spreadsheet

HGVS	dbSNP	gnomAD frequency
NM_000179.3(MSH6):c.2272C>T (p.Leu758=)	rs56371757	0.01363
NM_000179.3(MSH6):c.2633T>C (p.Val878Ala)	rs2020912	0.00448
NM_000179.3(MSH6):c.431G>T (p.Ser144Ile)	rs3211299	0.00158
NM_000179.3(MSH6):c.3265T>C (p.Leu1089=)	rs34490141	0.00096
NM_000179.3(MSH6):c.1526T>C (p.Val509Ala)	rs63751005	0.00067
NM_000179.3(MSH6):c.663A>C (p.Glu221Asp)	rs41557217	0.00064
NM_000179.3(MSH6):c.1508C>G (p.Ser503Cys)	rs63750897	0.00059
NM_000179.3(MSH6):c.1932G>C (p.Arg644Ser)	rs34938432	0.00037
NM_000179.3(MSH6):c.2561A>T (p.Lys854Met)	rs34374438	0.00036
NM_000179.3(MSH6):c.4002-10T>A	rs545466048	0.00026
NM_000179.3(MSH6):c.2398G>C (p.Val800Leu)	rs61748083	0.00014
NM_000179.3(MSH6):c.102C>A (p.Ala34=)	rs201132087	0.00013
NM_000179.3(MSH6):c.124C>T (p.Pro42Ser)	rs34014629	0.00011
NM_000179.3(MSH6):c.926C>G (p.Ser309Cys)	rs544222338	0.00006
NM_000179.3(MSH6):c.2271C>T (p.Thr757=)	rs142172006	0.00004
NM_000179.3(MSH6):c.3557-3A>T	rs41295274	0.00004
NM_000179.3(MSH6):c.354A>G (p.Thr118=)	rs558590898	0.00002
NM_000179.3(MSH6):c.1133G>A (p.Arg378Lys)	rs587779205	0.00001
NM_000179.3(MSH6):c.2391C>T (p.Asp797=)	rs754870044	0.00001
NM_000179.3(MSH6):c.2526T>G (p.Ala842=)	rs772394197	0.00001
NM_000179.3(MSH6):c.3255C>G (p.Thr1085=)	rs371568610	0.00001
NM_000179.3(MSH6):c.4002-8A>C	rs778957100	0.00001
NM_000179.3(MSH6):c.668A>G (p.Asn223Ser)	rs587779316	0.00001
NM_000179.3(MSH6):c.1180T>G (p.Ser394Ala)	rs1553412587
NM_000179.3(MSH6):c.1890A>C (p.Ala630=)	rs1468271394
NM_000179.3(MSH6):c.3300G>C (p.Thr1100=)	rs540252208
NM_000179.3(MSH6):c.4001+11_4001+19del	rs2104569281

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.