ClinVar Miner

List of variants in gene MSH6 reported as likely pathogenic for Hereditary nonpolyposis colon cancer

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Total variants: 63
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HGVS dbSNP
NC_000002.12:g.(?_47803398)_(47803695_?)dup
NC_000002.12:g.(?_47805433)_(47806875_?)del
NC_000002.12:g.47799954_47804551del
NM_000179.2(MSH6):c.1109T>C (p.Leu370Ser) rs587779204
NM_000179.2(MSH6):c.1295T>C (p.Phe432Ser) rs750528093
NM_000179.2(MSH6):c.1304T>C (p.Leu435Pro) rs63751405
NM_000179.2(MSH6):c.1316A>G (p.Asp439Gly) rs786202363
NM_000179.2(MSH6):c.139_260+1878del
NM_000179.2(MSH6):c.1805C>A (p.Ser602Ter) rs730881816
NM_000179.2(MSH6):c.1912del (p.Glu639fs) rs1553413294
NM_000179.2(MSH6):c.2057G>A (p.Gly686Asp) rs587779227
NM_000179.2(MSH6):c.2080T>C (p.Cys694Arg) rs587779228
NM_000179.2(MSH6):c.2260dup (p.Thr754fs) rs1553413640
NM_000179.2(MSH6):c.2300C>T (p.Thr767Ile) rs587781462
NM_000179.2(MSH6):c.2314C>T (p.Arg772Trp) rs63750138
NM_000179.2(MSH6):c.260+2_260+3delinsAG rs1064794075
NM_000179.2(MSH6):c.2690dup (p.Asn897fs) rs1553414010
NM_000179.2(MSH6):c.2906A>G (p.Tyr969Cys) rs63749919
NM_000179.2(MSH6):c.3172+1G>T rs587779255
NM_000179.2(MSH6):c.3173-1_3173del rs587779256
NM_000179.2(MSH6):c.3173-2A>C rs1553331242
NM_000179.2(MSH6):c.3379_3438+5del rs1553331676
NM_000179.2(MSH6):c.3439-2A>T rs267608098
NM_000179.2(MSH6):c.3478G>T (p.Val1160Phe) rs376799914
NM_000179.2(MSH6):c.3528_3532del (p.Leu1177fs) rs863225408
NM_000179.2(MSH6):c.3556+1G>C rs1060502926
NM_000179.2(MSH6):c.3556+3_3556+13del rs587779269
NM_000179.2(MSH6):c.3557-1G>T rs1114167723
NM_000179.2(MSH6):c.3557-2A>T rs1558390582
NM_000179.2(MSH6):c.3632T>C (p.Leu1211Pro) rs864622041
NM_000179.2(MSH6):c.3646+1dup rs1553332768
NM_000179.2(MSH6):c.3646+2T>C rs1553332776
NM_000179.2(MSH6):c.3647delG rs1064795629
NM_000179.2(MSH6):c.3725G>A (p.Arg1242His) rs63750119
NM_000179.2(MSH6):c.3732_3735dup (p.Ser1246fs) rs1553333072
NM_000179.2(MSH6):c.3798_3801+9del rs1553333168
NM_000179.2(MSH6):c.3801+1G>T rs876660943
NM_000179.2(MSH6):c.3801+1_3801+5del rs1553333175
NM_000179.2(MSH6):c.3801+1del rs1553333185
NM_000179.2(MSH6):c.3802-7_3802-4del rs876661171
NM_000179.2(MSH6):c.3936_3951del (p.Ile1313fs) rs1553333635
NM_000179.2(MSH6):c.3996_3999dup (p.Arg1334fs) rs1553333753
NM_000179.2(MSH6):c.3G>T (p.Met1Ile) rs876660095
NM_000179.2(MSH6):c.4001+2T>C rs267608131
NM_000179.2(MSH6):c.4002-2A>G rs878853745
NM_000179.2(MSH6):c.458-1G>T rs267608035
NM_000179.2(MSH6):c.517_520del (p.Leu173fs) rs1553411419
NM_000179.2(MSH6):c.627+1G>A rs1572716545
NM_000179.2(MSH6):c.628-2A>G rs1114167725
NM_000179.3(MSH6):c.1357A>T (p.Lys453Ter)
NM_000179.3(MSH6):c.1836dup (p.Leu613fs)
NM_000179.3(MSH6):c.2419del (p.Glu807fs)
NM_000179.3(MSH6):c.3416dup rs587781544
NM_000179.3(MSH6):c.3556+2T>C
NM_000179.3(MSH6):c.3724C>A (p.Arg1242Ser) rs587779285
NM_000179.3(MSH6):c.3729_3731ATT[1] (p.Leu1244del) rs876658650
NM_000179.3(MSH6):c.3733_3739dup (p.Thr1247fs)
NM_000179.3(MSH6):c.628-2A>T
NM_001281492.1(MSH6):c.1225_1227CTT[1] (p.Leu410del) rs1064793600
NM_001281492.1(MSH6):c.1912_1914del (p.Pro638del) rs63750647
NM_001281492.1(MSH6):c.2647_2649AAG[1] (p.Lys884del) rs267608073
NM_001281492.1(MSH6):c.3149_3152CAGA[1] (p.Asp1051fs) rs1553332297
NM_001281492.1(MSH6):c.3606_3610dup (p.Arg1204fs) rs587779301

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