ClinVar Miner

List of variants in gene MSH6 reported as uncertain significance by Quest Diagnostics Nichols Institute San Juan Capistrano

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Total variants: 127
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HGVS dbSNP
NM_000179.2(MSH6):c.*1A>G rs587781604
NM_000179.2(MSH6):c.*24_*28delGTTGA rs587779200
NM_000179.2(MSH6):c.-2G>T rs374748889
NM_000179.2(MSH6):c.-8C>T rs565211544
NM_000179.2(MSH6):c.1037C>T (p.Ser346Phe) rs567785169
NM_000179.2(MSH6):c.1050C>T (p.Ala350=) rs730881802
NM_000179.2(MSH6):c.105C>T (p.Ala35=) rs998365223
NM_000179.2(MSH6):c.1061G>T (p.Gly354Val) rs730881788
NM_000179.2(MSH6):c.1078A>G (p.Ser360Gly) rs145994565
NM_000179.2(MSH6):c.107C>T (p.Ala36Val) rs61756469
NM_000179.2(MSH6):c.1081C>T (p.Arg361Cys) rs587782651
NM_000179.2(MSH6):c.1190A>G (p.Tyr397Cys) rs63750065
NM_000179.2(MSH6):c.1281C>T (p.Tyr427=) rs1553412720
NM_000179.2(MSH6):c.1292A>G (p.Lys431Arg) rs1558661244
NM_000179.2(MSH6):c.1406A>G (p.Tyr469Cys) rs748165218
NM_000179.2(MSH6):c.145G>T (p.Ala49Ser) rs745642001
NM_000179.2(MSH6):c.1498G>A (p.Ala500Thr) rs786204127
NM_000179.2(MSH6):c.1661G>A (p.Arg554His) rs730881791
NM_000179.2(MSH6):c.16A>C (p.Thr6Pro) rs200944853
NM_000179.2(MSH6):c.1729C>G (p.Arg577Gly) rs542838372
NM_000179.2(MSH6):c.1729C>T (p.Arg577Cys) rs542838372
NM_000179.2(MSH6):c.1793A>G (p.Lys598Arg) rs587779919
NM_000179.2(MSH6):c.1814C>G (p.Thr605Ser) rs587781616
NM_000179.2(MSH6):c.184C>T (p.Arg62Cys) rs876659508
NM_000179.2(MSH6):c.1867C>G (p.Pro623Ala) rs3136334
NM_000179.2(MSH6):c.1870G>A (p.Gly624Ser) rs868760377
NM_000179.2(MSH6):c.187T>C (p.Ser63Pro) rs763702846
NM_000179.2(MSH6):c.187T>G (p.Ser63Ala) rs763702846
NM_000179.2(MSH6):c.190G>C (p.Ala64Pro) rs587779921
NM_000179.2(MSH6):c.1915G>A (p.Glu639Lys) rs143517321
NM_000179.2(MSH6):c.1978A>C (p.Lys660Gln) rs1060502894
NM_000179.2(MSH6):c.2006T>C (p.Ile669Thr) rs555209664
NM_000179.2(MSH6):c.2203C>A (p.Leu735Ile) rs786204071
NM_000179.2(MSH6):c.2272C>G (p.Leu758Val) rs56371757
NM_000179.2(MSH6):c.2281A>G (p.Arg761Gly) rs199876321
NM_000179.2(MSH6):c.229C>T (p.Arg77Trp) rs745442468
NM_000179.2(MSH6):c.2300C>T (p.Thr767Ile) rs587781462
NM_000179.2(MSH6):c.2355T>A (p.His785Gln) rs1060502942
NM_000179.2(MSH6):c.2384T>C (p.Ile795Thr) rs202127474
NM_000179.2(MSH6):c.2408A>G (p.Asp803Gly) rs63751450
NM_000179.2(MSH6):c.2417C>G (p.Ser806Cys) rs372990379
NM_000179.2(MSH6):c.2419G>A (p.Glu807Lys) rs587779923
NM_000179.2(MSH6):c.2491C>G (p.Pro831Ala) rs267608053
NM_000179.2(MSH6):c.2555A>C (p.Lys852Thr) rs1114167796
NM_000179.2(MSH6):c.2555_2557AGA[2] (p.Lys854del) rs587782858
NM_000179.2(MSH6):c.256A>C (p.Thr86Pro) rs1553408451
NM_000179.2(MSH6):c.2597A>C (p.Lys866Thr) rs190075874
NM_000179.2(MSH6):c.2614A>G (p.Ile872Val) rs1060502939
NM_000179.2(MSH6):c.2641delinsAAAA (p.Gly881delinsLysSer) rs63751408
NM_000179.2(MSH6):c.2664G>C (p.Lys888Asn) rs730881798
NM_000179.2(MSH6):c.2667G>T (p.Gln889His) rs149945495
NM_000179.2(MSH6):c.2668G>T (p.Val890Phe) rs786202628
NM_000179.2(MSH6):c.2677C>G (p.Leu893Val) rs370754319
NM_000179.2(MSH6):c.2734T>C (p.Trp912Arg) rs1060502869
NM_000179.2(MSH6):c.2776C>T (p.Leu926Phe) rs587781318
NM_000179.2(MSH6):c.2780T>C (p.Ile927Thr) rs587779926
NM_000179.2(MSH6):c.2876G>A (p.Arg959His) rs757653982
NM_000179.2(MSH6):c.2899A>G (p.Ile967Val) rs876661067
NM_000179.2(MSH6):c.2927G>A (p.Arg976His) rs63751113
NM_000179.2(MSH6):c.2950A>C (p.Asn984His) rs146359682
NM_000179.2(MSH6):c.2959A>G (p.Thr987Ala) rs746631156
NM_000179.2(MSH6):c.2979A>T (p.Glu993Asp) rs370462886
NM_000179.2(MSH6):c.3037_3039AAG[1] (p.Lys1014del) rs267608073
NM_000179.2(MSH6):c.3047C>T (p.Ala1016Val) rs587779929
NM_000179.2(MSH6):c.3062C>G (p.Ala1021Gly) rs63750287
NM_000179.2(MSH6):c.3071G>A (p.Arg1024Gln) rs372705506
NM_000179.2(MSH6):c.3101G>C (p.Arg1034Pro) rs181727939
NM_000179.2(MSH6):c.3104G>A (p.Arg1035Gln) rs730881801
NM_000179.2(MSH6):c.3191C>T (p.Ala1064Val) rs369042519
NM_000179.2(MSH6):c.3203G>A (p.Arg1068Gln) rs398123230
NM_000179.2(MSH6):c.3226C>G (p.Arg1076Gly) rs63750617
NM_000179.2(MSH6):c.3232G>C (p.Val1078Leu) rs587779932
NM_000179.2(MSH6):c.3233T>C (p.Val1078Ala) rs376452612
NM_000179.2(MSH6):c.3242T>G (p.Leu1081Trp) rs1553331349
NM_000179.2(MSH6):c.3259C>T (p.Pro1087Ser) rs63750998
NM_000179.2(MSH6):c.3260C>A (p.Pro1087His) rs63750753
NM_000179.2(MSH6):c.3260C>G (p.Pro1087Arg) rs63750753
NM_000179.2(MSH6):c.3334G>A (p.Asp1112Asn) rs773955368
NM_000179.2(MSH6):c.3425C>T (p.Thr1142Met) rs267608089
NM_000179.2(MSH6):c.3478G>A (p.Val1160Ile) rs376799914
NM_000179.2(MSH6):c.3556+3G>A rs1057521667
NM_000179.2(MSH6):c.3557G>A (p.Gly1186Asp) rs587781690
NM_000179.2(MSH6):c.3600A>G (p.Ile1200Met) rs587781482
NM_000179.2(MSH6):c.3675G>A (p.Thr1225=) rs730881820
NM_000179.2(MSH6):c.3760G>C (p.Glu1254Gln) rs1558392392
NM_000179.2(MSH6):c.3772C>G (p.Gln1258Glu) rs63750554
NM_000179.2(MSH6):c.3788G>A (p.Arg1263His) rs147852216
NM_000179.2(MSH6):c.3800T>C (p.Met1267Thr) rs148445930
NM_000179.2(MSH6):c.3809T>C (p.Met1270Thr) rs777617756
NM_000179.2(MSH6):c.3824G>A (p.Cys1275Tyr) rs150990541
NM_000179.2(MSH6):c.3839A>C (p.Gln1280Pro) rs1210663110
NM_000179.2(MSH6):c.3845C>A (p.Thr1282Asn) rs876660361
NM_000179.2(MSH6):c.3851C>T (p.Thr1284Met) rs63750836
NM_000179.2(MSH6):c.3859T>C (p.Tyr1287His) rs1553333474
NM_000179.2(MSH6):c.3879T>C (p.Ala1293=) rs752369374
NM_000179.2(MSH6):c.3919A>T (p.Asn1307Tyr) rs730881808
NM_000179.2(MSH6):c.3968T>C (p.Phe1323Ser) rs1051564593
NM_000179.2(MSH6):c.3971_3973AGA[1] (p.Lys1325del) rs587779300
NM_000179.2(MSH6):c.3986C>T (p.Ser1329Leu) rs199594809
NM_000179.2(MSH6):c.3990A>G (p.Leu1330=) rs1558394684
NM_000179.2(MSH6):c.4000C>T (p.Arg1334Trp) rs773763465
NM_000179.2(MSH6):c.4002-10T>A rs545466048
NM_000179.2(MSH6):c.4039G>C (p.Ala1347Pro) rs730881809
NM_000179.2(MSH6):c.4061_*23dup (p.Leu1354_Ter1361=) rs760782238
NM_000179.2(MSH6):c.4077_4080dup (p.Ter1361IleextTer?) rs575068534
NM_000179.2(MSH6):c.448C>T (p.Pro150Ser) rs587782406
NM_000179.2(MSH6):c.455C>A (p.Thr152Lys) rs1553410385
NM_000179.2(MSH6):c.491A>C (p.His164Pro) rs146469162
NM_000179.2(MSH6):c.503C>G (p.Ala168Gly) rs774162322
NM_000179.2(MSH6):c.527T>C (p.Met176Thr) rs1553411432
NM_000179.2(MSH6):c.533G>A (p.Arg178His) rs786204186
NM_000179.2(MSH6):c.565_624del (p.Lys189_Met208del) rs1553411462
NM_000179.2(MSH6):c.628-7C>A rs373129248
NM_000179.2(MSH6):c.64A>G (p.Lys22Glu) rs1060502897
NM_000179.2(MSH6):c.713C>A (p.Ser238Tyr) rs587782510
NM_000179.2(MSH6):c.725G>C (p.Ser242Thr) rs1060502925
NM_000179.2(MSH6):c.733A>T (p.Ile245Leu) rs762168786
NM_000179.2(MSH6):c.753A>G (p.Ile251Met) rs587779321
NM_000179.2(MSH6):c.806C>G (p.Thr269Ser) rs587779322
NM_000179.2(MSH6):c.884A>G (p.Lys295Arg) rs267608051
NM_000179.2(MSH6):c.899G>A (p.Arg300Gln) rs55760494
NM_000179.2(MSH6):c.905G>C (p.Arg302Thr) rs587781510
NM_000179.2(MSH6):c.926C>G (p.Ser309Cys) rs544222338
NM_000179.2(MSH6):c.94G>T (p.Gly32Cys) rs776859837
NM_000179.2(MSH6):c.956C>T (p.Thr319Met) rs188252826
NM_000179.2(MSH6):c.980C>G (p.Thr327Ser) rs369568820
NM_000179.2(MSH6):c.998C>T (p.Thr333Ile) rs587781983

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