List of variants in gene combination MUTYH, TOE1 reported as uncertain significance for Hereditary cancer-predisposing syndrome

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Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 41

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HGVS	dbSNP	gnomAD frequency
NM_025077.4(TOE1):c.52+77G>A	rs3219466	0.02177
NM_001128425.2(MUTYH):c.17C>A (p.Ser6Tyr)	rs587782837	0.00002
NM_001128425.2(MUTYH):c.8C>G (p.Pro3Arg)	rs745424307	0.00001
NM_025077.4(TOE1):c.-37T>A	rs759654665	0.00001
NM_025077.4(TOE1):c.-38G>C	rs774530388	0.00001
NM_025077.4(TOE1):c.-39C>T	rs876658588	0.00001
NM_025077.4(TOE1):c.1A>G (p.Met1Val)	rs865954220	0.00001
NM_025077.4(TOE1):c.21T>C (p.Asp7=)	rs1216403097	0.00001
NM_025077.4(TOE1):c.5C>T (p.Ala2Val)	rs748689064	0.00001
NM_025077.4(TOE1):c.6C>T (p.Ala2=)	rs876659248	0.00001
NM_001128425.2(MUTYH):c.10C>G (p.Leu4Val)	rs587782404
NM_001128425.2(MUTYH):c.10C>T (p.Leu4Phe)	rs587782404
NM_001128425.2(MUTYH):c.13G>A (p.Val5Ile)	rs786201933
NM_001128425.2(MUTYH):c.13G>C (p.Val5Leu)	rs786201933
NM_001128425.2(MUTYH):c.13G>T (p.Val5Phe)	rs786201933
NM_001128425.2(MUTYH):c.17C>G (p.Ser6Cys)	rs587782837
NM_001128425.2(MUTYH):c.20G>T (p.Arg7Leu)	rs1114167687
NM_001128425.2(MUTYH):c.23T>C (p.Leu8Pro)
NM_001128425.2(MUTYH):c.23T>G (p.Leu8Arg)	rs1570591840
NM_001128425.2(MUTYH):c.28C>T (p.Arg10Cys)	rs1570591700
NM_001128425.2(MUTYH):c.29G>A (p.Arg10His)	rs755928199
NM_001128425.2(MUTYH):c.29G>C (p.Arg10Pro)	rs755928199
NM_001128425.2(MUTYH):c.31C>G (p.Leu11Val)	rs878854188
NM_001128425.2(MUTYH):c.32T>G (p.Leu11Arg)	rs752665489
NM_001128425.2(MUTYH):c.35G>C (p.Trp12Ser)	rs1064795596
NM_001128425.2(MUTYH):c.3G>A (p.Met1Ile)	rs757906591
NM_001128425.2(MUTYH):c.3G>C (p.Met1Ile)
NM_001128425.2(MUTYH):c.7C>G (p.Pro3Ala)	rs876659091
NM_001128425.2(MUTYH):c.8C>T (p.Pro3Leu)	rs745424307
NM_001128425.2(MUTYH):c.9_10delinsAA (p.Leu4Ile)	rs1064794772
NM_025077.4(TOE1):c.-38G>A	rs774530388
NM_025077.4(TOE1):c.-38dup	rs1557517901
NM_025077.4(TOE1):c.-40G>C	rs1553136962
NM_025077.4(TOE1):c.13A>G (p.Ser5Gly)	rs1646825989
NM_025077.4(TOE1):c.15T>A (p.Ser5Arg)	rs1057520831
NM_025077.4(TOE1):c.15T>G (p.Ser5Arg)	rs1057520831
NM_025077.4(TOE1):c.17A>G (p.Asp6Gly)	rs562733690
NM_025077.4(TOE1):c.2T>C (p.Met1Thr)	rs1646823787
NM_025077.4(TOE1):c.4G>C (p.Ala2Pro)	rs781609463
NM_025077.4(TOE1):c.5C>A (p.Ala2Asp)	rs748689064
NM_025077.4(TOE1):c.7G>A (p.Ala3Thr)

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