ClinVar Miner

List of variants in gene NOTCH3 reported as benign for not provided

Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:
Total variants: 192
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HGVS dbSNP gnomAD frequency
NM_000435.3(NOTCH3):c.5363-125C>T rs10415431 0.90728
NM_000435.3(NOTCH3):c.4563A>G (p.Pro1521=) rs1044006 0.90693
NM_000435.3(NOTCH3):c.5913+28T>G rs4809029 0.90682
NM_000435.3(NOTCH3):c.5362+3T>C rs1548555 0.90675
NM_000435.3(NOTCH3):c.5363-297G>A rs7250232 0.90672
NM_000435.3(NOTCH3):c.5362+122G>A rs1548554 0.90670
NM_000435.3(NOTCH3):c.5362+294_5362+295insC rs3214209 0.90661
NM_000435.3(NOTCH3):c.5816-8T>C rs4809030 0.90632
NM_000435.3(NOTCH3):c.5815+36G>A rs2074618 0.90515
NM_000435.3(NOTCH3):c.5815+124G>C rs2074617 0.90513
NM_000435.3(NOTCH3):c.5363-21G>A rs10416777 0.90510
NM_000435.3(NOTCH3):c.5363-17C>T rs2074619 0.90508
NM_000435.3(NOTCH3):c.5363-107G>A rs62113791 0.90499
NM_000435.3(NOTCH3):c.5363-104A>G rs45591935 0.90426
NM_000435.3(NOTCH3):c.5816-251A>G rs757474 0.90400
NM_000435.3(NOTCH3):c.4736+268T>G rs72992080 0.90027
NM_000435.3(NOTCH3):c.4736+284C>T rs113409991 0.89143
NM_000435.3(NOTCH3):c.1192+15A>G rs10423702 0.87325
NM_000435.3(NOTCH3):c.606A>G (p.Ala202=) rs1043994 0.87319
NM_000435.3(NOTCH3):c.5913+55A>G rs757472 0.86388
NM_000435.3(NOTCH3):c.1607-121T>C rs10408984 0.78272
NM_000435.3(NOTCH3):c.5199+132T>C rs7249115 0.78269
NM_000435.3(NOTCH3):c.2566+115G>A rs2074616 0.77830
NM_000435.3(NOTCH3):c.2742A>G (p.Pro914=) rs1043997 0.76937
NM_000435.3(NOTCH3):c.2792+21G>A rs11669982 0.76928
NM_000435.3(NOTCH3):c.6668C>T (p.Ala2223Val) rs1044009 0.69087
NM_000435.3(NOTCH3):c.1378+152A>G rs2238643 0.68687
NM_000435.3(NOTCH3):c.5815+172G>T rs2886698 0.68152
NM_000435.3(NOTCH3):c.3328-105C>T rs2074621 0.67138
NM_000435.3(NOTCH3):c.4892-22G>T rs2074620 0.59905
NM_000435.3(NOTCH3):c.2566+304C>T rs4809043 0.57936
NM_000435.3(NOTCH3):c.2792+116G>A rs11669950 0.57374
NM_000435.3(NOTCH3):c.3837+21T>A rs11670823 0.56639
NM_000435.3(NOTCH3):c.2538C>T (p.Cys846=) rs1043996 0.56438
NM_000435.3(NOTCH3):c.1951+113G>A rs7245563 0.28286
NM_000435.3(NOTCH3):c.303C>T (p.Thr101=) rs3815188 0.18114
NM_000435.3(NOTCH3):c.1952-227G>A rs10407433 0.17383
NM_000435.3(NOTCH3):c.5526T>C (p.Ala1842=) rs16980398 0.12317
NM_000435.3(NOTCH3):c.5362+168A>C rs10417352 0.12315
NM_000435.3(NOTCH3):c.3058G>C (p.Ala1020Pro) rs35769976 0.10508
NM_000435.3(NOTCH3):c.2995-60A>G rs57538005 0.09105
NM_000435.3(NOTCH3):c.3547G>A (p.Val1183Met) rs10408676 0.08167
NM_000435.3(NOTCH3):c.2566+95A>G rs8113116 0.08161
NC_000019.10:g.15201184T>G rs73926728 0.07960
NM_000435.3(NOTCH3):c.4891+23G>C rs56277836 0.07390
NM_000435.3(NOTCH3):c.197+215C>T rs73506364 0.07088
NM_000435.3(NOTCH3):c.5914-208C>T rs73504088 0.04118
NM_000435.3(NOTCH3):c.6438G>A (p.Ala2146=) rs1044008 0.03162
NM_000435.3(NOTCH3):c.6221C>T (p.Pro2074Leu) rs114447350 0.02709
NM_000435.3(NOTCH3):c.6753C>T (p.Ser2251=) rs61731975 0.02703
NM_000435.3(NOTCH3):c.1140T>C (p.Pro380=) rs61749020 0.02545
NC_000019.10:g.15201008G>T rs529259186 0.02197
NM_000435.3(NOTCH3):c.3399C>A (p.His1133Gln) rs112197217 0.01566
NM_000435.3(NOTCH3):c.1607-127T>C rs12980291 0.01561
NM_000435.3(NOTCH3):c.2039G>A (p.Arg680His) rs10406745 0.01547
NM_000435.3(NOTCH3):c.6102C>T (p.Pro2034=) rs114887570 0.01539
NM_000435.3(NOTCH3):c.6813T>C (p.Pro2271=) rs61731974 0.01445
NM_000435.3(NOTCH3):c.1487C>T (p.Pro496Leu) rs11670799 0.01273
NM_000435.3(NOTCH3):c.1782C>T (p.Gly594=) rs35793356 0.01231
NM_000435.3(NOTCH3):c.*23T>A rs73504084 0.00989
NM_000435.3(NOTCH3):c.5854G>A (p.Val1952Met) rs115582213 0.00841
NM_000435.3(NOTCH3):c.3143-29C>T rs137943075 0.00839
NM_000435.3(NOTCH3):c.2566+24G>T rs151276393 0.00824
NM_000435.3(NOTCH3):c.4044C>T (p.Gly1348=) rs78926093 0.00784
NM_000435.3(NOTCH3):c.197+24C>G rs188132716 0.00778
NM_000435.3(NOTCH3):c.1490C>T (p.Ser497Leu) rs114207045 0.00755
NM_000435.3(NOTCH3):c.1952-23G>A rs147014533 0.00747
NM_000435.3(NOTCH3):c.5400G>T (p.Gly1800=) rs34480308 0.00591
NM_000435.3(NOTCH3):c.3704A>T (p.His1235Leu) rs55882518 0.00433
NM_000435.3(NOTCH3):c.4679G>C (p.Arg1560Pro) rs78501403 0.00417
NM_000435.3(NOTCH3):c.3719-11C>T rs78907190 0.00367
NM_000435.3(NOTCH3):c.197+23C>A rs202151374 0.00365
NM_000435.3(NOTCH3):c.2202C>T (p.Ala734=) rs140040122 0.00306
NM_000435.3(NOTCH3):c.2411-4C>G rs190177286 0.00295
NM_000435.3(NOTCH3):c.5370C>T (p.Phe1790=) rs35887416 0.00287
NM_000435.3(NOTCH3):c.2507C>T (p.Thr836Ile) rs34338511 0.00222
NM_000435.3(NOTCH3):c.2724C>T (p.Phe908=) rs61731967 0.00222
NM_000435.3(NOTCH3):c.4552C>A (p.Leu1518Met) rs141320511 0.00217
NM_000435.3(NOTCH3):c.2175T>C (p.Ser725=) rs141993521 0.00214
NM_000435.3(NOTCH3):c.2300G>A (p.Arg767His) rs75291244 0.00213
NM_000435.3(NOTCH3):c.3718+13G>T rs201077354 0.00188
NM_000435.3(NOTCH3):c.509A>G (p.His170Arg) rs147373451 0.00184
NM_000435.3(NOTCH3):c.4374C>T (p.Cys1458=) rs150288106 0.00162
NM_000435.3(NOTCH3):c.3314G>C (p.Gly1105Ala) rs143764521 0.00158
NM_000435.3(NOTCH3):c.6237G>A (p.Gly2079=) rs376598183 0.00145
NM_000435.3(NOTCH3):c.2682C>T (p.Asn894=) rs138245070 0.00107
NM_000435.3(NOTCH3):c.4737-19C>T rs180755159 0.00105
NM_000435.3(NOTCH3):c.660C>T (p.Tyr220=) rs114457076 0.00091
NM_000435.3(NOTCH3):c.3691C>T (p.Arg1231Cys) rs201680145 0.00089
NM_000435.3(NOTCH3):c.1607-5C>A rs372869012 0.00081
NM_000435.3(NOTCH3):c.2835G>A (p.Ser945=) rs141346023 0.00081
NM_000435.3(NOTCH3):c.4025C>A (p.Ala1342Asp) rs888391580 0.00070
NM_000435.3(NOTCH3):c.5510G>A (p.Arg1837His) rs138265894 0.00066
NM_000435.3(NOTCH3):c.3327+24G>C rs202014036 0.00064
NM_000435.3(NOTCH3):c.338G>A (p.Arg113Gln) rs143385744 0.00064
NM_000435.3(NOTCH3):c.1931T>A (p.Val644Asp) rs148046938 0.00063
NM_000435.3(NOTCH3):c.1952-32T>G rs137877808 0.00051
NM_000435.3(NOTCH3):c.2411-11C>A rs201130717 0.00043
NM_000435.3(NOTCH3):c.4639C>G (p.Leu1547Val) rs150037063 0.00043
NM_000435.3(NOTCH3):c.3629G>A (p.Arg1210His) rs35031555 0.00041
NM_000435.3(NOTCH3):c.1194C>T (p.Gly398=) rs140368657 0.00036
NM_000435.3(NOTCH3):c.3658C>T (p.Arg1220Trp) rs115872852 0.00036
NM_000435.3(NOTCH3):c.2580C>T (p.Asn860=) rs201436750 0.00035
NM_000435.3(NOTCH3):c.5200-4C>A rs375036447 0.00035
NM_000435.3(NOTCH3):c.3523C>T (p.Arg1175Trp) rs200504060 0.00028
NM_000435.3(NOTCH3):c.3838-27C>T rs549483448 0.00027
NM_000435.3(NOTCH3):c.3170C>T (p.Ala1057Val) rs368146879 0.00026
NM_000435.3(NOTCH3):c.2183G>A (p.Arg728His) rs144935367 0.00024
NM_000435.3(NOTCH3):c.850G>A (p.Ala284Thr) rs149307620 0.00024
NM_000435.3(NOTCH3):c.340+14A>G rs202136001 0.00022
NM_000435.3(NOTCH3):c.2437G>A (p.Glu813Lys) rs375873637 0.00020
NM_000435.3(NOTCH3):c.3299G>A (p.Arg1100His) rs189545202 0.00016
NM_000435.3(NOTCH3):c.5460C>A (p.Ile1820=) rs114661066 0.00016
NM_000435.3(NOTCH3):c.996C>T (p.Arg332=) rs183500505 0.00016
NM_000435.3(NOTCH3):c.1760G>A (p.Arg587His) rs142787620 0.00014
NM_000435.3(NOTCH3):c.4455C>T (p.Asp1485=) rs552265898 0.00014
NM_000435.3(NOTCH3):c.499C>T (p.Pro167Ser) rs202157633 0.00014
NM_000435.3(NOTCH3):c.1677C>T (p.Cys559=) rs113216024 0.00013
NM_000435.3(NOTCH3):c.3569G>A (p.Arg1190His) rs372241697 0.00013
NM_000435.3(NOTCH3):c.135C>T (p.Asp45=) rs370177269 0.00012
NM_000435.3(NOTCH3):c.4348G>A (p.Ala1450Thr) rs201082692 0.00011
NM_000435.3(NOTCH3):c.5323G>A (p.Ala1775Thr) rs139983430 0.00009
NM_000435.3(NOTCH3):c.5376G>A (p.Pro1792=) rs374875084 0.00008
NM_000435.3(NOTCH3):c.1840+8C>T rs372100017 0.00006
NM_000435.3(NOTCH3):c.432C>T (p.Cys144=) rs748339634 0.00006
NM_000435.3(NOTCH3):c.5937C>T (p.Ala1979=) rs570392715 0.00006
NM_000435.3(NOTCH3):c.6666G>A (p.Pro2222=) rs769365145 0.00006
NM_000435.3(NOTCH3):c.6747C>T (p.Pro2249=) rs769454994 0.00006
NM_000435.3(NOTCH3):c.1567G>A (p.Val523Met) rs564452430 0.00005
NM_000435.3(NOTCH3):c.3327+10C>T rs747489033 0.00005
NM_000435.3(NOTCH3):c.591C>T (p.Pro197=) rs367943979 0.00005
NM_000435.3(NOTCH3):c.1036+10C>T rs776962888 0.00004
NM_000435.3(NOTCH3):c.1678G>A (p.Val560Met) rs200160665 0.00004
NM_000435.3(NOTCH3):c.223C>T (p.Arg75Trp) rs762164861 0.00004
NM_000435.3(NOTCH3):c.825G>A (p.Val275=) rs138837495 0.00004
NM_000435.3(NOTCH3):c.1692C>T (p.Ala564=) rs372158498 0.00003
NM_000435.3(NOTCH3):c.204G>A (p.Pro68=) rs772468516 0.00003
NM_000435.3(NOTCH3):c.5199+20C>T rs769829213 0.00002
NM_000435.3(NOTCH3):c.815C>T (p.Thr272Met) rs749561286 0.00002
NM_000435.3(NOTCH3):c.1059C>T (p.Asp353=) rs529200949 0.00001
NM_000435.3(NOTCH3):c.1752C>T (p.Asp584=) rs201207820 0.00001
NM_000435.3(NOTCH3):c.2053C>A (p.Pro685Thr) rs774900511 0.00001
NM_000435.3(NOTCH3):c.3327+11G>A rs777978969 0.00001
NM_000435.3(NOTCH3):c.4347C>T (p.Pro1449=) rs747087788 0.00001
NM_000435.3(NOTCH3):c.6654C>T (p.Gly2218=) rs528209250 0.00001
GRCh37/hg19 19p13.12(chr19:15270636-15325310)x3
GRCh37/hg19 19p13.12(chr19:15276755-15290236)x3
GRCh37/hg19 19p13.12(chr19:15278099-15290236)x3
NC_000019.10:g.15201219C>A rs11882186
NM_000435.3(NOTCH3):c.1036+15dup
NM_000435.3(NOTCH3):c.1037-19del rs751607564
NM_000435.3(NOTCH3):c.108G>A (p.Pro36=)
NM_000435.3(NOTCH3):c.1607-14T>C
NM_000435.3(NOTCH3):c.1620G>T (p.Thr540=) rs75617410
NM_000435.3(NOTCH3):c.1641C>T (p.Asp547=)
NM_000435.3(NOTCH3):c.1725G>A (p.Thr575=) rs79926127
NM_000435.3(NOTCH3):c.1919G>A (p.Arg640His)
NM_000435.3(NOTCH3):c.1951+38C>G rs78329155
NM_000435.3(NOTCH3):c.1951+38C>T rs78329155
NM_000435.3(NOTCH3):c.1952-11G>T
NM_000435.3(NOTCH3):c.197+243A>G rs10417567
NM_000435.3(NOTCH3):c.197+46C>G rs542120843
NM_000435.3(NOTCH3):c.2163G>A (p.Glu721=) rs375173938
NM_000435.3(NOTCH3):c.276C>T (p.Val92=)
NM_000435.3(NOTCH3):c.2792+108C>T rs79458848
NM_000435.3(NOTCH3):c.2793-115C>G rs7257550
NM_000435.3(NOTCH3):c.3901G>A (p.Gly1301Ser)
NM_000435.3(NOTCH3):c.4404-175_4404-172del rs71168591
NM_000435.3(NOTCH3):c.4404-176_4404-172del rs71168591
NM_000435.3(NOTCH3):c.4404-61A>G rs10422818
NM_000435.3(NOTCH3):c.4736+290C>T rs140109009
NM_000435.3(NOTCH3):c.4736+9dup rs369417981
NM_000435.3(NOTCH3):c.4899G>C (p.Pro1633=)
NM_000435.3(NOTCH3):c.5199+13dup
NM_000435.3(NOTCH3):c.5199+221C>T rs1859385
NM_000435.3(NOTCH3):c.5200-155_5200-152dup rs56343808
NM_000435.3(NOTCH3):c.5200-297C>A rs2074623
NM_000435.3(NOTCH3):c.5200-297C>T rs2074623
NM_000435.3(NOTCH3):c.5362+290T>G rs34740703
NM_000435.3(NOTCH3):c.5363-108T>C rs45504393
NM_000435.3(NOTCH3):c.5505T>C (p.Thr1835=)
NM_000435.3(NOTCH3):c.5668-11C>T rs199850662
NM_000435.3(NOTCH3):c.5816-211_5816-204del rs139966230
NM_000435.3(NOTCH3):c.5816-232_5816-223del rs1411423626
NM_000435.3(NOTCH3):c.5816-232_5816-229del rs55790175
NM_000435.3(NOTCH3):c.5913+229G>A rs757471
NM_000435.3(NOTCH3):c.5913+45T>C rs4809028
NM_000435.3(NOTCH3):c.5914-10G>C
NM_000435.3(NOTCH3):c.5914-269del rs71168583
NM_000435.3(NOTCH3):c.5914-287_5914-285dup rs71168583
NM_000435.3(NOTCH3):c.5914-287_5914-286dup rs71168583
NM_000435.3(NOTCH3):c.5943C>T (p.Arg1981=)

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