ClinVar Miner

Variants in gene OPRM1

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Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign drug response not provided total
0 0 2 2 3 453 1 458

Condition and significance breakdown #

Total conditions: 15
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Condition uncertain significance likely benign benign drug response not provided total
Tramadol response 0 0 0 453 0 453
not provided 1 2 1 0 0 4
not specified 0 0 2 0 0 2
Drugs used in opioid dependence response - Dosage, Efficacy, Metabolism/PK 0 0 0 1 0 1
Gestational diabetes mellitus uncontrolled 0 0 0 0 1 1
Opioid dependence 1 1 0 0 0 0 1
alfentanil response - Dosage, Efficacy, Metabolism/PK 0 0 0 1 0 1
buprenorphine response - Dosage, Efficacy, Metabolism/PK 0 0 0 1 0 1
ethanol response - Toxicity/ADR 0 0 0 1 0 1
fentanyl response - Dosage, Efficacy, Metabolism/PK 0 0 0 1 0 1
heroin response - Dosage, Efficacy, Metabolism/PK 0 0 0 1 0 1
morphine response - Dosage, Efficacy, Metabolism/PK 0 0 0 1 0 1
naloxone response - Efficacy 0 0 0 1 0 1
opioids response - Dosage, Efficacy, Metabolism/PK 0 0 0 1 0 1
tramadol response - Dosage, Efficacy, Metabolism/PK 0 0 0 1 0 1

Submitter and significance breakdown #

Total submitters: 8
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Submitter uncertain significance likely benign benign drug response not provided total
Bruce Budowle Laboratory,University of North Texas Health Science Center 0 0 0 453 0 453
Invitae 0 2 1 0 0 3
OMIM 1 0 0 0 0 1
Laboratory for Molecular Medicine,Partners HealthCare Personalized Medicine 0 0 1 0 0 1
Genomic Diagnostic Laboratory, Division of Genomic Diagnostics,Children's Hospital of Philadelphia 0 0 1 0 0 1
Lineagen, Inc 1 0 0 0 0 1
PharmGKB 0 0 0 1 0 1
Institute of Molecular and Cell Biology, University of Tartu 0 0 0 0 1 1

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