List of variants in gene POLA1 reported as benign by Labcorp Genetics (formerly Invitae), Labcorp

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 93

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HGVS	dbSNP	gnomAD frequency
NM_001330360.2(POLA1):c.3717C>A (p.Val1239=)	rs11573423	0.04855
NM_001330360.2(POLA1):c.1167C>T (p.Ile389=)	rs11573338	0.01962
NM_001330360.2(POLA1):c.1532-12A>G	rs41305181	0.01022
NM_001330360.2(POLA1):c.4356C>T (p.Tyr1452=)	rs11573531	0.00965
NM_001330360.2(POLA1):c.1200+13G>A	rs11573339	0.00717
NM_001330360.2(POLA1):c.1687-15C>T	rs11573348	0.00442
NM_001330360.2(POLA1):c.3622G>C (p.Asp1208His)	rs41548013	0.00404
NM_001330360.2(POLA1):c.2267A>G (p.Lys756Arg)	rs2230928	0.00390
NM_001330360.2(POLA1):c.557T>C (p.Ile186Thr)	rs61756399	0.00206
NM_001330360.2(POLA1):c.4185C>T (p.Tyr1395=)	rs61756363	0.00122
NM_001330360.2(POLA1):c.2236T>C (p.Tyr746His)	rs2230927	0.00115
NM_001330360.2(POLA1):c.3183C>T (p.Tyr1061=)	rs61751428	0.00059
NM_001330360.2(POLA1):c.3297-17T>G	rs192192226	0.00053
NM_001330360.2(POLA1):c.318A>G (p.Glu106=)	rs369570755	0.00034
NM_001330360.2(POLA1):c.3087C>T (p.Asn1029=)	rs143911626	0.00028
NM_001330360.2(POLA1):c.1021G>T (p.Ala341Ser)	rs143377461	0.00025
NM_001330360.2(POLA1):c.2471A>G (p.Asp824Gly)	rs139024287	0.00025
NM_001330360.2(POLA1):c.3857A>G (p.Lys1286Arg)	rs575609660	0.00019
NM_001330360.2(POLA1):c.4025G>A (p.Arg1342His)	rs147068943	0.00018
NM_001330360.2(POLA1):c.2348C>T (p.Ser783Phe)	rs367639262	0.00016
NM_001330360.2(POLA1):c.266-6C>T	rs752393487	0.00016
NM_001330360.2(POLA1):c.529C>T (p.Pro177Ser)	rs201649929	0.00012
NM_001330360.2(POLA1):c.3746C>T (p.Pro1249Leu)	rs140910158	0.00011
NM_001330360.2(POLA1):c.4261+5G>A	rs767946660	0.00011
NM_001330360.2(POLA1):c.707-19T>C	rs55652049	0.00011
NM_001330360.2(POLA1):c.3516C>G (p.Gly1172=)	rs200148911	0.00010
NM_001330360.2(POLA1):c.3901G>A (p.Val1301Ile)	rs56090108	0.00010
NM_001330360.2(POLA1):c.1834-9dup	rs746368334	0.00009
NM_001330360.2(POLA1):c.4221G>A (p.Ala1407=)	rs200725778	0.00007
NM_001330360.2(POLA1):c.820A>G (p.Met274Val)	rs182025721	0.00007
NM_001330360.2(POLA1):c.4351G>A (p.Gly1451Ser)	rs764912556	0.00006
NM_001330360.2(POLA1):c.3044A>G (p.Asn1015Ser)	rs772782830	0.00005
NM_001330360.2(POLA1):c.361G>A (p.Ala121Thr)	rs141903278	0.00005
NM_001330360.2(POLA1):c.1175C>T (p.Thr392Met)	rs944466441	0.00004
NM_001330360.2(POLA1):c.1217C>T (p.Thr406Met)	rs368074893	0.00004
NM_001330360.2(POLA1):c.3297-4G>A	rs778428449	0.00004
NM_001330360.2(POLA1):c.3472C>G (p.Leu1158Val)	rs200688540	0.00004
NM_001330360.2(POLA1):c.1168G>A (p.Glu390Lys)	rs766311613	0.00003
NM_001330360.2(POLA1):c.4079G>A (p.Arg1360His)	rs780353506	0.00003
NM_001330360.2(POLA1):c.520A>G (p.Thr174Ala)	rs779569608	0.00003
NM_001330360.2(POLA1):c.2347-3T>C	rs762022436	0.00002
NM_001330360.2(POLA1):c.2841+6T>C	rs766709057	0.00002
NM_001330360.2(POLA1):c.3721A>G (p.Ile1241Val)	rs762859477	0.00002
NM_001330360.2(POLA1):c.708C>T (p.Gly236=)	rs777745902	0.00002
NM_001330360.2(POLA1):c.1192C>T (p.Arg398Cys)
NM_001330360.2(POLA1):c.1200+7A>G
NM_001330360.2(POLA1):c.1480T>C (p.Leu494=)
NM_001330360.2(POLA1):c.1573A>G (p.Met525Val)
NM_001330360.2(POLA1):c.1577C>T (p.Ala526Val)
NM_001330360.2(POLA1):c.1633G>A (p.Val545Met)
NM_001330360.2(POLA1):c.1635G>A (p.Val545=)
NM_001330360.2(POLA1):c.1726T>C (p.Leu576=)
NM_001330360.2(POLA1):c.1771+16del	rs752493068
NM_001330360.2(POLA1):c.1771+16dup	rs752493068
NM_001330360.2(POLA1):c.1772-12dup	rs758157161
NM_001330360.2(POLA1):c.1812C>T (p.Phe604=)
NM_001330360.2(POLA1):c.1834-10del
NM_001330360.2(POLA1):c.1918A>G (p.Ile640Val)
NM_001330360.2(POLA1):c.1982A>G (p.Lys661Arg)
NM_001330360.2(POLA1):c.2083A>G (p.Met695Val)
NM_001330360.2(POLA1):c.218C>T (p.Ser73Leu)
NM_001330360.2(POLA1):c.2191A>G (p.Met731Val)
NM_001330360.2(POLA1):c.2409C>T (p.Tyr803=)
NM_001330360.2(POLA1):c.2510A>G (p.Lys837Arg)
NM_001330360.2(POLA1):c.2567-18G>A
NM_001330360.2(POLA1):c.2574T>C (p.Tyr858=)
NM_001330360.2(POLA1):c.2756G>T (p.Arg919Ile)
NM_001330360.2(POLA1):c.2874A>G (p.Thr958=)
NM_001330360.2(POLA1):c.3145G>A (p.Val1049Ile)
NM_001330360.2(POLA1):c.3296+8C>T
NM_001330360.2(POLA1):c.3297-16_3297-15insG
NM_001330360.2(POLA1):c.3364C>T (p.Leu1122=)
NM_001330360.2(POLA1):c.3429+14T>A
NM_001330360.2(POLA1):c.3430-16_3430-15del	rs781050525
NM_001330360.2(POLA1):c.3430-9C>G	rs548338291
NM_001330360.2(POLA1):c.3465A>G (p.Lys1155=)
NM_001330360.2(POLA1):c.3837C>T (p.Tyr1279=)
NM_001330360.2(POLA1):c.3916-14C>T
NM_001330360.2(POLA1):c.3957C>T (p.Ile1319=)
NM_001330360.2(POLA1):c.4048-10T>C
NM_001330360.2(POLA1):c.4086A>C (p.Arg1362=)
NM_001330360.2(POLA1):c.4180C>T (p.Leu1394=)
NM_001330360.2(POLA1):c.4205G>A (p.Arg1402Gln)
NM_001330360.2(POLA1):c.4262-16C>G	rs201894152
NM_001330360.2(POLA1):c.4360G>A (p.Glu1454Lys)
NM_001330360.2(POLA1):c.4384G>A (p.Ala1462Thr)
NM_001330360.2(POLA1):c.4395C>T (p.Ala1465=)	rs144848232
NM_001330360.2(POLA1):c.590C>T (p.Pro197Leu)
NM_001330360.2(POLA1):c.691C>T (p.Arg231Cys)
NM_001330360.2(POLA1):c.705T>C (p.Ala235=)
NM_001330360.2(POLA1):c.707-13A>G
NM_001330360.2(POLA1):c.897C>T (p.Thr299=)
NM_001330360.2(POLA1):c.909-13G>T

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