List of variants in gene POLE reported as likely benign by Mendelics

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 41

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HGVS	dbSNP	gnomAD frequency
NM_006231.4(POLE):c.776G>A (p.Arg259His)	rs61732929	0.00604
NM_006231.4(POLE):c.4259C>T (p.Ala1420Val)	rs41561818	0.00325
NM_006231.4(POLE):c.861T>A (p.Asp287Glu)	rs139075637	0.00122
NM_006231.4(POLE):c.4057A>G (p.Ser1353Gly)	rs141619382	0.00063
NM_006231.4(POLE):c.5659G>A (p.Val1887Met)	rs114119067	0.00047
NM_006231.4(POLE):c.2683G>A (p.Ala895Thr)	rs201115064	0.00024
NM_006231.4(POLE):c.561C>T (p.Tyr187=)	rs143938822	0.00021
NM_006231.4(POLE):c.1597G>A (p.Val533Met)	rs374140892	0.00018
NM_006231.4(POLE):c.6751T>C (p.Phe2251Leu)	rs373768478	0.00018
NM_006231.4(POLE):c.154C>T (p.Arg52Trp)	rs115452881	0.00016
NM_006231.4(POLE):c.6674G>A (p.Arg2225His)	rs538875477	0.00012
NM_006231.4(POLE):c.6531+6G>T	rs774747998	0.00010
NM_006231.4(POLE):c.6331-8C>T	rs769766403	0.00007
NM_006231.4(POLE):c.3054C>T (p.Tyr1018=)	rs201249963	0.00006
NM_006231.4(POLE):c.3939G>A (p.Thr1313=)	rs150282789	0.00004
NM_006231.4(POLE):c.4150-6C>T	rs756837862	0.00004
NM_006231.4(POLE):c.4307G>A (p.Arg1436Gln)	rs754518522	0.00004
NM_006231.4(POLE):c.1021-11C>T	rs781431436	0.00003
NM_006231.4(POLE):c.3090C>T (p.Phe1030=)	rs766306895	0.00003
NM_006231.4(POLE):c.3228C>T (p.Cys1076=)	rs767929667	0.00003
NM_006231.4(POLE):c.3276-30C>T	rs773248517	0.00001
NM_006231.4(POLE):c.4427T>G (p.Phe1476Cys)	rs985504177	0.00001
NM_006231.4(POLE):c.5678+3G>A	rs1060500826	0.00001
NM_006231.4(POLE):c.5866G>A (p.Glu1956Lys)	rs749992643	0.00001
NM_006231.4(POLE):c.5900C>T (p.Ala1967Val)	rs201273415	0.00001
NM_006231.4(POLE):c.6540G>A (p.Ala2180=)	rs746976542	0.00001
NM_006231.4(POLE):c.6775C>T (p.Arg2259Trp)	rs866548835	0.00001
NM_006231.4(POLE):c.1520T>C (p.Val507Ala)	rs904849438
NM_006231.4(POLE):c.2090C>G (p.Pro697Arg)	rs36120395
NM_006231.4(POLE):c.2340G>C (p.Ser780=)	rs5744822
NM_006231.4(POLE):c.2811C>T (p.Tyr937=)	rs1593777350
NM_006231.4(POLE):c.2865-17_2865-14dup	rs369732588
NM_006231.4(POLE):c.2865-3C>T	rs1203095918
NM_006231.4(POLE):c.2865-3_2865del	rs1593776411
NM_006231.4(POLE):c.3275+38_3275+88del	rs1565955594
NM_006231.4(POLE):c.3582+34G>A	rs753702996
NM_006231.4(POLE):c.4645C>G (p.Pro1549Ala)	rs147500308
NM_006231.4(POLE):c.5679-3C>T	rs1555221512
NM_006231.4(POLE):c.6137-50C>T	rs779908266
NM_006231.4(POLE):c.6334C>T (p.Leu2112=)	rs373443211
NM_006231.4(POLE):c.6765C>T (p.Ile2255=)	rs376336585

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