List of variants in gene POLR3A reported as uncertain significance by GeneDx

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 28

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HGVS	dbSNP	gnomAD frequency
NM_007055.4(POLR3A):c.4057A>G (p.Met1353Val)	rs147168447	0.00051
NM_007055.4(POLR3A):c.1910-13A>G	rs375882550	0.00041
NM_007055.4(POLR3A):c.3698G>A (p.Arg1233Gln)	rs769323808	0.00008
NM_007055.4(POLR3A):c.2006G>A (p.Arg669Gln)	rs770551721	0.00006
NM_007055.4(POLR3A):c.3388G>A (p.Val1130Ile)	rs199581222	0.00006
NM_007055.4(POLR3A):c.1901A>G (p.Asn634Ser)	rs376651203	0.00003
NM_007055.4(POLR3A):c.1802T>A (p.Phe601Tyr)	rs1278152116	0.00002
NM_007055.4(POLR3A):c.1847A>C (p.Asn616Thr)	rs779523101	0.00002
NM_007055.4(POLR3A):c.1029A>T (p.Gln343His)	rs774558569	0.00001
NM_007055.4(POLR3A):c.1390C>T (p.Arg464Trp)	rs771732436	0.00001
NM_007055.4(POLR3A):c.1572+5G>A	rs1440024141	0.00001
NM_007055.4(POLR3A):c.1682G>A (p.Arg561Gln)	rs753456807	0.00001
NM_007055.4(POLR3A):c.1787C>T (p.Thr596Met)	rs756953635	0.00001
NM_007055.4(POLR3A):c.2434G>A (p.Gly812Ser)	rs372788440	0.00001
NM_007055.4(POLR3A):c.2542T>C (p.Phe848Leu)	rs1211210077	0.00001
NM_007055.4(POLR3A):c.2672G>A (p.Arg891Gln)	rs1192248453	0.00001
NM_007055.4(POLR3A):c.1360C>T (p.Leu454Phe)
NM_007055.4(POLR3A):c.1771-5C>G	rs199733994
NM_007055.4(POLR3A):c.1771-7C>A	rs201314157
NM_007055.4(POLR3A):c.2300G>T (p.Cys767Phe)	rs1847364681
NM_007055.4(POLR3A):c.2470C>T (p.His824Tyr)	rs1365082077
NM_007055.4(POLR3A):c.2618G>A (p.Arg873Gln)	rs2131937171
NM_007055.4(POLR3A):c.3014G>T (p.Arg1005Leu)	rs200118797
NM_007055.4(POLR3A):c.3100G>T (p.Gly1034Cys)	rs1221825194
NM_007055.4(POLR3A):c.3562G>A (p.Val1188Met)	rs140432781
NM_007055.4(POLR3A):c.3593A>G (p.Lys1198Arg)	rs1589303073
NM_007055.4(POLR3A):c.3864G>A (p.Met1288Ile)	rs1847140610
NM_007055.4(POLR3A):c.51C>G (p.His17Gln)	rs2131962032

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