ClinVar Miner

List of variants in gene PTPN11 reported as likely benign by GeneDx

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Gene type:
ClinVar version:
Total variants: 57
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HGVS dbSNP gnomAD frequency
NM_002834.5(PTPN11):c.*32+267C>T rs76662479 0.02729
NM_002834.5(PTPN11):c.854-223C>T rs73209632 0.02415
NM_002834.5(PTPN11):c.643-340T>C rs11066313 0.02313
NM_002834.5(PTPN11):c.1599+229G>A rs7974468 0.00904
NM_002834.5(PTPN11):c.525+78A>G rs114073655 0.00844
NM_002834.5(PTPN11):c.1379+308C>T rs116680276 0.00399
NM_002834.5(PTPN11):c.642+41T>G rs375023869 0.00043
NM_002834.5(PTPN11):c.1447+28C>T rs370390890 0.00015
NM_002834.5(PTPN11):c.1224+15G>A rs373271861 0.00011
NM_002834.5(PTPN11):c.137+49A>T rs761259292 0.00010
NM_002834.5(PTPN11):c.1449T>G (p.Gly483=) rs143238917 0.00009
NM_002834.5(PTPN11):c.1362G>A (p.Pro454=) rs771967829 0.00008
NM_002834.5(PTPN11):c.1740T>C (p.Tyr580=) rs139188627 0.00008
NM_002834.5(PTPN11):c.1678C>T (p.Leu560Phe) rs397516797 0.00007
NM_002834.5(PTPN11):c.132C>T (p.Ser44=) rs397507502 0.00006
NM_002834.5(PTPN11):c.1682C>T (p.Pro561Leu) rs141140214 0.00006
NM_002834.5(PTPN11):c.392A>G (p.Lys131Arg) rs397516805 0.00006
NM_002834.5(PTPN11):c.426C>T (p.Ser142=) rs199498784 0.00006
NM_002834.5(PTPN11):c.616T>C (p.Leu206=) rs78376169 0.00006
NM_002834.5(PTPN11):c.853+17C>T rs746692191 0.00006
NM_002834.5(PTPN11):c.1143C>T (p.Gly381=) rs781677115 0.00004
NM_002834.5(PTPN11):c.1278C>T (p.His426=) rs886038519 0.00004
NM_002834.5(PTPN11):c.854-19T>G rs751780145 0.00004
NM_002834.5(PTPN11):c.138-4T>G rs959868124 0.00003
NM_002834.5(PTPN11):c.540C>T (p.Asp180=) rs753269427 0.00003
NM_002834.5(PTPN11):c.137+42A>G rs537273886 0.00002
NM_002834.5(PTPN11):c.1649C>T (p.Ala550Val) rs767712281 0.00002
NM_002834.5(PTPN11):c.1011G>A (p.Thr337=) rs371951288 0.00001
NM_002834.5(PTPN11):c.1023T>C (p.Phe341=) rs762516252 0.00001
NM_002834.5(PTPN11):c.1047C>T (p.Asn349=) rs1222504763 0.00001
NM_002834.5(PTPN11):c.1048T>G (p.Ser350Ala) rs146571700 0.00001
NM_002834.5(PTPN11):c.1173C>T (p.Ser391=) rs770730416 0.00001
NM_002834.5(PTPN11):c.1467C>T (p.Asp489=) rs539373294 0.00001
NM_002834.5(PTPN11):c.324C>A (p.Thr108=) rs1352499844 0.00001
NM_002834.5(PTPN11):c.537C>T (p.Tyr179=) rs141015445 0.00001
NM_002834.5(PTPN11):c.66A>G (p.Thr22=) rs397516808 0.00001
NM_002834.5(PTPN11):c.*33-144del rs1191524369
NM_002834.5(PTPN11):c.*33-145_*33-144dup rs1191524369
NM_002834.5(PTPN11):c.*33-17_*33-13del rs730880991
NM_002834.5(PTPN11):c.*41_*46del rs886048967
NM_002834.5(PTPN11):c.*6C>T rs2135930915
NM_002834.5(PTPN11):c.-13G>A rs760374212
NM_002834.5(PTPN11):c.114T>G (p.Pro38=) rs758209360
NM_002834.5(PTPN11):c.1281C>T (p.Gly427=) rs753173299
NM_002834.5(PTPN11):c.138-216del rs369558589
NM_002834.5(PTPN11):c.1448-8C>T rs1555270633
NM_002834.5(PTPN11):c.1599+4C>A rs142606486
NM_002834.5(PTPN11):c.1653C>T (p.Asp551=) rs2135928776
NM_002834.5(PTPN11):c.333-262dup rs200651902
NM_002834.5(PTPN11):c.333-4T>C rs1555267812
NM_002834.5(PTPN11):c.372A>G (p.Lys124=) rs1035774225
NM_002834.5(PTPN11):c.525+275del rs376601242
NM_002834.5(PTPN11):c.525+275dup rs376601242
NM_002834.5(PTPN11):c.526-11T>C rs1555267925
NM_002834.5(PTPN11):c.526-33_526-31del rs142777663
NM_002834.5(PTPN11):c.642+158_642+159dup rs753974743
NM_002834.5(PTPN11):c.643-62dup rs140552217

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