ClinVar Miner

Variants in gene combination RAD51D, RAD51L3-RFFL

See also:
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign risk factor total
50 49 376 264 21 2 679

Condition and significance breakdown #

Total conditions: 9
Download table as spreadsheet
Condition pathogenic likely pathogenic uncertain significance likely benign benign risk factor total
Hereditary cancer-predisposing syndrome 35 21 257 180 10 0 484
Breast-ovarian cancer, familial 4 33 27 197 104 12 2 354
not provided 13 11 94 11 7 0 133
not specified 0 0 29 96 18 0 130
Hereditary breast and ovarian cancer syndrome 4 3 34 1 0 0 42
Breast and Ovarian Cancer Susceptibility 0 0 15 14 0 0 29
Ovarian Neoplasms 2 2 0 0 0 0 4
Inborn genetic diseases 0 0 1 0 0 0 1
Lynch syndrome I 0 1 0 0 0 0 1

Submitter and significance breakdown #

Total submitters: 23
Download table as spreadsheet
Submitter pathogenic likely pathogenic uncertain significance likely benign benign risk factor total
Invitae 32 15 190 82 9 0 328
Ambry Genetics 28 17 187 84 4 0 320
Color 16 7 143 133 10 0 309
GeneDx 13 11 74 88 15 0 201
Counsyl 6 13 22 27 4 0 72
Integrated Genetics/Laboratory Corporation of America 3 1 36 6 4 0 50
Mendelics 3 2 34 1 0 0 40
Quest Diagnostics Nichols Institute San Juan Capistrano 3 0 20 11 5 0 37
Illumina Clinical Services Laboratory,Illumina 0 0 15 14 0 0 29
PreventionGenetics 1 0 7 5 6 0 19
GeneKor MSA 0 0 13 0 0 0 13
EGL Genetic Diagnostics,Eurofins Clinical Diagnostics 1 0 6 3 2 0 12
Fulgent Genetics 2 1 6 0 0 0 9
True Health Diagnostics 0 0 1 6 1 0 8
ARUP Laboratories, Molecular Genetics and Genomics,ARUP Laboratories 0 0 1 0 3 0 4
German Consortium for Hereditary Breast and Ovarian Cancer Center Cologne,University Hospital Cologne 2 2 0 0 0 0 4
OMIM 0 0 0 0 0 2 2
University of Washington Department of Laboratory Medicine,University of Washington 0 0 1 1 0 0 2
Genetic Services Laboratory, University of Chicago 0 0 0 1 0 0 1
Division of Genomic Diagnostics,The Children's Hospital of Philadelphia 0 0 1 0 0 0 1
Institute for Biomarker Research,Medical Diagnostic Laboratories, L.L.C. 0 0 1 0 0 0 1
CeGaT Praxis fuer Humangenetik Tuebingen 0 0 1 0 0 0 1
Clinical Cancer Genetics and Family Consultants,Athens Medical Center 0 1 0 0 0 0 1

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.