ClinVar Miner

List of variants in gene SIRT1 reported as uncertain significance

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Gene type:
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Total variants: 70
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HGVS dbSNP gnomAD frequency
NM_012238.5(SIRT1):c.1071A>T (p.Gln357His) rs116374368 0.00017
NM_012238.5(SIRT1):c.535A>G (p.Arg179Gly) rs200805107 0.00013
NM_012238.5(SIRT1):c.2099A>G (p.Asn700Ser) rs116459300 0.00012
NM_012238.5(SIRT1):c.1617T>G (p.Ser539Arg) rs192990424 0.00007
NM_012238.5(SIRT1):c.1907G>A (p.Arg636Gln) rs771135356 0.00007
NM_012238.5(SIRT1):c.446G>A (p.Gly149Asp) rs978488168 0.00006
NM_012238.5(SIRT1):c.578T>C (p.Met193Thr) rs200994303 0.00004
NM_012238.5(SIRT1):c.1274C>G (p.Ala425Gly) rs201635394 0.00003
NM_012238.5(SIRT1):c.1906C>T (p.Arg636Trp) rs201647881 0.00003
NM_012238.5(SIRT1):c.1993G>A (p.Val665Ile) rs201730062 0.00003
NM_012238.5(SIRT1):c.896T>C (p.Ile299Thr) rs199983221 0.00003
NM_012238.5(SIRT1):c.2109A>C (p.Glu703Asp) rs201327262 0.00002
NM_012238.5(SIRT1):c.1061C>T (p.Ala354Val) rs141528984 0.00001
NM_012238.5(SIRT1):c.1289A>G (p.Lys430Arg) rs772640272 0.00001
NM_012238.5(SIRT1):c.1417C>T (p.His473Tyr) rs751498023 0.00001
NM_012238.5(SIRT1):c.1510C>A (p.Pro504Thr) rs116499760 0.00001
NM_012238.5(SIRT1):c.1969G>A (p.Val657Ile) rs199502996 0.00001
NM_012238.5(SIRT1):c.2066T>G (p.Met689Arg) rs750707792 0.00001
NM_012238.5(SIRT1):c.2098A>C (p.Asn700His) rs747251569 0.00001
NM_012238.5(SIRT1):c.2132G>C (p.Arg711Thr) rs774376548 0.00001
NM_012238.5(SIRT1):c.2169T>A (p.Asp723Glu) rs775109357 0.00001
NM_012238.5(SIRT1):c.353A>G (p.Asp118Gly) rs1842453200 0.00001
NM_012238.5(SIRT1):c.392A>G (p.Glu131Gly) rs1406007212 0.00001
NM_012238.5(SIRT1):c.475T>C (p.Ser159Pro) rs200660028 0.00001
NM_012238.5(SIRT1):c.557C>G (p.Thr186Ser) rs201841214 0.00001
NM_012238.5(SIRT1):c.580A>G (p.Ile194Val) rs1292146988 0.00001
NM_012238.5(SIRT1):c.631C>A (p.Pro211Thr) rs201007799 0.00001
NM_012238.5(SIRT1):c.841G>A (p.Ala281Thr) rs1842572334 0.00001
NM_012238.5(SIRT1):c.998C>T (p.Ser333Leu) rs200610338 0.00001
NC_000010.10:g.(?_69644213)_(69651332_?)dup
NM_012238.5(SIRT1):c.1078A>G (p.Ile360Val)
NM_012238.5(SIRT1):c.1122dup (p.Lys375Ter) rs2492951288
NM_012238.5(SIRT1):c.1125A>C (p.Lys375Asn) rs2492951297
NM_012238.5(SIRT1):c.1151G>A (p.Arg384Gln)
NM_012238.5(SIRT1):c.1195C>T (p.Pro399Ser) rs1047393773
NM_012238.5(SIRT1):c.1231A>G (p.Ile411Val) rs149206117
NM_012238.5(SIRT1):c.1246G>C (p.Glu416Gln)
NM_012238.5(SIRT1):c.1255C>A (p.Pro419Thr) rs775426483
NM_012238.5(SIRT1):c.1325C>G (p.Ser442Cys)
NM_012238.5(SIRT1):c.1497A>C (p.Lys499Asn) rs1173354902
NM_012238.5(SIRT1):c.1565C>T (p.Ala522Val)
NM_012238.5(SIRT1):c.1605AGA[1] (p.Glu536del) rs2492964168
NM_012238.5(SIRT1):c.1655T>C (p.Ile552Thr)
NM_012238.5(SIRT1):c.1760A>T (p.Asn587Ile) rs2492964799
NM_012238.5(SIRT1):c.1783A>G (p.Met595Val)
NM_012238.5(SIRT1):c.1810G>A (p.Gly604Ser)
NM_012238.5(SIRT1):c.1900A>G (p.Ser634Gly) rs2492965440
NM_012238.5(SIRT1):c.1936C>A (p.Pro646Thr)
NM_012238.5(SIRT1):c.1958A>G (p.His653Arg)
NM_012238.5(SIRT1):c.1994T>A (p.Val665Asp)
NM_012238.5(SIRT1):c.2030G>A (p.Ser677Asn)
NM_012238.5(SIRT1):c.2063C>A (p.Pro688His) rs765609303
NM_012238.5(SIRT1):c.2065A>G (p.Met689Val)
NM_012238.5(SIRT1):c.2066T>A (p.Met689Lys) rs750707792
NM_012238.5(SIRT1):c.2158G>A (p.Asp720Asn) rs2492974840
NM_012238.5(SIRT1):c.2183A>C (p.Asn728Thr) rs761406151
NM_012238.5(SIRT1):c.2206G>A (p.Glu736Lys) rs1564896279
NM_012238.5(SIRT1):c.2235_2238del (p.Lys746fs) rs1432077432
NM_012238.5(SIRT1):c.320T>C (p.Leu107Pro) rs587776957
NM_012238.5(SIRT1):c.372CGA[2] (p.Asp126_Asp127del) rs751108703
NM_012238.5(SIRT1):c.372CGA[5] (p.Asp127dup) rs751108703
NM_012238.5(SIRT1):c.403GCG[4] (p.Ala139del) rs36062014
NM_012238.5(SIRT1):c.403GCG[6] (p.Ala139dup) rs36062014
NM_012238.5(SIRT1):c.436C>G (p.Leu146Val) rs1842500910
NM_012238.5(SIRT1):c.438_440del (p.Leu147del) rs753268782
NM_012238.5(SIRT1):c.492GGA[1] (p.Glu165del) rs1166803467
NM_012238.5(SIRT1):c.689A>T (p.Glu230Val) rs2492897027
NM_012238.5(SIRT1):c.735T>A (p.Asp245Glu) rs201479376
NM_012238.5(SIRT1):c.829G>A (p.Asp277Asn)
NM_012238.5(SIRT1):c.913G>C (p.Asp305His)

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