List of variants in gene SOS1 reported as pathogenic by Invitae

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 32

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HGVS	dbSNP	gnomAD frequency
NM_005633.4(SOS1):c.1132A>G (p.Thr378Ala)	rs397517146
NM_005633.4(SOS1):c.1294T>A (p.Trp432Arg)
NM_005633.4(SOS1):c.1294T>C (p.Trp432Arg)	rs267607080
NM_005633.4(SOS1):c.1297G>A (p.Glu433Lys)	rs397517147
NM_005633.4(SOS1):c.1300G>A (p.Gly434Arg)	rs397517148
NM_005633.4(SOS1):c.1300G>C (p.Gly434Arg)	rs397517148
NM_005633.4(SOS1):c.1310T>C (p.Ile437Thr)	rs397517150
NM_005633.4(SOS1):c.1322G>A (p.Cys441Tyr)	rs727504295
NM_005633.4(SOS1):c.1394A>G (p.Asp465Gly)
NM_005633.4(SOS1):c.1642A>C (p.Ser548Arg)	rs397517149
NM_005633.4(SOS1):c.1644T>A (p.Ser548Arg)	rs730881045
NM_005633.4(SOS1):c.1649T>C (p.Leu550Pro)	rs397517153
NM_005633.4(SOS1):c.1654A>G (p.Arg552Gly)	rs137852814
NM_005633.4(SOS1):c.1655G>A (p.Arg552Lys)	rs397517154
NM_005633.4(SOS1):c.1655G>C (p.Arg552Thr)	rs397517154
NM_005633.4(SOS1):c.1655G>T (p.Arg552Met)	rs397517154
NM_005633.4(SOS1):c.1656G>C (p.Arg552Ser)	rs267607079
NM_005633.4(SOS1):c.1656G>T (p.Arg552Ser)	rs267607079
NM_005633.4(SOS1):c.1867T>G (p.Phe623Val)	rs727505093
NM_005633.4(SOS1):c.2104T>C (p.Tyr702His)	rs727505381
NM_005633.4(SOS1):c.2183A>T (p.Lys728Ile)	rs397517156
NM_005633.4(SOS1):c.2197A>T (p.Ile733Phe)	rs574088829
NM_005633.4(SOS1):c.2536G>A (p.Glu846Lys)	rs397517159
NM_005633.4(SOS1):c.253T>C (p.Trp85Arg)	rs730881054
NM_005633.4(SOS1):c.2894C>G (p.Ala965Gly)
NM_005633.4(SOS1):c.305C>G (p.Pro102Arg)	rs1553362937
NM_005633.4(SOS1):c.322G>A (p.Glu108Lys)	rs397517164
NM_005633.4(SOS1):c.508A>G (p.Lys170Glu)	rs397517172
NM_005633.4(SOS1):c.797C>A (p.Thr266Lys)	rs137852812
NM_005633.4(SOS1):c.806T>C (p.Met269Thr)	rs137852813
NM_005633.4(SOS1):c.806T>G (p.Met269Arg)	rs137852813
NM_005633.4(SOS1):c.925G>T (p.Asp309Tyr)	rs397517180

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