List of variants in gene SPRED1 reported as uncertain significance

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 202

Download table as spreadsheet

HGVS	dbSNP
GRCh37/hg19 15q14(chr15:38533577-38587586)x3
NM_152594.3(SPRED1):c.*105A>G
NM_152594.3(SPRED1):c.*1095A>G
NM_152594.3(SPRED1):c.*1337A>C	rs570038934
NM_152594.3(SPRED1):c.*1400G>A	rs886051109
NM_152594.3(SPRED1):c.*149G>A	rs776485386
NM_152594.3(SPRED1):c.*1563C>T	rs886051110
NM_152594.3(SPRED1):c.*1727G>T
NM_152594.3(SPRED1):c.*1747A>C	rs561525888
NM_152594.3(SPRED1):c.*1798A>C	rs886051111
NM_152594.3(SPRED1):c.*1833A>C
NM_152594.3(SPRED1):c.*1897C>T	rs776375597
NM_152594.3(SPRED1):c.*1967C>T
NM_152594.3(SPRED1):c.*2117A>G
NM_152594.3(SPRED1):c.*2251G>A
NM_152594.3(SPRED1):c.*2323T>C
NM_152594.3(SPRED1):c.*2359G>C	rs886051112
NM_152594.3(SPRED1):c.*2398T>G
NM_152594.3(SPRED1):c.*2414del	rs532033889
NM_152594.3(SPRED1):c.*2420T>C
NM_152594.3(SPRED1):c.*2422A>G
NM_152594.3(SPRED1):c.*2444T>A
NM_152594.3(SPRED1):c.2506_2513del	rs770258605
NM_152594.3(SPRED1):c.*2539A>T
NM_152594.3(SPRED1):c.*2843A>C	rs886051115
NM_152594.3(SPRED1):c.*2853A>G
NM_152594.3(SPRED1):c.*2990T>C
NM_152594.3(SPRED1):c.*3192G>A	rs566065329
NM_152594.3(SPRED1):c.*3289C>T
NM_152594.3(SPRED1):c.*3323C>T
NM_152594.3(SPRED1):c.*3340G>A
NM_152594.3(SPRED1):c.*3395G>A
NM_152594.3(SPRED1):c.*3536C>G
NM_152594.3(SPRED1):c.*3543C>T
NM_152594.3(SPRED1):c.*3544G>A	rs886051116
NM_152594.3(SPRED1):c.*3584G>A	rs886051117
NM_152594.3(SPRED1):c.*3647T>G	rs186366365
NM_152594.3(SPRED1):c.*3657C>T
NM_152594.3(SPRED1):c.*3659A>G
NM_152594.3(SPRED1):c.*3701A>G
NM_152594.3(SPRED1):c.*3705A>G
NM_152594.3(SPRED1):c.*3745A>G
NM_152594.3(SPRED1):c.*383G>A
NM_152594.3(SPRED1):c.*4046G>A	rs886051118
NM_152594.3(SPRED1):c.4136_4138ATT[1]	rs369376164
NM_152594.3(SPRED1):c.*4304G>A
NM_152594.3(SPRED1):c.*4471C>A
NM_152594.3(SPRED1):c.*4472C>A	rs541556786
NM_152594.3(SPRED1):c.*4725A>G	rs530058944
NM_152594.3(SPRED1):c.*4744G>T	rs886051120
NM_152594.3(SPRED1):c.*4781C>A	rs886051121
NM_152594.3(SPRED1):c.*4822A>G	rs576136057
NM_152594.3(SPRED1):c.4948_4949AT[1]	rs886051122
NM_152594.3(SPRED1):c.*4987A>C	rs886051123
NM_152594.3(SPRED1):c.*5232G>A	rs886051124
NM_152594.3(SPRED1):c.*5263C>A
NM_152594.3(SPRED1):c.*5346A>C	rs886051125
NM_152594.3(SPRED1):c.*5418A>G
NM_152594.3(SPRED1):c.*5440T>C
NM_152594.3(SPRED1):c.*5449A>G
NM_152594.3(SPRED1):c.*5540A>G
NM_152594.3(SPRED1):c.*565A>C	rs866578422
NM_152594.3(SPRED1):c.578_579AT[11]	rs147547509
NM_152594.3(SPRED1):c.578_579AT[12]	rs147547509
NM_152594.3(SPRED1):c.578_579AT[13]	rs147547509
NM_152594.3(SPRED1):c.578_579AT[8]	rs147547509
NM_152594.3(SPRED1):c.*632C>T
NM_152594.3(SPRED1):c.*810A>G	rs886051108
NM_152594.3(SPRED1):c.*936C>A
NM_152594.3(SPRED1):c.-114G>A
NM_152594.3(SPRED1):c.-12G>C
NM_152594.3(SPRED1):c.-12G>T	rs371200183
NM_152594.3(SPRED1):c.-152C>A	rs886051102
NM_152594.3(SPRED1):c.-175G>T
NM_152594.3(SPRED1):c.-18G>T	rs755489788
NM_152594.3(SPRED1):c.-201G>A	rs770231868
NM_152594.3(SPRED1):c.-22A>C	rs1057518143
NM_152594.3(SPRED1):c.-24A>G
NM_152594.3(SPRED1):c.-294C>T	rs886051100
NM_152594.3(SPRED1):c.-309C>T	rs578173447
NM_152594.3(SPRED1):c.-87C>T	rs886051103
NM_152594.3(SPRED1):c.1000C>T (p.Arg334Cys)	rs765603808
NM_152594.3(SPRED1):c.1001G>A (p.Arg334His)
NM_152594.3(SPRED1):c.1006G>A (p.Val336Ile)	rs373477920
NM_152594.3(SPRED1):c.1031A>G (p.His344Arg)	rs376679136
NM_152594.3(SPRED1):c.1076T>A (p.Ile359Asn)	rs763738243
NM_152594.3(SPRED1):c.1085G>A (p.Cys362Tyr)
NM_152594.3(SPRED1):c.1098T>G (p.Val366=)
NM_152594.3(SPRED1):c.1103G>C (p.Cys368Ser)
NM_152594.3(SPRED1):c.1108C>T (p.Leu370Phe)	rs397517870
NM_152594.3(SPRED1):c.1119G>T (p.Glu373Asp)	rs1085307754
NM_152594.3(SPRED1):c.115C>G (p.Leu39Val)	rs1555389691
NM_152594.3(SPRED1):c.1163C>T (p.Ser388Phe)
NM_152594.3(SPRED1):c.1189G>A (p.Asp397Asn)
NM_152594.3(SPRED1):c.118AGC[1] (p.Ser41del)
NM_152594.3(SPRED1):c.1202G>T (p.Cys401Phe)	rs779058019
NM_152594.3(SPRED1):c.1217C>T (p.Ala406Val)
NM_152594.3(SPRED1):c.1225_1226delinsTT (p.Ala409Phe)	rs1566877075
NM_152594.3(SPRED1):c.1246T>C (p.Cys416Arg)
NM_152594.3(SPRED1):c.124G>A (p.Val42Ile)	rs147204964
NM_152594.3(SPRED1):c.1280A>G (p.His427Arg)
NM_152594.3(SPRED1):c.1281_*4dup (p.His427_Ter445=)
NM_152594.3(SPRED1):c.1282C>T (p.Arg428Cys)	rs941091989
NM_152594.3(SPRED1):c.1283G>A (p.Arg428His)	rs369492789
NM_152594.3(SPRED1):c.1289G>C (p.Gly430Ala)	rs749389617
NM_152594.3(SPRED1):c.1295C>T (p.Ala432Val)	rs200871227
NM_152594.3(SPRED1):c.1298G>A (p.Cys433Tyr)
NM_152594.3(SPRED1):c.1301G>T (p.Gly434Val)	rs746414913
NM_152594.3(SPRED1):c.1313G>T (p.Gly438Val)
NM_152594.3(SPRED1):c.1324G>A (p.Ala442Thr)
NM_152594.3(SPRED1):c.135C>G (p.Phe45Leu)	rs1595733562
NM_152594.3(SPRED1):c.149A>T (p.Gln50Leu)	rs1475256958
NM_152594.3(SPRED1):c.161G>T (p.Gly54Val)
NM_152594.3(SPRED1):c.170A>G (p.Asp57Gly)
NM_152594.3(SPRED1):c.178A>G (p.Ile60Val)	rs761830220
NM_152594.3(SPRED1):c.181C>T (p.Arg61Cys)	rs765788978
NM_152594.3(SPRED1):c.182G>A (p.Arg61His)	rs750686148
NM_152594.3(SPRED1):c.196A>C (p.Arg66=)	rs751923342
NM_152594.3(SPRED1):c.197G>C (p.Arg66Thr)
NM_152594.3(SPRED1):c.211G>A (p.Val71Ile)
NM_152594.3(SPRED1):c.221G>T (p.Cys74Phe)	rs1412213561
NM_152594.3(SPRED1):c.26A>T (p.Asp9Val)	rs200157475
NM_152594.3(SPRED1):c.274T>C (p.Trp92Arg)	rs1566867214
NM_152594.3(SPRED1):c.281T>C (p.Ile94Thr)	rs761473300
NM_152594.3(SPRED1):c.287A>G (p.Asp96Gly)	rs1555391039
NM_152594.3(SPRED1):c.299G>A (p.Gly100Asp)	rs1555391048
NM_152594.3(SPRED1):c.29A>G (p.Asn10Ser)
NM_152594.3(SPRED1):c.302T>C (p.Leu101Pro)	rs1595746820
NM_152594.3(SPRED1):c.302T>G (p.Leu101Arg)	rs1595746820
NM_152594.3(SPRED1):c.305C>A (p.Thr102Lys)
NM_152594.3(SPRED1):c.305C>G (p.Thr102Arg)	rs754706111
NM_152594.3(SPRED1):c.315T>G (p.Ser105Arg)	rs1566867263
NM_152594.3(SPRED1):c.31G>A (p.Asp11Asn)
NM_152594.3(SPRED1):c.32+3A>T
NM_152594.3(SPRED1):c.353G>A (p.Arg118Lys)
NM_152594.3(SPRED1):c.353G>C (p.Arg118Thr)
NM_152594.3(SPRED1):c.371C>T (p.Ser124Phe)
NM_152594.3(SPRED1):c.376+3A>T	rs775985211
NM_152594.3(SPRED1):c.376+9T>G	rs1555391063
NM_152594.3(SPRED1):c.382C>G (p.Pro128Ala)
NM_152594.3(SPRED1):c.38G>A (p.Ser13Asn)	rs1057517922
NM_152594.3(SPRED1):c.395A>G (p.Asn132Ser)	rs1595748117
NM_152594.3(SPRED1):c.401C>G (p.Ala134Gly)	rs762633609
NM_152594.3(SPRED1):c.403G>C (p.Glu135Gln)	rs1595748136
NM_152594.3(SPRED1):c.406G>A (p.Gly136Arg)	rs1555391158
NM_152594.3(SPRED1):c.410C>T (p.Ala137Val)
NM_152594.3(SPRED1):c.421C>A (p.Gln141Lys)
NM_152594.3(SPRED1):c.423+5G>A
NM_152594.3(SPRED1):c.423+5_423+8del
NM_152594.3(SPRED1):c.424-4A>G	rs1057518328
NM_152594.3(SPRED1):c.424-5A>G	rs752656697
NM_152594.3(SPRED1):c.431A>G (p.Glu144Gly)
NM_152594.3(SPRED1):c.449C>T (p.Ser150Phe)	rs1555392025
NM_152594.3(SPRED1):c.451C>G (p.Leu151Val)
NM_152594.3(SPRED1):c.462_464dup (p.His155dup)
NM_152594.3(SPRED1):c.477A>T (p.Gln159His)
NM_152594.3(SPRED1):c.47G>A (p.Arg16Gln)
NM_152594.3(SPRED1):c.487G>T (p.Val163Phe)
NM_152594.3(SPRED1):c.49G>A (p.Val17Met)
NM_152594.3(SPRED1):c.502T>G (p.Tyr168Asp)
NM_152594.3(SPRED1):c.511T>C (p.Ser171Pro)
NM_152594.3(SPRED1):c.517A>G (p.Ile173Val)	rs1060502504
NM_152594.3(SPRED1):c.535G>A (p.Glu179Lys)
NM_152594.3(SPRED1):c.538G>T (p.Asp180Tyr)	rs1375474473
NM_152594.3(SPRED1):c.563T>C (p.Met188Thr)
NM_152594.3(SPRED1):c.564G>A (p.Met188Ile)	rs202092705
NM_152594.3(SPRED1):c.565C>A (p.Gln189Lys)	rs200142785
NM_152594.3(SPRED1):c.582+16A>G
NM_152594.3(SPRED1):c.583-9G>T
NM_152594.3(SPRED1):c.583A>T (p.Ile195Leu)
NM_152594.3(SPRED1):c.587C>T (p.Thr196Ile)	rs147474792
NM_152594.3(SPRED1):c.605T>C (p.Leu202Ser)	rs1555392598
NM_152594.3(SPRED1):c.640C>T (p.Arg214Trp)
NM_152594.3(SPRED1):c.641G>A (p.Arg214Gln)
NM_152594.3(SPRED1):c.659G>A (p.Cys220Tyr)
NM_152594.3(SPRED1):c.666C>A (p.Ser222Arg)
NM_152594.3(SPRED1):c.66G>T (p.Met22Ile)	rs1555389685
NM_152594.3(SPRED1):c.683G>A (p.Arg228Lys)	rs951963194
NM_152594.3(SPRED1):c.684+50A>T	rs200338097
NM_152594.3(SPRED1):c.685G>T (p.Val229Phe)	rs201837340
NM_152594.3(SPRED1):c.6C>A (p.Ser2Arg)
NM_152594.3(SPRED1):c.707A>G (p.His236Arg)	rs886051104
NM_152594.3(SPRED1):c.747C>G (p.Asn249Lys)
NM_152594.3(SPRED1):c.74A>G (p.Asp25Gly)	rs1057524159
NM_152594.3(SPRED1):c.770G>A (p.Arg257His)
NM_152594.3(SPRED1):c.807T>G (p.Asn269Lys)	rs886041428
NM_152594.3(SPRED1):c.836G>A (p.Ser279Asn)
NM_152594.3(SPRED1):c.842A>G (p.Gln281Arg)	rs1427402192
NM_152594.3(SPRED1):c.854C>T (p.Pro285Leu)
NM_152594.3(SPRED1):c.881A>T (p.Tyr294Phe)	rs886051105
NM_152594.3(SPRED1):c.886T>C (p.Cys296Arg)	rs554327738
NM_152594.3(SPRED1):c.892G>C (p.Asp298His)
NM_152594.3(SPRED1):c.917A>G (p.Lys306Arg)
NM_152594.3(SPRED1):c.920A>G (p.Asp307Gly)
NM_152594.3(SPRED1):c.922T>A (p.Ser308Thr)
NM_152594.3(SPRED1):c.926T>C (p.Val309Ala)	rs114636635
NM_152594.3(SPRED1):c.944C>T (p.Pro315Leu)	rs115440602
NM_152594.3(SPRED1):c.963G>A (p.Lys321=)	rs369711772
NM_152594.3(SPRED1):c.973C>G (p.Arg325Gly)
NM_152594.3(SPRED1):c.974G>A (p.Arg325Gln)	rs1238094530
NM_152594.3(SPRED1):c.982G>A (p.Glu328Lys)
NM_152594.3(SPRED1):c.995G>A (p.Arg332His)	rs779966392

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.