ClinVar Miner

Variants in gene TG

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Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign risk factor not provided total
27 15 223 108 90 4 1 379

Condition and significance breakdown #

Total conditions: 11
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Condition pathogenic likely pathogenic uncertain significance likely benign benign risk factor not provided total
Iodotyrosyl coupling defect 22 2 211 25 21 0 0 277
not provided 4 7 14 75 69 0 0 168
not specified 0 0 4 8 13 0 0 25
Congenital hypothyroidism 6 4 0 1 1 0 1 13
Autoimmune thyroid disease 3 1 1 0 0 0 4 0 6
Thyroid dyshormonogenesis 0 0 2 0 0 0 0 2
Hereditary breast and ovarian cancer syndrome 0 0 1 0 0 0 0 1
Hypothyroidism 0 1 0 0 0 0 0 1
Iodotyrosyl coupling defect; Autoimmune thyroid disease 3 0 0 1 0 0 0 0 1
Malignant tumor of prostate 0 0 1 0 0 0 0 1
Premature ovarian failure 0 0 1 0 0 0 0 1

Submitter and significance breakdown #

Total submitters: 28
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Submitter pathogenic likely pathogenic uncertain significance likely benign benign risk factor not provided total
Illumina Clinical Services Laboratory,Illumina 1 0 205 25 20 0 0 251
Invitae 0 1 0 74 69 0 0 144
OMIM 14 0 1 0 0 4 0 19
PreventionGenetics, PreventionGenetics 0 0 0 5 13 0 0 18
GeneDx 3 5 6 1 0 0 0 15
Polak associated Lab,IMAGINE Institute 6 4 0 1 1 0 0 12
Baylor Genetics 3 0 5 0 0 0 0 8
Genetic Services Laboratory, University of Chicago 1 0 4 2 0 0 0 7
CeGaT Praxis fuer Humangenetik Tuebingen 0 1 3 1 0 0 0 5
Mendelics 0 0 2 0 1 0 0 3
EGL Genetic Diagnostics, Eurofins Clinical Diagnostics 2 0 1 0 0 0 0 3
Laboratory for Molecular Medicine,Partners HealthCare Personalized Medicine 1 0 1 0 0 0 0 2
Center for Pediatric Genomic Medicine,Children's Mercy Hospital and Clinics 0 0 2 0 0 0 0 2
Department of Pathology and Laboratory Medicine,Sinai Health System 0 0 2 0 0 0 0 2
Department of Pediatrics, Division of Medical Genetics, Faculty of Medicine Ramathibodi Hospital, Mahidol University 1 1 0 0 0 0 0 2
Fulgent Genetics,Fulgent Genetics 0 0 1 0 0 0 0 1
Science for Life laboratory, Karolinska Institutet 0 0 1 0 0 0 0 1
Division of Human Genetics,Children's Hospital of Philadelphia 1 0 0 0 0 0 0 1
Lupski Lab, Baylor-Hopkins CMG, Baylor College of Medicine 0 0 1 0 0 0 0 1
Pediatric Genetics Division, Center for Pediatrics and Adolescent Medicine,University Medical Center Freiburg 1 0 0 0 0 0 0 1
Soonchunhyang University Bucheon Hospital,Soonchunhyang University Medical Center 0 0 1 0 0 0 0 1
Institute of Human Genetics,University of Wuerzburg 0 1 0 0 0 0 0 1
Yale Center for Mendelian Genomics,Yale University 0 1 0 0 0 0 0 1
GenomeConnect, ClinGen 0 0 0 0 0 0 1 1
Biochemical Molecular Genetic Laboratory,King Abdulaziz Medical City 0 1 0 0 0 0 0 1
Center for Precision Medicine,Vanderbilt University Medical Center 1 0 0 0 0 0 0 1
Weiss Lab,University of Miami 1 0 0 0 0 0 0 1
Molecular Oncology Research Center,Barretos Cancer Hospital 0 0 1 0 0 0 0 1

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