ClinVar Miner

List of variants in gene TP53 reported as likely benign for Hereditary cancer-predisposing syndrome

Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:
Total variants: 315
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HGVS dbSNP
NM_000546.5(TP53):c.*1175A>C rs78378222
NM_000546.5(TP53):c.-12C>T rs375229869
NM_000546.5(TP53):c.1002G>A (p.Gly334=) rs786203531
NM_000546.5(TP53):c.1008G>A (p.Glu336=) rs1555524453
NM_000546.5(TP53):c.100C>A (p.Pro34Thr) rs786201968
NM_000546.5(TP53):c.1014C>T (p.Phe338=) rs150293825
NM_000546.5(TP53):c.1015G>A (p.Glu339Lys) rs17882252
NM_000546.5(TP53):c.1023C>T (p.Phe341=) rs864622369
NM_000546.5(TP53):c.102C>G (p.Pro34=) rs11575998
NM_000546.5(TP53):c.1038G>A (p.Glu346=) rs1555524406
NM_000546.5(TP53):c.1041C>G (p.Ala347=) rs1450229137
NM_000546.5(TP53):c.1062G>A (p.Gln354=) rs1382535379
NM_000546.5(TP53):c.1077A>G (p.Pro359=) rs539224556
NM_000546.5(TP53):c.1079G>C (p.Gly360Ala) rs35993958
NM_000546.5(TP53):c.1079G>T (p.Gly360Val) rs35993958
NM_000546.5(TP53):c.108G>A (p.Pro36=) rs1800370
NM_000546.5(TP53):c.1096T>G (p.Ser366Ala) rs17881470
NM_000546.5(TP53):c.1100+12C>G rs1567541617
NM_000546.5(TP53):c.1100+15C>T rs1555524333
NM_000546.5(TP53):c.1100+8A>G rs878854062
NM_000546.5(TP53):c.1104C>T (p.His368=) rs1289241865
NM_000546.5(TP53):c.1110G>A (p.Lys370=) rs1567540533
NM_000546.5(TP53):c.1119G>A (p.Lys373=) rs1342613419
NM_000546.5(TP53):c.111C>G (p.Ser37=) rs1555526798
NM_000546.5(TP53):c.1120G>A (p.Gly374Ser) rs587781858
NM_000546.5(TP53):c.1120G>C (p.Gly374Arg) rs587781858
NM_000546.5(TP53):c.1125G>A (p.Gln375=) rs764011631
NM_000546.5(TP53):c.1137C>T (p.Arg379=) rs786202368
NM_000546.5(TP53):c.1149C>A (p.Leu383=) rs373710656
NM_000546.5(TP53):c.1149C>T (p.Leu383=) rs373710656
NM_000546.5(TP53):c.1160C>G (p.Thr387Arg) rs927888647
NM_000546.5(TP53):c.1161A>G (p.Thr387=) rs1131691017
NM_000546.5(TP53):c.123T>C (p.Asp41=) rs369129220
NM_000546.5(TP53):c.12G>A (p.Pro4=) rs876658274
NM_000546.5(TP53):c.141G>A (p.Pro47=) rs201741778
NM_000546.5(TP53):c.144C>T (p.Asp48=) rs587781460
NM_000546.5(TP53):c.145G>A (p.Asp49Asn) rs587780728
NM_000546.5(TP53):c.147T>C (p.Asp49=) rs786201148
NM_000546.5(TP53):c.160T>C (p.Phe54Leu) rs1555526742
NM_000546.5(TP53):c.168A>G (p.Glu56=) rs574255227
NM_000546.5(TP53):c.171C>T (p.Asp57=) rs587782776
NM_000546.5(TP53):c.173C>G (p.Pro58Arg) rs144386518
NM_000546.5(TP53):c.180A>C (p.Pro60=) rs749289195
NM_000546.5(TP53):c.18A>C (p.Ser6=) rs573130482
NM_000546.5(TP53):c.18A>G (p.Ser6=) rs573130482
NM_000546.5(TP53):c.192C>G (p.Pro64=) rs1555526723
NM_000546.5(TP53):c.193A>C (p.Arg65=) rs1555526721
NM_000546.5(TP53):c.201A>G (p.Pro67=) rs786203912
NM_000546.5(TP53):c.204G>A (p.Glu68=) rs746814615
NM_000546.5(TP53):c.206C>G (p.Ala69Gly) rs756233241
NM_000546.5(TP53):c.210T>A (p.Ala70=) rs786203513
NM_000546.5(TP53):c.210T>C (p.Ala70=) rs786203513
NM_000546.5(TP53):c.216C>T (p.Pro72=) rs56275308
NM_000546.5(TP53):c.217G>A (p.Val73Met) rs587782423
NM_000546.5(TP53):c.21T>A (p.Asp7Glu) rs587781277
NM_000546.5(TP53):c.21T>G (p.Asp7Glu) rs587781277
NM_000546.5(TP53):c.222C>T (p.Ala74=) rs786201577
NM_000546.5(TP53):c.234A>G (p.Ala78=) rs375099397
NM_000546.5(TP53):c.23C>T (p.Pro8Leu) rs876659415
NM_000546.5(TP53):c.246G>A (p.Pro82=) rs372397095
NM_000546.5(TP53):c.248C>T (p.Ala83Val) rs201717599
NM_000546.5(TP53):c.249G>A (p.Ala83=) rs55754907
NM_000546.5(TP53):c.255T>A (p.Pro85=) rs775515332
NM_000546.5(TP53):c.255T>C (p.Pro85=) rs775515332
NM_000546.5(TP53):c.256G>A (p.Ala86Thr) rs587782148
NM_000546.5(TP53):c.264C>T (p.Ala88=) rs876660951
NM_000546.5(TP53):c.267C>T (p.Pro89=) rs786201443
NM_000546.5(TP53):c.270C>T (p.Ser90=) rs863224370
NM_000546.5(TP53):c.276C>T (p.Pro92=) rs876658845
NM_000546.5(TP53):c.277C>T (p.Leu93=) rs876658561
NM_000546.5(TP53):c.279G>T (p.Leu93=) rs878854067
NM_000546.5(TP53):c.27C>T (p.Ser9=) rs757282628
NM_000546.5(TP53):c.282A>G (p.Ser94=) rs771721337
NM_000546.5(TP53):c.285T>G (p.Ser95=) rs876658696
NM_000546.5(TP53):c.28G>A (p.Val10Ile) rs535274413
NM_000546.5(TP53):c.297C>T (p.Ser99=) rs751494750
NM_000546.5(TP53):c.30C>T (p.Val10=) rs568171603
NM_000546.5(TP53):c.319T>C (p.Tyr107His) rs368771578
NM_000546.5(TP53):c.31G>A (p.Glu11Lys) rs201382018
NM_000546.5(TP53):c.31G>C (p.Glu11Gln) rs201382018
NM_000546.5(TP53):c.321C>T (p.Tyr107=) rs770776262
NM_000546.5(TP53):c.336C>A (p.Gly112=) rs876659177
NM_000546.5(TP53):c.345T>C (p.His115=) rs1555526530
NM_000546.5(TP53):c.351G>A (p.Gly117=) rs876658998
NM_000546.5(TP53):c.354A>T (p.Thr118=) rs751978853
NM_000546.5(TP53):c.363T>G (p.Ser121=) rs1567555531
NM_000546.5(TP53):c.375+13G>A rs758658664
NM_000546.5(TP53):c.375+18G>A rs1567555404
NM_000546.5(TP53):c.376-17C>T rs376713749
NM_000546.5(TP53):c.376-18dup rs756417643
NM_000546.5(TP53):c.376-19C>T rs1057521606
NM_000546.5(TP53):c.376-20T>C rs1483487754
NM_000546.5(TP53):c.376-4A>T rs1221388024
NM_000546.5(TP53):c.384T>C (p.Pro128=) rs1555526324
NM_000546.5(TP53):c.385G>A (p.Ala129Thr) rs1438095083
NM_000546.5(TP53):c.390C>T (p.Leu130=) rs781537596
NM_000546.5(TP53):c.39T>G (p.Pro13=) rs1555527000
NM_000546.5(TP53):c.402T>C (p.Phe134=) rs1555526278
NM_000546.5(TP53):c.405C>T (p.Cys135=) rs1057519976
NM_000546.5(TP53):c.408A>G (p.Gln136=) rs758781593
NM_000546.5(TP53):c.411G>C (p.Leu137=) rs876660731
NM_000546.5(TP53):c.414C>T (p.Ala138=) rs1555526254
NM_000546.5(TP53):c.42G>C (p.Leu14=) rs773918872
NM_000546.5(TP53):c.432G>A (p.Gln144=) rs786201419
NM_000546.5(TP53):c.433C>T (p.Leu145=) rs786203928
NM_000546.5(TP53):c.450A>G (p.Thr150=) rs754020850
NM_000546.5(TP53):c.456G>A (p.Pro152=) rs876659481
NM_000546.5(TP53):c.459C>T (p.Pro153=) rs72661116
NM_000546.5(TP53):c.45T>C (p.Ser15=) rs766765429
NM_000546.5(TP53):c.464C>G (p.Thr155Ser) rs786202752
NM_000546.5(TP53):c.465C>A (p.Thr155=) rs786202992
NM_000546.5(TP53):c.466C>T (p.Arg156Cys) rs563378859
NM_000546.5(TP53):c.468C>T (p.Arg156=) rs761222871
NM_000546.5(TP53):c.471C>A (p.Val157=) rs1057522496
NM_000546.5(TP53):c.474C>T (p.Arg158=) rs139200646
NM_000546.5(TP53):c.478A>G (p.Met160Val) rs377274728
NM_000546.5(TP53):c.483C>A (p.Ala161=) rs1057523101
NM_000546.5(TP53):c.492G>A (p.Lys164=) rs1131691034
NM_000546.5(TP53):c.493C>A (p.Gln165Lys) rs730882001
NM_000546.5(TP53):c.498A>G (p.Ser166=) rs1555526098
NM_000546.5(TP53):c.504C>T (p.His168=) rs746293837
NM_000546.5(TP53):c.510G>A (p.Thr170=) rs757544615
NM_000546.5(TP53):c.513G>A (p.Glu171=) rs1555526078
NM_000546.5(TP53):c.534C>T (p.His178=) rs1555526001
NM_000546.5(TP53):c.537T>C (p.His179=) rs876660821
NM_000546.5(TP53):c.543C>T (p.Arg181=) rs876659582
NM_000546.5(TP53):c.54A>G (p.Thr18=) rs876659984
NM_000546.5(TP53):c.555C>T (p.Ser185=) rs367560109
NM_000546.5(TP53):c.558T>A (p.Asp186Glu) rs375275361
NM_000546.5(TP53):c.558T>C (p.Asp186=) rs375275361
NM_000546.5(TP53):c.559+13G>A rs56226808
NM_000546.5(TP53):c.559+20G>A rs547244762
NM_000546.5(TP53):c.559+9C>G rs1224204682
NM_000546.5(TP53):c.560-14C>A rs1567552335
NM_000546.5(TP53):c.560-15A>C rs1555525938
NM_000546.5(TP53):c.560-8G>C rs373797299
NM_000546.5(TP53):c.567C>T (p.Ala189=) rs55764374
NM_000546.5(TP53):c.582T>C (p.Leu194=) rs370216745
NM_000546.5(TP53):c.585C>A (p.Ile195=) rs1057519994
NM_000546.5(TP53):c.604C>T (p.Arg202Cys) rs587780072
NM_000546.5(TP53):c.605G>A (p.Arg202His) rs587778719
NM_000546.5(TP53):c.606T>C (p.Arg202=) rs1392931620
NM_000546.5(TP53):c.60A>G (p.Ser20=) rs786201754
NM_000546.5(TP53):c.612G>A (p.Glu204=) rs749629973
NM_000546.5(TP53):c.617T>C (p.Leu206Ser) rs1555525804
NM_000546.5(TP53):c.618G>A (p.Leu206=) rs142813240
NM_000546.5(TP53):c.630C>T (p.Asn210=) rs1555525791
NM_000546.5(TP53):c.639A>G (p.Arg213=) rs1800372
NM_000546.5(TP53):c.63C>T (p.Asp21=) rs1800369
NM_000546.5(TP53):c.642T>G (p.His214Gln) rs587781386
NM_000546.5(TP53):c.645T>C (p.Ser215=) rs1057520001
NM_000546.5(TP53):c.648G>A (p.Val216=) rs199693249
NM_000546.5(TP53):c.651G>T (p.Val217=) rs1555525747
NM_000546.5(TP53):c.654G>A (p.Val218=) rs753630563
NM_000546.5(TP53):c.657C>A (p.Pro219=) rs786201859
NM_000546.5(TP53):c.664C>T (p.Pro222Ser) rs1060501203
NM_000546.5(TP53):c.666G>A (p.Pro222=) rs72661118
NM_000546.5(TP53):c.666G>T (p.Pro222=) rs72661118
NM_000546.5(TP53):c.66A>G (p.Leu22=) rs748527030
NM_000546.5(TP53):c.672+14C>G rs1555525697
NM_000546.5(TP53):c.672+15T>C rs140756213
NM_000546.5(TP53):c.672+16G>A rs1555525695
NM_000546.5(TP53):c.672+18G>C rs199578278
NM_000546.5(TP53):c.672+19G>A rs1385638165
NM_000546.5(TP53):c.673-13T>C rs1555525587
NM_000546.5(TP53):c.673-19G>A rs564974117
NM_000546.5(TP53):c.673-3T>C rs1214646363
NM_000546.5(TP53):c.673-5C>A rs876658684
NM_000546.5(TP53):c.673-9A>G rs754628512
NM_000546.5(TP53):c.673-9del rs762540407
NM_000546.5(TP53):c.675T>C (p.Val225=) rs1555525584
NM_000546.5(TP53):c.681T>G (p.Ser227=) rs1555525574
NM_000546.5(TP53):c.696C>T (p.Ile232=) rs786202888
NM_000546.5(TP53):c.6G>A (p.Glu2=) rs143458271
NM_000546.5(TP53):c.704A>G (p.Asn235Ser) rs144340710
NM_000546.5(TP53):c.717C>T (p.Asn239=) rs1057522275
NM_000546.5(TP53):c.732C>T (p.Gly244=) rs759625762
NM_000546.5(TP53):c.73C>T (p.Leu25=) rs1555526988
NM_000546.5(TP53):c.74+14T>C rs184743157
NM_000546.5(TP53):c.74+22G>A rs780218773
NM_000546.5(TP53):c.74+27C>G rs1555526978
NM_000546.5(TP53):c.74+27_74+29del rs1167199080
NM_000546.5(TP53):c.74+32C>G rs1567557970
NM_000546.5(TP53):c.74+34C>A rs758434025
NM_000546.5(TP53):c.74+35C>T rs984971583
NM_000546.5(TP53):c.74+37C>T rs749212949
NM_000546.5(TP53):c.74+39_74+56dup rs1567557864
NM_000546.5(TP53):c.74+41C>T rs752547878
NM_000546.5(TP53):c.74+44A>G rs377074538
NM_000546.5(TP53):c.74+54C>T rs1567557870
NM_000546.5(TP53):c.74+56C>G rs1555526957
NM_000546.5(TP53):c.74+57del rs1555526956
NM_000546.5(TP53):c.74+59G>C rs1555526955
NM_000546.5(TP53):c.74+8G>A rs776933919
NM_000546.5(TP53):c.741C>T (p.Asn247=) rs786202448
NM_000546.5(TP53):c.75-12C>A rs1051425969
NM_000546.5(TP53):c.75-14C>T rs747908393
NM_000546.5(TP53):c.75-17C>A rs910296194
NM_000546.5(TP53):c.75-18T>G rs1273569924
NM_000546.5(TP53):c.75-27G>A rs943163238
NM_000546.5(TP53):c.75-30T>C rs368444215
NM_000546.5(TP53):c.75-31A>G rs1567557800
NM_000546.5(TP53):c.75-32C>T rs745951235
NM_000546.5(TP53):c.75-40G>A rs372756865
NM_000546.5(TP53):c.75-41C>T rs569425726
NM_000546.5(TP53):c.75-42G>T rs768964728
NM_000546.5(TP53):c.75-43A>C rs762253412
NM_000546.5(TP53):c.75-47G>A rs765673441
NM_000546.5(TP53):c.75-49G>T rs1555526952
NM_000546.5(TP53):c.75-54G>A rs971879465
NM_000546.5(TP53):c.75-56G>T rs1364767238
NM_000546.5(TP53):c.753C>T (p.Ile251=) rs878854074
NM_000546.5(TP53):c.768A>G (p.Thr256=) rs786203563
NM_000546.5(TP53):c.768A>T (p.Thr256=) rs786203563
NM_000546.5(TP53):c.769C>T (p.Leu257=) rs779761818
NM_000546.5(TP53):c.782+10C>T rs200277687
NM_000546.5(TP53):c.782+12C>T rs17881780
NM_000546.5(TP53):c.782+14T>G rs1437756379
NM_000546.5(TP53):c.782+17C>T rs17880172
NM_000546.5(TP53):c.783-11A>G rs771914358
NM_000546.5(TP53):c.783-33T>C rs113302588
NM_000546.5(TP53):c.783-34C>T rs376988747
NM_000546.5(TP53):c.783-35A>G rs776659879
NM_000546.5(TP53):c.783-47C>G rs1337240615
NM_000546.5(TP53):c.783-52T>G rs774455868
NM_000546.5(TP53):c.783-56C>T rs1567548516
NM_000546.5(TP53):c.783-58G>A rs1343035495
NM_000546.5(TP53):c.783-58G>T rs1343035495
NM_000546.5(TP53):c.783-59G>A rs774077441
NM_000546.5(TP53):c.783-60G>A rs898427453
NM_000546.5(TP53):c.783-62A>G rs1555525379
NM_000546.5(TP53):c.783-64A>C rs995865613
NM_000546.5(TP53):c.783-66T>G rs1555525382
NM_000546.5(TP53):c.783-78del rs1555525386
NM_000546.5(TP53):c.789T>C (p.Asn263=) rs770598448
NM_000546.5(TP53):c.78T>C (p.Leu26=) rs934176141
NM_000546.5(TP53):c.798A>T (p.Gly266=) rs1555525321
NM_000546.5(TP53):c.837G>A (p.Gly279=) rs786201322
NM_000546.5(TP53):c.846G>A (p.Arg282=) rs1555525211
NM_000546.5(TP53):c.852A>C (p.Thr284=) rs786203004
NM_000546.5(TP53):c.855G>A (p.Glu285=) rs1487868349
NM_000546.5(TP53):c.867C>T (p.Leu289=) rs778138282
NM_000546.5(TP53):c.883C>T (p.Pro295Ser) rs1131691006
NM_000546.5(TP53):c.885T>C (p.Pro295=) rs200073907
NM_000546.5(TP53):c.891C>T (p.His297=) rs750578863
NM_000546.5(TP53):c.892G>A (p.Glu298Lys) rs201744589
NM_000546.5(TP53):c.903A>G (p.Pro301=) rs72661120
NM_000546.5(TP53):c.90C>T (p.Asn30=) rs370992294
NM_000546.5(TP53):c.912T>C (p.Thr304=) rs1555525052
NM_000546.5(TP53):c.919+15C>G rs1057523528
NM_000546.5(TP53):c.919+7A>C rs199527475
NM_000546.5(TP53):c.919+9G>A rs772829199
NM_000546.5(TP53):c.91G>A (p.Val31Ile) rs201753350
NM_000546.5(TP53):c.920-13G>C rs1057522354
NM_000546.5(TP53):c.920-14T>C rs752627700
NM_000546.5(TP53):c.920-17C>A rs911934766
NM_000546.5(TP53):c.920-5C>T rs34361146
NM_000546.5(TP53):c.922C>T (p.Leu308=) rs1555525016
NM_000546.5(TP53):c.924G>A (p.Leu308=) rs786202546
NM_000546.5(TP53):c.924G>C (p.Leu308=) rs786202546
NM_000546.5(TP53):c.927C>A (p.Pro309=) rs1393711933
NM_000546.5(TP53):c.931A>C (p.Asn311His) rs1555525007
NM_000546.5(TP53):c.933C>T (p.Asn311=) rs201601993
NM_000546.5(TP53):c.935C>G (p.Thr312Ser) rs145151284
NM_000546.5(TP53):c.93T>G (p.Val31=) rs1406108270
NM_000546.5(TP53):c.94C>T (p.Leu32=) rs1555526920
NM_000546.5(TP53):c.951G>A (p.Gln317=) rs1060501199
NM_000546.5(TP53):c.96+12G>C rs779577884
NM_000546.5(TP53):c.96+25_96+34del rs1555526882
NM_000546.5(TP53):c.96+25_97-54del rs59758982
NM_000546.5(TP53):c.96+28_96+31del rs773204149
NM_000546.5(TP53):c.96+31del rs1555526886
NM_000546.5(TP53):c.969G>A (p.Leu323=) rs672601297
NM_000546.5(TP53):c.97-11C>T rs769697802
NM_000546.5(TP53):c.97-6C>T rs35117667
NM_000546.5(TP53):c.97-8A>T rs1555526841
NM_000546.5(TP53):c.97-9C>T rs202217267
NM_000546.5(TP53):c.993+12T>C rs1800899
NM_000546.5(TP53):c.993+13G>C rs369599972
NM_000546.5(TP53):c.993+141G>A rs371592265
NM_000546.5(TP53):c.993+15G>T rs1555524931
NM_000546.5(TP53):c.993+176C>T rs945008591
NM_000546.5(TP53):c.993+177C>T rs1567545538
NM_000546.5(TP53):c.993+189T>A rs758130745
NM_000546.5(TP53):c.993+232G>C rs1470589675
NM_000546.5(TP53):c.993+234G>A rs17883348
NM_000546.5(TP53):c.993+244G>C rs576532147
NM_000546.5(TP53):c.993+245G>A rs978869607
NM_000546.5(TP53):c.993+248C>T rs1555524889
NM_000546.5(TP53):c.993+317G>A rs1245315319
NM_000546.5(TP53):c.993+318T>C rs1567545196
NM_000546.5(TP53):c.993+326_993+341del rs730882013
NM_000546.5(TP53):c.993+331A>G rs1438885967
NM_000546.5(TP53):c.993+7A>G rs1023206153
NM_000546.5(TP53):c.994-12C>T rs1057522329
NM_000546.5(TP53):c.994-17C>T rs368691910
NM_001126113.2(TP53):c.1009C>T (p.Arg337Ter) rs554738122
NM_001126113.2(TP53):c.1010G>A (p.Arg337Gln) rs771319678
NM_001126113.2(TP53):c.1012T>C (p.Trp338Arg) rs749361930
NM_001126113.2(TP53):c.1014G>A (p.Trp338Ter) rs1337983762
NM_001126113.2(TP53):c.1015T>C (p.Cys339Arg) rs1642789
NM_001126113.2(TP53):c.1032C>G (p.Asn344Lys) rs200274944
NM_001126113.2(TP53):c.1034C>T (p.Ser345Leu) rs758194998
NM_001126113.2(TP53):c.1035G>A (p.Ser345=) rs201293647
NM_001126113.2(TP53):c.1035G>T (p.Ser345=) rs201293647
NM_001126113.2(TP53):c.1037C>T (p.Ser346Leu) rs756952434
NM_001126113.2(TP53):c.1038G>A (p.Ser346=) rs372821099
NM_001126113.2(TP53):c.1039dup (p.Ter347LeuextTer?) rs1567545210
NM_001126114.2(TP53):c.1011A>G (p.Gln337=) rs912136376
NM_001126114.2(TP53):c.1014A>C (p.Lys338Asn) rs761303879
NM_001126114.2(TP53):c.1021T>C (p.Cys341Arg) rs3021068
NM_001126114.2(TP53):c.1025A>C (p.Ter342Ser) rs764562217
NM_001126114.2(TP53):c.1026A>G (p.Ter342=) rs761121529
NM_001126114.2(TP53):c.996C>T (p.Asp332=) rs750031971
NM_001126114.2(TP53):c.997C>G (p.Gln333Glu) rs764851816

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