ClinVar Miner

List of variants in gene TP53 reported as pathogenic for Hereditary cancer-predisposing syndrome

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Total variants: 123
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HGVS dbSNP
NM_000546.5(TP53):c.1008_1009GC[1] (p.Arg337fs) rs1131691040
NM_000546.5(TP53):c.1009C>T (p.Arg337Cys) rs587782529
NM_000546.5(TP53):c.1010G>A (p.Arg337His) rs121912664
NM_000546.5(TP53):c.1018del (p.Met340fs) rs1131691005
NM_000546.5(TP53):c.1024C>T (p.Arg342Ter) rs730882029
NM_000546.5(TP53):c.1024del (p.Arg342fs) rs1131691022
NM_000546.5(TP53):c.1049_1050del (p.Leu350fs) rs1131691008
NM_000546.5(TP53):c.1101-2A>G rs587781664
NM_000546.5(TP53):c.121_124dup (p.Asp42delinsGlyTer) rs1555526784
NM_000546.5(TP53):c.137delinsGT (p.Ser46fs) rs587782650
NM_000546.5(TP53):c.155_157dup (p.Trp53Ter) rs587782609
NM_000546.5(TP53):c.158G>A (p.Trp53Ter) rs876658483
NM_000546.5(TP53):c.184G>T (p.Glu62Ter) rs1567556752
NM_000546.5(TP53):c.202G>T (p.Glu68Ter) rs869312782
NM_000546.5(TP53):c.214_215insG (p.Pro72fs) rs1131691014
NM_000546.5(TP53):c.216del (p.Val73fs) rs730882018
NM_000546.5(TP53):c.216dup (p.Val73fs) rs730882018
NM_000546.5(TP53):c.227_279del (p.Ala76fs) rs1555526610
NM_000546.5(TP53):c.248_249del (p.Ala83fs) rs1131691010
NM_000546.5(TP53):c.273G>A (p.Trp91Ter) rs876660548
NM_000546.5(TP53):c.294_297del (p.Ser99fs) rs730882015
NM_000546.5(TP53):c.310_329del (p.Gln104fs) rs1555526565
NM_000546.5(TP53):c.323_329dup (p.Leu111fs) rs1131691004
NM_000546.5(TP53):c.324_328delinsAAAA (p.Phe109fs) rs1131691031
NM_000546.5(TP53):c.326delinsCCCAA (p.Phe109fs) rs1131691038
NM_000546.5(TP53):c.328del (p.Arg110fs) rs587780066
NM_000546.5(TP53):c.375G>A (p.Thr125=) rs55863639
NM_000546.5(TP53):c.391A>T (p.Asn131Tyr) rs587782160
NM_000546.5(TP53):c.394_409del (p.Lys132fs) rs786203589
NM_000546.5(TP53):c.398T>C (p.Met133Thr) rs28934873
NM_000546.5(TP53):c.403_405delinsGG (p.Cys135fs) rs1131691036
NM_000546.5(TP53):c.422G>A (p.Cys141Tyr) rs587781288
NM_000546.5(TP53):c.438G>A (p.Trp146Ter) rs1131691026
NM_000546.5(TP53):c.447_459del (p.Thr150fs) rs137852790
NM_000546.5(TP53):c.454_466del (p.Pro152fs) rs876659215
NM_000546.5(TP53):c.455C>T (p.Pro152Leu) rs587782705
NM_000546.5(TP53):c.455dup (p.Pro153fs) rs730882019
NM_000546.5(TP53):c.473G>A (p.Arg158His) rs587782144
NM_000546.5(TP53):c.488A>G (p.Tyr163Cys) rs148924904
NM_000546.5(TP53):c.493C>T (p.Gln165Ter) rs730882001
NM_000546.5(TP53):c.509_512del (p.Thr170fs) rs1555526082
NM_000546.5(TP53):c.511_515dup (p.Val173fs) rs786202514
NM_000546.5(TP53):c.524G>A (p.Arg175His) rs28934578
NM_000546.5(TP53):c.52del (p.Thr18fs) rs876658627
NM_000546.5(TP53):c.532del (p.His178fs) rs786202525
NM_000546.5(TP53):c.586C>T (p.Arg196Ter) rs397516435
NM_000546.5(TP53):c.58del (p.Ser20fs) rs1131691018
NM_000546.5(TP53):c.592del (p.Glu198fs) rs1131691035
NM_000546.5(TP53):c.599del (p.Asn200fs) rs1131691011
NM_000546.5(TP53):c.615T>A (p.Tyr205Ter) rs786202222
NM_000546.5(TP53):c.626_627del (p.Arg209fs) rs1057517840
NM_000546.5(TP53):c.635_636del (p.Phe212fs) rs864309495
NM_000546.5(TP53):c.637C>T (p.Arg213Ter) rs397516436
NM_000546.5(TP53):c.638G>A (p.Arg213Gln) rs587778720
NM_000546.5(TP53):c.638G>C (p.Arg213Pro) rs587778720
NM_000546.5(TP53):c.651_666del (p.Val218fs) rs786202315
NM_000546.5(TP53):c.655_670del (p.Pro219fs) rs1555525710
NM_000546.5(TP53):c.659A>G (p.Tyr220Cys) rs121912666
NM_000546.5(TP53):c.662del (p.Glu221fs) rs878854071
NM_000546.5(TP53):c.673-1G>A rs878854073
NM_000546.5(TP53):c.685_692del (p.Cys229fs) rs730882016
NM_000546.5(TP53):c.700T>C (p.Tyr234His) rs864622237
NM_000546.5(TP53):c.706T>C (p.Tyr236His) rs587782289
NM_000546.5(TP53):c.706T>G (p.Tyr236Asp) rs587782289
NM_000546.5(TP53):c.711_712GT[1] (p.Met237_Cys238insTer) rs1555525539
NM_000546.5(TP53):c.712T>A (p.Cys238Ser) rs1057519981
NM_000546.5(TP53):c.712T>C (p.Cys238Arg) rs1057519981
NM_000546.5(TP53):c.713G>A (p.Cys238Tyr) rs730882005
NM_000546.5(TP53):c.714del (p.Met237_Cys238insTer) rs1555525537
NM_000546.5(TP53):c.725G>A (p.Cys242Tyr) rs121912655
NM_000546.5(TP53):c.730_744del (p.Gly244_Arg248del) rs1555525486
NM_000546.5(TP53):c.733G>A (p.Gly245Ser) rs28934575
NM_000546.5(TP53):c.733G>T (p.Gly245Cys) rs28934575
NM_000546.5(TP53):c.734G>A (p.Gly245Asp) rs121912656
NM_000546.5(TP53):c.736A>G (p.Met246Val) rs483352695
NM_000546.5(TP53):c.742C>T (p.Arg248Trp) rs121912651
NM_000546.5(TP53):c.743G>A (p.Arg248Gln) rs11540652
NM_000546.5(TP53):c.754del (p.Leu252fs) rs1555525470
NM_000546.5(TP53):c.766_770delACACTins16 (p.?)
NM_000546.5(TP53):c.766_770delinsCAGGTCAGGACATCCA (p.Thr256fs) rs876659098
NM_000546.5(TP53):c.772G>T (p.Glu258Ter) rs121912652
NM_000546.5(TP53):c.77_80delinsAAGAACGT (p.Leu26fs) rs397516438
NM_000546.5(TP53):c.783-1G>A rs1555525367
NM_000546.5(TP53):c.785del (p.Gly262fs) rs879253905
NM_000546.5(TP53):c.794T>C (p.Leu265Pro) rs879253942
NM_000546.5(TP53):c.795_796delinsCT (p.Gly266Ter) rs1555525344
NM_000546.5(TP53):c.796_808del (p.Gly266fs) rs886039855
NM_000546.5(TP53):c.797G>A (p.Gly266Glu) rs193920774
NM_000546.5(TP53):c.808_817del (p.Phe270fs) rs587781987
NM_000546.5(TP53):c.817C>A (p.Arg273Ser) rs121913343
NM_000546.5(TP53):c.817C>T (p.Arg273Cys) rs121913343
NM_000546.5(TP53):c.818G>A (p.Arg273His) rs28934576
NM_000546.5(TP53):c.818G>T (p.Arg273Leu) rs28934576
NM_000546.5(TP53):c.826G>C (p.Ala276Pro) rs1131691029
NM_000546.5(TP53):c.827C>G (p.Ala276Gly) rs786202082
NM_000546.5(TP53):c.833C>T (p.Pro278Leu) rs876659802
NM_000546.5(TP53):c.839del (p.Arg280fs) rs1567547721
NM_000546.5(TP53):c.842A>G (p.Asp281Gly) rs587781525
NM_000546.5(TP53):c.842_843insG (p.Asp281fs) rs1555525226
NM_000546.5(TP53):c.844C>G (p.Arg282Gly) rs28934574
NM_000546.5(TP53):c.844C>T (p.Arg282Trp) rs28934574
NM_000546.5(TP53):c.844del (p.Arg282fs) rs1131691027
NM_000546.5(TP53):c.856G>A (p.Glu286Lys) rs786201059
NM_000546.5(TP53):c.859_860GA[3] (p.Asn288fs) rs1555525158
NM_000546.5(TP53):c.863_864insGGCACAGAGGAAGAGAA (p.Asn288fs) rs1555525156
NM_000546.5(TP53):c.86_96+4del rs1555526916
NM_000546.5(TP53):c.892G>T (p.Glu298Ter) rs201744589
NM_000546.5(TP53):c.902del (p.Pro301fs) rs876660726
NM_000546.5(TP53):c.906del (p.Ser303fs) rs786202055
NM_000546.5(TP53):c.912dup (p.Lys305Ter) rs1567546818
NM_000546.5(TP53):c.916C>T (p.Arg306Ter) rs121913344
NM_000546.5(TP53):c.919+2T>G rs1131691016
NM_000546.5(TP53):c.920-1G>A rs587781702
NM_000546.5(TP53):c.920-1G>T rs587781702
NM_000546.5(TP53):c.949C>T (p.Gln317Ter) rs764735889
NM_000546.5(TP53):c.950del (p.Gln317fs) rs1555524976
NM_000546.5(TP53):c.96+1G>C rs1131691003
NM_000546.5(TP53):c.968_986del (p.Leu323fs) rs1567545918
NM_000546.5(TP53):c.976G>T (p.Glu326Ter) rs876659384
NM_000546.5(TP53):c.97dup (p.Ser33fs) rs1131691041
NM_000546.5(TP53):c.993+1del rs1131691033
NM_000546.5(TP53):c.994-1G>A rs587782272
NM_000546.5(TP53):c.994-1G>C rs587782272

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