ClinVar Miner

List of variants in gene TP53 reported as likely benign for TP53-related disorder

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Gene type:
ClinVar version:
Total variants: 54
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HGVS dbSNP gnomAD frequency
NM_000546.6(TP53):c.*1175A>C rs78378222 0.00849
NM_000546.5(TP53):c.319T>C (p.Tyr107His) rs368771578 0.00027
NM_000546.6(TP53):c.173C>G (p.Pro58Arg) rs144386518 0.00027
NM_000546.6(TP53):c.704A>G (p.Asn235Ser) rs144340710 0.00025
NM_000546.6(TP53):c.560-8G>C rs373797299 0.00018
NM_000546.6(TP53):c.935C>G (p.Thr312Ser) rs145151284 0.00018
NM_000546.6(TP53):c.869G>A (p.Arg290His) rs55819519 0.00014
NM_000546.6(TP53):c.993+223T>G rs3021068 0.00011
NM_000546.6(TP53):c.6G>A (p.Glu2=) rs143458271 0.00009
NM_000546.6(TP53):c.91G>A (p.Val31Ile) rs201753350 0.00009
NM_000546.6(TP53):c.248C>T (p.Ala83Val) rs201717599 0.00007
NM_000546.6(TP53):c.618G>A (p.Leu206=) rs142813240 0.00007
NM_000546.6(TP53):c.993+228A>G rs761121529 0.00007
NM_000546.6(TP53):c.993+310G>A rs201293647 0.00007
NC_000017.11:g.7668194C>T rs1056550417 0.00006
NM_000546.6(TP53):c.1015G>A (p.Glu339Lys) rs17882252 0.00006
NM_000546.6(TP53):c.97-28T>A rs200989844 0.00006
NM_000546.6(TP53):c.1096T>G (p.Ser366Ala) rs17881470 0.00005
NM_000546.6(TP53):c.993+234G>A rs17883348 0.00005
NM_000546.6(TP53):c.255T>C (p.Pro85=) rs775515332 0.00004
NM_000546.6(TP53):c.28G>A (p.Val10Ile) rs535274413 0.00004
NM_000546.6(TP53):c.450A>G (p.Thr150=) rs754020850 0.00004
NM_000546.6(TP53):c.612G>A (p.Glu204=) rs749629973 0.00004
NM_000546.6(TP53):c.993+312C>T rs756952434 0.00004
NM_000546.6(TP53):c.993+313G>A rs372821099 0.00004
NM_000546.6(TP53):c.*1169A>G rs918073756 0.00003
NM_000546.6(TP53):c.1120G>C (p.Gly374Arg) rs587781858 0.00003
NM_000546.6(TP53):c.509C>T (p.Thr170Met) rs779000871 0.00003
NM_000546.6(TP53):c.1066G>C (p.Gly356Arg) rs766786605 0.00001
NM_000546.6(TP53):c.1093C>T (p.His365Tyr) rs267605075 0.00001
NM_000546.6(TP53):c.245C>T (p.Pro82Leu) rs534447939 0.00001
NM_000546.6(TP53):c.270C>T (p.Ser90=) rs863224370 0.00001
NM_000546.6(TP53):c.354A>T (p.Thr118=) rs751978853 0.00001
NM_000546.6(TP53):c.390C>T (p.Leu130=) rs781537596 0.00001
NM_000546.6(TP53):c.54A>G (p.Thr18=) rs876659984 0.00001
NM_000546.6(TP53):c.66A>G (p.Leu22=) rs748527030 0.00001
NM_000546.6(TP53):c.673-45C>T rs1209285932 0.00001
NM_000546.6(TP53):c.673-9del rs762540407 0.00001
NM_000546.6(TP53):c.885T>C (p.Pro295=) rs200073907 0.00001
NM_000546.6(TP53):c.891C>T (p.His297=) rs750578863 0.00001
NM_000546.6(TP53):c.919+7A>C rs199527475 0.00001
NM_000546.6(TP53):c.943T>A (p.Ser315Thr) rs762620193 0.00001
NM_000546.6(TP53):c.949C>A (p.Gln317Lys) rs764735889 0.00001
NM_000546.6(TP53):c.993+213A>G rs912136376 0.00001
NM_000546.6(TP53):c.993+307C>G rs200274944 0.00001
NM_000546.6(TP53):c.993+314dup rs1567545210 0.00001
NC_000017.11:g.7668195G>A rs781520227
NM_000546.6(TP53):c.18A>G (p.Ser6=) rs573130482
NM_000546.6(TP53):c.215C>A (p.Pro72His) rs1042522
NM_000546.6(TP53):c.31G>C (p.Glu11Gln) rs201382018
NM_000546.6(TP53):c.567C>T (p.Ala189=) rs55764374
NM_000546.6(TP53):c.666G>T (p.Pro222=) rs72661118
NM_000546.6(TP53):c.673-29C>G
NM_000546.6(TP53):c.843C>T (p.Asp281=) rs1057519984

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