ClinVar Miner

List of variants in gene TP53 reported by German Consortium for Hereditary Breast and Ovarian Cancer Center Cologne,University Hospital Cologne

Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:
Total variants: 224
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HGVS dbSNP
NM_000546.5(TP53):c.1009C>T (p.Arg337Cys) rs587782529
NM_000546.5(TP53):c.1010G>T (p.Arg337Leu) rs121912664
NM_000546.5(TP53):c.1014_1015insT (p.Glu339Ter) rs1567542146
NM_000546.5(TP53):c.1024C>T (p.Arg342Ter) rs730882029
NM_000546.5(TP53):c.1024del (p.Arg342fs) rs1131691022
NM_000546.5(TP53):c.1025G>C (p.Arg342Pro) rs375338359
NM_000546.5(TP53):c.1027_1034del (p.Arg342_Glu343insTer) rs1567542043
NM_000546.5(TP53):c.1036G>T (p.Glu346Ter) rs1567542019
NM_000546.5(TP53):c.1036del (p.Glu346fs) rs1567542031
NM_000546.5(TP53):c.1045G>T (p.Glu349Ter) rs1567541975
NM_000546.5(TP53):c.153dup (p.Gln52fs) rs1567556914
NM_000546.5(TP53):c.155_158dup (p.Trp53Ter) rs1195793509
NM_000546.5(TP53):c.158G>A (p.Trp53Ter) rs876658483
NM_000546.5(TP53):c.176del (p.Gly59fs) rs1567556784
NM_000546.5(TP53):c.193A>T (p.Arg65Ter) rs1555526721
NM_000546.5(TP53):c.216del (p.Val73fs) rs730882018
NM_000546.5(TP53):c.224dup (p.Ala76fs) rs1567556454
NM_000546.5(TP53):c.246_253del (p.Ala83fs) rs1567556270
NM_000546.5(TP53):c.247del (p.Ala83fs) rs867725248
NM_000546.5(TP53):c.260_270del (p.Pro87fs) rs1567556165
NM_000546.5(TP53):c.267dup (p.Ser90fs) rs587783062
NM_000546.5(TP53):c.273G>A (p.Trp91Ter) rs876660548
NM_000546.5(TP53):c.277del (p.Leu93fs) rs1567556123
NM_000546.5(TP53):c.278del (p.Leu93fs) rs1567556114
NM_000546.5(TP53):c.284_288del (p.Ser95fs) rs878854068
NM_000546.5(TP53):c.298C>T (p.Gln100Ter) rs1567555994
NM_000546.5(TP53):c.298del (p.Gln100fs) rs1567556006
NM_000546.5(TP53):c.310C>T (p.Gln104Ter) rs1567555934
NM_000546.5(TP53):c.310del (p.Gln104fs) rs1567555939
NM_000546.5(TP53):c.314G>T (p.Gly105Val) rs587781504
NM_000546.5(TP53):c.326T>G (p.Phe109Cys) rs1064796722
NM_000546.5(TP53):c.329G>T (p.Arg110Leu) rs11540654
NM_000546.5(TP53):c.332T>C (p.Leu111Pro) rs1057519997
NM_000546.5(TP53):c.338T>G (p.Phe113Cys) rs1567555667
NM_000546.5(TP53):c.341T>A (p.Leu114Ter) rs781724995
NM_000546.5(TP53):c.358A>G (p.Lys120Glu) rs121912658
NM_000546.5(TP53):c.361_371del (p.Ser121fs) rs1567555504
NM_000546.5(TP53):c.363_364TG[1] (p.Val122fs) rs587780067
NM_000546.5(TP53):c.371dup (p.Cys124fs) rs1267047192
NM_000546.5(TP53):c.375+1G>A rs1567555445
NM_000546.5(TP53):c.375+5G>A rs1555526466
NM_000546.5(TP53):c.375+5G>T rs1555526466
NM_000546.5(TP53):c.376-1G>A rs868137297
NM_000546.5(TP53):c.376-2A>G rs786202799
NM_000546.5(TP53):c.376-2A>T rs786202799
NM_000546.5(TP53):c.376T>G (p.Tyr126Asp) rs886039483
NM_000546.5(TP53):c.376del (p.Tyr126fs) rs1567554542
NM_000546.5(TP53):c.377A>G (p.Tyr126Cys) rs1555526335
NM_000546.5(TP53):c.380C>T (p.Ser127Phe) rs730881999
NM_000546.5(TP53):c.393del (p.Asn131fs) rs1567554408
NM_000546.5(TP53):c.395A>G (p.Lys132Arg) rs1057519996
NM_000546.5(TP53):c.396G>T (p.Lys132Asn) rs866775781
NM_000546.5(TP53):c.403T>G (p.Cys135Gly) rs1057519975
NM_000546.5(TP53):c.415A>T (p.Lys139Ter) rs1212996409
NM_000546.5(TP53):c.422G>A (p.Cys141Tyr) rs587781288
NM_000546.5(TP53):c.430C>T (p.Gln144Ter) rs757274881
NM_000546.5(TP53):c.431A>C (p.Gln144Pro) rs786203071
NM_000546.5(TP53):c.434T>A (p.Leu145Gln) rs587782197
NM_000546.5(TP53):c.434T>C (p.Leu145Pro) rs587782197
NM_000546.5(TP53):c.437G>A (p.Trp146Ter) rs1206165503
NM_000546.5(TP53):c.439del (p.Val147fs) rs1567553924
NM_000546.5(TP53):c.443_460dup (p.Asp148_Pro153dup) rs1567553717
NM_000546.5(TP53):c.445del (p.Ser149fs) rs1064793929
NM_000546.5(TP53):c.445dup (p.Ser149fs) rs1064793929
NM_000546.5(TP53):c.450_452delinsT (p.Pro152fs) rs1567553834
NM_000546.5(TP53):c.451C>T (p.Pro151Ser) rs28934874
NM_000546.5(TP53):c.452C>A (p.Pro151His) rs1057520000
NM_000546.5(TP53):c.454_466del (p.Pro152fs) rs876659215
NM_000546.5(TP53):c.455del (p.Pro152fs) rs730882019
NM_000546.5(TP53):c.458_466del (p.Pro153_Thr155del) rs1567553613
NM_000546.5(TP53):c.460_463del (p.Gly154fs) rs1567553658
NM_000546.5(TP53):c.467G>C (p.Arg156Pro) rs371524413
NM_000546.5(TP53):c.469G>T (p.Val157Phe) rs121912654
NM_000546.5(TP53):c.471_474del (p.Arg158fs) rs1567553514
NM_000546.5(TP53):c.475G>C (p.Ala159Pro) rs730882000
NM_000546.5(TP53):c.481G>A (p.Ala161Thr) rs193920817
NM_000546.5(TP53):c.488A>G (p.Tyr163Cys) rs148924904
NM_000546.5(TP53):c.493C>T (p.Gln165Ter) rs730882001
NM_000546.5(TP53):c.497C>G (p.Ser166Ter) rs1555526101
NM_000546.5(TP53):c.511G>T (p.Glu171Ter) rs587781845
NM_000546.5(TP53):c.517G>A (p.Val173Met) rs876660754
NM_000546.5(TP53):c.517G>T (p.Val173Leu) rs876660754
NM_000546.5(TP53):c.523C>G (p.Arg175Gly) rs138729528
NM_000546.5(TP53):c.523C>T (p.Arg175Cys) rs138729528
NM_000546.5(TP53):c.524G>A (p.Arg175His) rs28934578
NM_000546.5(TP53):c.526T>C (p.Cys176Arg) rs967461896
NM_000546.5(TP53):c.526T>G (p.Cys176Gly) rs967461896
NM_000546.5(TP53):c.526_528delinsCGG (p.Cys176Arg) rs1567552847
NM_000546.5(TP53):c.528C>G (p.Cys176Trp) rs1057519980
NM_000546.5(TP53):c.532del (p.His178fs) rs786202525
NM_000546.5(TP53):c.533_540del (p.His178fs) rs1567552637
NM_000546.5(TP53):c.535C>T (p.His179Tyr) rs587780070
NM_000546.5(TP53):c.536A>G (p.His179Arg) rs1057519991
NM_000546.5(TP53):c.538G>T (p.Glu180Ter) rs879253911
NM_000546.5(TP53):c.545del (p.Cys182fs) rs1567552584
NM_000546.5(TP53):c.548C>G (p.Ser183Ter) rs1555525970
NM_000546.5(TP53):c.551del (p.Asp184fs) rs1567552536
NM_000546.5(TP53):c.560-1G>A rs1202793339
NM_000546.5(TP53):c.560-1G>C rs1202793339
NM_000546.5(TP53):c.560-3T>G rs763746485
NM_000546.5(TP53):c.578A>G (p.His193Arg) rs786201838
NM_000546.5(TP53):c.578A>T (p.His193Leu) rs786201838
NM_000546.5(TP53):c.581T>A (p.Leu194His) rs1057519998
NM_000546.5(TP53):c.581T>G (p.Leu194Arg) rs1057519998
NM_000546.5(TP53):c.582del (p.Ile195fs) rs1567552031
NM_000546.5(TP53):c.584T>A (p.Ile195Asn) rs760043106
NM_000546.5(TP53):c.584T>C (p.Ile195Thr) rs760043106
NM_000546.5(TP53):c.586C>T (p.Arg196Ter) rs397516435
NM_000546.5(TP53):c.590T>A (p.Val197Glu) rs1567551903
NM_000546.5(TP53):c.592G>T (p.Glu198Ter) rs1567551854
NM_000546.5(TP53):c.595G>T (p.Gly199Ter) rs1567551821
NM_000546.5(TP53):c.609_610delinsCT (p.Glu204Ter) rs1567551718
NM_000546.5(TP53):c.626_627del (p.Arg209fs) rs1057517840
NM_000546.5(TP53):c.635_636del (p.Phe212fs) rs864309495
NM_000546.5(TP53):c.637C>T (p.Arg213Ter) rs397516436
NM_000546.5(TP53):c.643A>G (p.Ser215Gly) rs886039484
NM_000546.5(TP53):c.643dup (p.Ser215fs) rs1567551402
NM_000546.5(TP53):c.644G>T (p.Ser215Ile) rs587782177
NM_000546.5(TP53):c.645T>G (p.Ser215Arg) rs1057520001
NM_000546.5(TP53):c.646G>A (p.Val216Met) rs730882025
NM_000546.5(TP53):c.646G>T (p.Val216Leu) rs730882025
NM_000546.5(TP53):c.646_648GTG[2] (p.Val218del)
NM_000546.5(TP53):c.647_651dup (p.Val218fs) rs1567551279
NM_000546.5(TP53):c.658T>C (p.Tyr220His) rs530941076
NM_000546.5(TP53):c.659A>C (p.Tyr220Ser) rs121912666
NM_000546.5(TP53):c.659A>G (p.Tyr220Cys) rs121912666
NM_000546.5(TP53):c.660T>A (p.Tyr220Ter) rs1567551150
NM_000546.5(TP53):c.661G>T (p.Glu221Ter) rs786201592
NM_000546.5(TP53):c.665del (p.Pro222fs) rs1567551073
NM_000546.5(TP53):c.672+1G>T rs863224499
NM_000546.5(TP53):c.672del rs1567550969
NM_000546.5(TP53):c.673-2A>G rs1555525585
NM_000546.5(TP53):c.675del (p.Gly226fs) rs1567550076
NM_000546.5(TP53):c.680del (p.Ser227fs) rs1567550018
NM_000546.5(TP53):c.681dup (p.Asp228Ter) rs1567550002
NM_000546.5(TP53):c.695T>G (p.Ile232Ser) rs587781589
NM_000546.5(TP53):c.700T>C (p.Tyr234His) rs864622237
NM_000546.5(TP53):c.701A>G (p.Tyr234Cys) rs587780073
NM_000546.5(TP53):c.707A>G (p.Tyr236Cys) rs730882026
NM_000546.5(TP53):c.711G>A (p.Met237Ile) rs587782664
NM_000546.5(TP53):c.711G>T (p.Met237Ile) rs587782664
NM_000546.5(TP53):c.712T>G (p.Cys238Gly) rs1057519981
NM_000546.5(TP53):c.712_738del (p.Cys238_Met246del) rs1567549353
NM_000546.5(TP53):c.713G>A (p.Cys238Tyr) rs730882005
NM_000546.5(TP53):c.714dup (p.Asn239Ter) rs1567549651
NM_000546.5(TP53):c.721T>C (p.Ser241Pro) rs1057520002
NM_000546.5(TP53):c.722C>A (p.Ser241Tyr) rs28934573
NM_000546.5(TP53):c.722C>G (p.Ser241Cys) rs28934573
NM_000546.5(TP53):c.722C>T (p.Ser241Phe) rs28934573
NM_000546.5(TP53):c.725G>A (p.Cys242Tyr) rs121912655
NM_000546.5(TP53):c.725G>T (p.Cys242Phe) rs121912655
NM_000546.5(TP53):c.727_782+21dup rs1567548789
NM_000546.5(TP53):c.731G>A (p.Gly244Asp) rs985033810
NM_000546.5(TP53):c.731G>T (p.Gly244Val) rs985033810
NM_000546.5(TP53):c.733G>A (p.Gly245Ser) rs28934575
NM_000546.5(TP53):c.734G>A (p.Gly245Asp) rs121912656
NM_000546.5(TP53):c.736A>G (p.Met246Val) rs483352695
NM_000546.5(TP53):c.737T>C (p.Met246Thr) rs587780074
NM_000546.5(TP53):c.740A>T (p.Asn247Ile) rs786201762
NM_000546.5(TP53):c.742C>T (p.Arg248Trp) rs121912651
NM_000546.5(TP53):c.743G>A (p.Arg248Gln) rs11540652
NM_000546.5(TP53):c.745A>G (p.Arg249Gly) rs587782082
NM_000546.5(TP53):c.746G>T (p.Arg249Met) rs587782329
NM_000546.5(TP53):c.747G>T (p.Arg249Ser) rs28934571
NM_000546.5(TP53):c.750del (p.Ile251fs) rs1567549203
NM_000546.5(TP53):c.751A>C (p.Ile251Leu) rs730882007
NM_000546.5(TP53):c.759del (p.Ile254fs) rs1567549129
NM_000546.5(TP53):c.763A>T (p.Ile255Phe) rs1057519995
NM_000546.5(TP53):c.770T>A (p.Leu257Gln) rs28934577
NM_000546.5(TP53):c.772G>A (p.Glu258Lys) rs121912652
NM_000546.5(TP53):c.772G>T (p.Glu258Ter) rs121912652
NM_000546.5(TP53):c.775G>T (p.Asp259Tyr) rs1567548929
NM_000546.5(TP53):c.782+1G>A rs1555525429
NM_000546.5(TP53):c.782+1G>T rs1555525429
NM_000546.5(TP53):c.783-1G>T rs1555525367
NM_000546.5(TP53):c.796G>A (p.Gly266Arg) rs1057519990
NM_000546.5(TP53):c.797G>A (p.Gly266Glu) rs193920774
NM_000546.5(TP53):c.797del (p.Gly266fs) rs1567548223
NM_000546.5(TP53):c.808T>A (p.Phe270Ile) rs1057519988
NM_000546.5(TP53):c.808T>C (p.Phe270Leu) rs1057519988
NM_000546.5(TP53):c.810del (p.Phe270fs) rs1567548114
NM_000546.5(TP53):c.814G>A (p.Val272Met) rs121912657
NM_000546.5(TP53):c.817C>G (p.Arg273Gly) rs121913343
NM_000546.5(TP53):c.817C>T (p.Arg273Cys) rs121913343
NM_000546.5(TP53):c.818G>A (p.Arg273His) rs28934576
NM_000546.5(TP53):c.818G>C (p.Arg273Pro) rs28934576
NM_000546.5(TP53):c.818G>T (p.Arg273Leu) rs28934576
NM_000546.5(TP53):c.824G>A (p.Cys275Tyr) rs863224451
NM_000546.5(TP53):c.824G>T (p.Cys275Phe) rs863224451
NM_000546.5(TP53):c.825T>G (p.Cys275Trp) rs1555525279
NM_000546.5(TP53):c.826G>C (p.Ala276Pro) rs1131691029
NM_000546.5(TP53):c.832C>A (p.Pro278Thr) rs17849781
NM_000546.5(TP53):c.832C>G (p.Pro278Ala) rs17849781
NM_000546.5(TP53):c.832C>T (p.Pro278Ser) rs17849781
NM_000546.5(TP53):c.833C>G (p.Pro278Arg) rs876659802
NM_000546.5(TP53):c.833C>T (p.Pro278Leu) rs876659802
NM_000546.5(TP53):c.836G>A (p.Gly279Glu) rs1064793881
NM_000546.5(TP53):c.838A>G (p.Arg280Gly) rs753660142
NM_000546.5(TP53):c.840A>C (p.Arg280Ser) rs1567547687
NM_000546.5(TP53):c.841G>A (p.Asp281Asn) rs764146326
NM_000546.5(TP53):c.843C>A (p.Asp281Glu) rs1057519984
NM_000546.5(TP53):c.843C>G (p.Asp281Glu) rs1057519984
NM_000546.5(TP53):c.844C>G (p.Arg282Gly) rs28934574
NM_000546.5(TP53):c.844C>T (p.Arg282Trp) rs28934574
NM_000546.5(TP53):c.845_889del (p.Arg282_His296del) rs1567547066
NM_000546.5(TP53):c.856G>T (p.Glu286Ter) rs786201059
NM_000546.5(TP53):c.888_892del (p.His296fs) rs1567547030
NM_000546.5(TP53):c.892G>T (p.Glu298Ter) rs201744589
NM_000546.5(TP53):c.908_909insGGGG (p.Ser303fs) rs1567546889
NM_000546.5(TP53):c.916C>T (p.Arg306Ter) rs121913344
NM_000546.5(TP53):c.919+1G>C rs1131691039
NM_000546.5(TP53):c.920-1G>A rs587781702
NM_000546.5(TP53):c.920-1G>T rs587781702
NM_000546.5(TP53):c.920-2A>G rs397516439
NM_000546.5(TP53):c.933del (p.Asn311fs) rs1567546373
NM_000546.5(TP53):c.937_946del (p.Ser313fs) rs1567546226
NM_000546.5(TP53):c.949del (p.Gln317fs) rs1567546196
NM_000546.5(TP53):c.97-2del rs1567557258
NM_000546.5(TP53):c.976G>T (p.Glu326Ter) rs876659384
NM_000546.5(TP53):c.978_979AT[1] (p.Tyr327fs)
NM_000546.5(TP53):c.993+1G>A rs11575997
NM_000546.5(TP53):c.993+1G>T rs11575997
NM_000546.5(TP53):c.994-22_1003del rs1567542245
NM_000546.5(TP53):c.996_997del (p.Ile332fs) rs1567542299

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