List of variants in gene TP53 reported as pathogenic by University Health Network, Princess Margaret Cancer Centre

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 17

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HGVS	dbSNP	gnomAD frequency
NM_000546.6(TP53):c.743G>A (p.Arg248Gln)	rs11540652	0.00002
NM_000546.6(TP53):c.375G>A (p.Thr125=)	rs55863639	0.00001
NM_000546.6(TP53):c.524G>A (p.Arg175His)	rs28934578	0.00001
NM_000546.6(TP53):c.542G>A (p.Arg181His)	rs397514495	0.00001
NM_000546.6(TP53):c.659A>G (p.Tyr220Cys)	rs121912666	0.00001
NM_000546.6(TP53):c.733G>A (p.Gly245Ser)	rs28934575	0.00001
NM_000546.6(TP53):c.-19_*21del (p.Met1fs)
NM_000546.6(TP53):c.1118del (p.Lys373fs)	rs2150988776
NM_000546.6(TP53):c.380C>T (p.Ser127Phe)	rs730881999
NM_000546.6(TP53):c.438G>A (p.Trp146Ter)	rs1131691026
NM_000546.6(TP53):c.537T>A (p.His179Gln)	rs876660821
NM_000546.6(TP53):c.586C>T (p.Arg196Ter)	rs397516435
NM_000546.6(TP53):c.637C>T (p.Arg213Ter)	rs397516436
NM_000546.6(TP53):c.742C>T (p.Arg248Trp)	rs121912651
NM_000546.6(TP53):c.811G>T (p.Glu271Ter)	rs1060501191
NM_000546.6(TP53):c.818G>A (p.Arg273His)	rs28934576
NM_000546.6(TP53):c.880G>T (p.Glu294Ter)	rs1057520607

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