ClinVar Miner

List of variants in gene TP53 reported as uncertain significance by Laboratory of Virology, Oncology, Biosciences and Environment, Faculty of Sciences and Techniques, Mohammedia- University Hassan II of Casablanca

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Gene type:
ClinVar version:
Total variants: 110
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HGVS dbSNP gnomAD frequency
NM_000546.6(TP53):c.376-13C>T rs2073407612 0.00001
NM_000546.6(TP53):c.376-4A>C rs1221388024 0.00001
NM_000546.6(TP53):c.376-11T>C rs747705704
NM_000546.6(TP53):c.376-11del rs2543609548
NM_000546.6(TP53):c.376-12del rs2543609619
NM_000546.6(TP53):c.376-12dup rs2543609619
NM_000546.6(TP53):c.376-2A>C rs786202799
NM_000546.6(TP53):c.376-2del rs2543609050
NM_000546.6(TP53):c.376-36dup rs2543610414
NM_000546.6(TP53):c.376-3del rs2543609119
NM_000546.6(TP53):c.376-3delinsAG rs2543609100
NM_000546.6(TP53):c.376-48T>A rs2151034793
NM_000546.6(TP53):c.376-4_376-3delinsTA rs2543609149
NM_000546.6(TP53):c.376-6C>G rs2151034268
NM_000546.6(TP53):c.376-6_376-5insG rs2543609253
NM_000546.6(TP53):c.376-6del rs2543609319
NM_000546.6(TP53):c.376-8del rs2543609426
NM_000546.6(TP53):c.376-8dup rs2543609426
NM_000546.6(TP53):c.376-9T>C rs2151034304
NM_000546.6(TP53):c.376_377delinsCT (p.Tyr126Leu) rs2543608733
NM_000546.6(TP53):c.376delinsAG (p.Tyr126fs) rs2543608878
NM_000546.6(TP53):c.376delinsGG (p.Tyr126fs) rs2543608878
NM_000546.6(TP53):c.377dup (p.Tyr126Ter) rs2543608702
NM_000546.6(TP53):c.378C>A (p.Tyr126Ter) rs1567554500
NM_000546.6(TP53):c.379dup (p.Ser127fs) rs2543608507
NM_000546.6(TP53):c.382C>T (p.Pro128Ser) rs1555526327
NM_000546.6(TP53):c.383del (p.Pro128fs) rs1597371666
NM_000546.6(TP53):c.383dup (p.Ala129fs) rs1597371666
NM_000546.6(TP53):c.386_387insA (p.Leu130fs) rs2543607861
NM_000546.6(TP53):c.387C>T (p.Ala129=) rs2543607814
NM_000546.6(TP53):c.388_390delinsGAT (p.Leu130Asp) rs2543607632
NM_000546.6(TP53):c.388del (p.Leu130fs) rs2151033977
NM_000546.6(TP53):c.388dup (p.Leu130fs) rs2151033977
NM_000546.6(TP53):c.390C>G (p.Leu130=) rs781537596
NM_000546.6(TP53):c.392del (p.Asn131fs) rs2543607530
NM_000546.6(TP53):c.393del (p.Asn131fs) rs1567554408
NM_000546.6(TP53):c.395del (p.Lys132fs) rs2543607141
NM_000546.6(TP53):c.396_397insT (p.Met133fs) rs2543607000
NM_000546.6(TP53):c.398T>G (p.Met133Arg) rs28934873
NM_000546.6(TP53):c.401_402delinsCTG (p.Phe134fs) rs2543606686
NM_000546.6(TP53):c.409dup (p.Leu137fs) rs2543606066
NM_000546.6(TP53):c.413C>G (p.Ala138Gly) rs750600586
NM_000546.6(TP53):c.413_414insG (p.Lys139fs) rs2543605636
NM_000546.6(TP53):c.413delinsTG (p.Ala138fs) rs2543605741
NM_000546.6(TP53):c.415_416delinsG (p.Lys139fs) rs1597371266
NM_000546.6(TP53):c.417_418insT (p.Thr140fs) rs2543605230
NM_000546.6(TP53):c.421del (p.Cys141fs) rs2543604994
NM_000546.6(TP53):c.421dup (p.Cys141fs) rs2543604967
NM_000546.6(TP53):c.422_423insT (p.Val143fs) rs2543604782
NM_000546.6(TP53):c.422dup (p.Cys141fs) rs2073394466
NM_000546.6(TP53):c.424_425del (p.Pro142fs) rs2151033162
NM_000546.6(TP53):c.427G>C (p.Val143Leu) rs587782620
NM_000546.6(TP53):c.427_428insC (p.Val143fs) rs2543604310
NM_000546.6(TP53):c.428T>A (p.Val143Glu) rs1555526241
NM_000546.6(TP53):c.428del (p.Val143fs) rs2543604251
NM_000546.6(TP53):c.428dup (p.Gln144fs) rs2543604218
NM_000546.6(TP53):c.431A>G (p.Gln144Arg) rs786203071
NM_000546.6(TP53):c.431del (p.Gln144fs) rs2543603860
NM_000546.6(TP53):c.432_433delinsCA (p.Gln144_Leu145delinsHisMet) rs2543603624
NM_000546.6(TP53):c.432del (p.Gln144fs) rs2543603783
NM_000546.6(TP53):c.433del (p.Leu145fs) rs2543603585
NM_000546.6(TP53):c.435_436delinsAAG (p.Trp146fs) rs2543603392
NM_000546.6(TP53):c.441T>G (p.Val147=) rs2151032835
NM_000546.6(TP53):c.443A>T (p.Asp148Val) rs1046611742
NM_000546.6(TP53):c.453C>A (p.Pro151=) rs2151032585
NM_000546.6(TP53):c.454C>A (p.Pro152Thr) rs767328513
NM_000546.6(TP53):c.457C>G (p.Pro153Ala) rs1064795860
NM_000546.6(TP53):c.457_458insATGTCGCCACGCGGTCCGAC (p.Pro153fs) rs2543601871
NM_000546.6(TP53):c.460_462delinsAT (p.Gly154fs) rs2543601249
NM_000546.6(TP53):c.461_462delinsAT (p.Gly154Asp) rs2543601170
NM_000546.6(TP53):c.461_462delinsCAT (p.Gly154fs) rs2543601211
NM_000546.6(TP53):c.461_463delinsCAT (p.Gly154_Thr155delinsAlaSer) rs2543601013
NM_000546.6(TP53):c.461delinsAT (p.Gly154fs) rs2543601339
NM_000546.6(TP53):c.463del (p.Thr155fs) rs2543600979
NM_000546.6(TP53):c.476C>A (p.Ala159Asp) rs1555526131
NM_000546.6(TP53):c.490A>C (p.Lys164Gln) rs879254249
NM_000546.6(TP53):c.491del (p.Lys164fs) rs2543598620
NM_000546.6(TP53):c.492_493delinsTT (p.Lys164_Gln165delinsAsnTer) rs1567553215
NM_000546.6(TP53):c.493delinsAA (p.Gln165fs) rs2468379264
NM_000546.6(TP53):c.495_499delinsCCCTA (p.Gln165_Gln167delinsHisProLys) rs2543597928
NM_000546.6(TP53):c.496T>G (p.Ser166Ala) rs2073374897
NM_000546.6(TP53):c.496_497insG (p.Ser166fs) rs2543598281
NM_000546.6(TP53):c.496_497insGC (p.Ser166fs) rs2543598281
NM_000546.6(TP53):c.498del (p.Gln167fs) rs2543598057
NM_000546.6(TP53):c.499_500del (p.Gln167fs) rs2543597805
NM_000546.6(TP53):c.502C>A (p.His168Asn) rs2543597642
NM_000546.6(TP53):c.503dup (p.His168fs) rs2543597561
NM_000546.6(TP53):c.511_512insC (p.Glu171fs) rs2543596825
NM_000546.6(TP53):c.516del (p.Val172_Val173insTer) rs2543596479
NM_000546.6(TP53):c.522del (p.Arg174fs) rs2543595963
NM_000546.6(TP53):c.522dup (p.Arg175fs) rs2543595963
NM_000546.6(TP53):c.531C>A (p.Pro177=) rs1597369785
NM_000546.6(TP53):c.531CCA[1] (p.His179del) rs2543594701
NM_000546.6(TP53):c.532dup (p.His178fs) rs786202525
NM_000546.6(TP53):c.533dup (p.His178fs) rs2543595042
NM_000546.6(TP53):c.539dup (p.Arg181fs) rs2543594381
NM_000546.6(TP53):c.545del (p.Cys182fs) rs1567552584
NM_000546.6(TP53):c.546del (p.Ser183fs) rs2543593744
NM_000546.6(TP53):c.548_549insT (p.Asp184fs) rs2543593506
NM_000546.6(TP53):c.548dup (p.Asp184fs) rs2543593604
NM_000546.6(TP53):c.550G>C (p.Asp184His) rs72661117
NM_000546.6(TP53):c.550_551insC (p.Asp184fs) rs2543593200
NM_000546.6(TP53):c.550del (p.Asp184fs) rs2543593367
NM_000546.6(TP53):c.550dup (p.Asp184fs) rs2543593328
NM_000546.6(TP53):c.554del (p.Ser185fs) rs2543592929
NM_000546.6(TP53):c.554dup (p.Ser185fs) rs2543592903
NM_000546.6(TP53):c.555dup (p.Asp186fs) rs2531712915
NM_000546.6(TP53):c.559+11G>T rs75343564
NM_000546.6(TP53):c.559+35G>A rs2151029195
NM_000546.6(TP53):c.559+5del rs2543592378

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