ClinVar Miner

List of variants in gene TSC2 reported as uncertain significance for Hereditary cancer-predisposing syndrome

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Gene type:
ClinVar version:
Total variants: 256
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HGVS dbSNP
NM_000548.4(TSC2):c.2640-4_2640-3delTC rs1555508570
NM_000548.5(TSC2):c.*4C>T rs368282661
NM_000548.5(TSC2):c.*5G>A rs201342697
NM_000548.5(TSC2):c.101A>G (p.Lys34Arg) rs777988634
NM_000548.5(TSC2):c.1066G>C (p.Val356Leu) rs587778728
NM_000548.5(TSC2):c.1096G>A (p.Glu366Lys) rs45517148
NM_000548.5(TSC2):c.1120-5T>C rs896351318
NM_000548.5(TSC2):c.1154A>G (p.His385Arg) rs757353933
NM_000548.5(TSC2):c.1187A>T (p.Asp396Val) rs1365616275
NM_000548.5(TSC2):c.119T>C (p.Ile40Thr) rs587781758
NM_000548.5(TSC2):c.1213G>C (p.Glu405Gln) rs765622787
NM_000548.5(TSC2):c.1244C>T (p.Ala415Val) rs374936223
NM_000548.5(TSC2):c.1260G>T (p.Glu420Asp) rs876658585
NM_000548.5(TSC2):c.1307C>T (p.Pro436Leu) rs796053485
NM_000548.5(TSC2):c.130A>G (p.Ile44Val) rs1555494697
NM_000548.5(TSC2):c.1317C>A (p.Asp439Glu) rs777457815
NM_000548.5(TSC2):c.1362-5C>T rs372424945
NM_000548.5(TSC2):c.1367A>G (p.Glu456Gly) rs876659386
NM_000548.5(TSC2):c.152A>C (p.Glu51Ala) rs772617064
NM_000548.5(TSC2):c.1565A>G (p.His522Arg) rs397515147
NM_000548.5(TSC2):c.1588A>G (p.Ile530Val) rs786203470
NM_000548.5(TSC2):c.1601T>G (p.Val534Gly) rs924098595
NM_000548.5(TSC2):c.1624C>A (p.Pro542Thr) rs891347695
NM_000548.5(TSC2):c.1654G>A (p.Ala552Thr) rs777121421
NM_000548.5(TSC2):c.1655C>T (p.Ala552Val) rs1555503231
NM_000548.5(TSC2):c.1675G>T (p.Asp559Tyr) rs1555503254
NM_000548.5(TSC2):c.1678G>A (p.Val560Met) rs141631268
NM_000548.5(TSC2):c.167A>G (p.Asn56Ser) rs144165984
NM_000548.5(TSC2):c.1721A>G (p.Lys574Arg) rs1060500926
NM_000548.5(TSC2):c.1735C>G (p.Pro579Ala) rs45517196
NM_000548.5(TSC2):c.1735C>T (p.Pro579Ser) rs45517196
NM_000548.5(TSC2):c.1754G>A (p.Arg585His) rs397515063
NM_000548.5(TSC2):c.176G>A (p.Arg59Gln) rs1161261925
NM_000548.5(TSC2):c.1774A>G (p.Ser592Gly) rs910068556
NM_000548.5(TSC2):c.17G>A (p.Ser6Asn) rs758239066
NM_000548.5(TSC2):c.1807A>T (p.Thr603Ser) rs876660140
NM_000548.5(TSC2):c.1816A>G (p.Ile606Val) rs371074761
NM_000548.5(TSC2):c.1820C>T (p.Ala607Val) rs397515296
NM_000548.5(TSC2):c.1828A>G (p.Ile610Val) rs1285778253
NM_000548.5(TSC2):c.1883G>A (p.Arg628His) rs774895427
NM_000548.5(TSC2):c.1903G>A (p.Asp635Asn) rs1060500932
NM_000548.5(TSC2):c.1915C>T (p.Arg639Trp) rs766451267
NM_000548.5(TSC2):c.1916G>A (p.Arg639Gln) rs753932484
NM_000548.5(TSC2):c.1937G>A (p.Cys646Tyr) rs1555505863
NM_000548.5(TSC2):c.1945A>G (p.Met649Val) rs762331610
NM_000548.5(TSC2):c.1946+4C>T rs752017577
NM_000548.5(TSC2):c.1946+5G>T rs766646261
NM_000548.5(TSC2):c.1947G>A (p.Met649Ile) rs775845436
NM_000548.5(TSC2):c.1958G>A (p.Arg653Lys) rs876658202
NM_000548.5(TSC2):c.1960G>A (p.Gly654Ser) rs397515114
NM_000548.5(TSC2):c.1981G>A (p.Gly661Ser) rs137854168
NM_000548.5(TSC2):c.1982_1983delinsTT (p.Gly661Val) rs137854103
NM_000548.5(TSC2):c.1990T>G (p.Ser664Ala) rs1555506028
NM_000548.5(TSC2):c.2018C>T (p.Ala673Val) rs745897413
NM_000548.5(TSC2):c.2023_2024delinsTT (p.Ala675Leu) rs1555506090
NM_000548.5(TSC2):c.2027G>T (p.Gly676Val) rs754556513
NM_000548.5(TSC2):c.2035G>A (p.Val679Met) rs746315218
NM_000548.5(TSC2):c.2038C>T (p.Arg680Trp) rs876658578
NM_000548.5(TSC2):c.2050G>A (p.Val684Met) rs779275341
NM_000548.5(TSC2):c.2071C>T (p.Arg691Cys) rs760489473
NM_000548.5(TSC2):c.2098-3C>T rs876660489
NM_000548.5(TSC2):c.2098-5C>G rs369072310
NM_000548.5(TSC2):c.2098-5C>T rs369072310
NM_000548.5(TSC2):c.20A>G (p.Lys7Arg) rs137854215
NM_000548.5(TSC2):c.2123T>C (p.Leu708Pro) rs876659689
NM_000548.5(TSC2):c.2153G>A (p.Arg718His) rs45517215
NM_000548.5(TSC2):c.2167A>G (p.Ile723Val) rs764725850
NM_000548.5(TSC2):c.2180C>T (p.Pro727Leu) rs767086409
NM_000548.5(TSC2):c.2220+4C>G rs781186613
NM_000548.5(TSC2):c.2221-5A>G rs1555506829
NM_000548.5(TSC2):c.2237C>T (p.Thr746Ile) rs767770242
NM_000548.5(TSC2):c.2239C>A (p.Leu747Met) rs45517221
NM_000548.5(TSC2):c.223G>A (p.Glu75Lys) rs145470784
NM_000548.5(TSC2):c.2246G>A (p.Arg749Gln) rs766442736
NM_000548.5(TSC2):c.2255G>A (p.Gly752Asp) rs876660553
NM_000548.5(TSC2):c.226C>T (p.His76Tyr) rs574779350
NM_000548.5(TSC2):c.2290C>G (p.Leu764Val) rs777614710
NM_000548.5(TSC2):c.2294C>T (p.Ala765Val) rs886042145
NM_000548.5(TSC2):c.2315C>T (p.Ala772Val) rs397514984
NM_000548.5(TSC2):c.2332A>G (p.Asn778Asp) rs1060500946
NM_000548.5(TSC2):c.2348C>T (p.Thr783Ile) rs562945619
NM_000548.5(TSC2):c.2356-4G>A rs201156748
NM_000548.5(TSC2):c.2365G>A (p.Val789Ile) rs779472379
NM_000548.5(TSC2):c.2465C>T (p.Ala822Val) rs936484229
NM_000548.5(TSC2):c.2515A>G (p.Met839Val) rs876660457
NM_000548.5(TSC2):c.2546-4G>A rs746958032
NM_000548.5(TSC2):c.2584G>A (p.Ala862Thr) rs759837836
NM_000548.5(TSC2):c.2621C>T (p.Pro874Leu) rs138527121
NM_000548.5(TSC2):c.2632C>T (p.Pro878Ser) rs397515077
NM_000548.5(TSC2):c.2640-5C>T rs753781434
NM_000548.5(TSC2):c.2712C>G (p.Phe904Leu) rs137920189
NM_000548.5(TSC2):c.2750G>A (p.Arg917Gln) rs397515046
NM_000548.5(TSC2):c.2780C>T (p.Thr927Ile) rs144329595
NM_000548.5(TSC2):c.2785G>A (p.Glu929Lys) rs45517268
NM_000548.5(TSC2):c.278G>A (p.Arg93Gln) rs1222477746
NM_000548.5(TSC2):c.2837+4C>T rs544409858
NM_000548.5(TSC2):c.2837+5G>A rs786203791
NM_000548.5(TSC2):c.2838-5G>A rs876660419
NM_000548.5(TSC2):c.2854C>A (p.Pro952Thr) rs745456980
NM_000548.5(TSC2):c.2866G>A (p.Gly956Ser) rs769199118
NM_000548.5(TSC2):c.292C>T (p.Arg98Trp) rs372321790
NM_000548.5(TSC2):c.2932C>T (p.Arg978Cys) rs768241596
NM_000548.5(TSC2):c.2933G>A (p.Arg978His) rs876660733
NM_000548.5(TSC2):c.2966+5C>T rs767328300
NM_000548.5(TSC2):c.2978C>T (p.Thr993Met) rs137854410
NM_000548.5(TSC2):c.2986A>G (p.Thr996Ala) rs139753238
NM_000548.5(TSC2):c.299C>T (p.Ala100Val) rs375824753
NM_000548.5(TSC2):c.3002G>A (p.Gly1001Glu) rs368878445
NM_000548.5(TSC2):c.301G>A (p.Val101Met) rs878854089
NM_000548.5(TSC2):c.3037G>A (p.Asp1013Asn) rs45517279
NM_000548.5(TSC2):c.3056A>C (p.His1019Pro) rs1555510317
NM_000548.5(TSC2):c.3100G>A (p.Val1034Ile) rs146745242
NM_000548.5(TSC2):c.3145G>A (p.Glu1049Lys) rs796053492
NM_000548.5(TSC2):c.3209C>T (p.Thr1070Met) rs147989574
NM_000548.5(TSC2):c.3212C>T (p.Thr1071Ile) rs45498892
NM_000548.5(TSC2):c.3232C>T (p.Arg1078Trp) rs78956195
NM_000548.5(TSC2):c.3254C>T (p.Ser1085Leu) rs45517287
NM_000548.5(TSC2):c.3257_3259del (p.Gly1086del) rs137854302
NM_000548.5(TSC2):c.3281C>G (p.Ser1094Trp) rs397514887
NM_000548.5(TSC2):c.3287C>T (p.Ser1096Phe) rs140772300
NM_000548.5(TSC2):c.3293C>T (p.Pro1098Leu) rs773545852
NM_000548.5(TSC2):c.3317A>T (p.Lys1106Met) rs764113584
NM_000548.5(TSC2):c.3323C>T (p.Ala1108Val) rs587781782
NM_000548.5(TSC2):c.3326C>T (p.Pro1109Leu) rs796053474
NM_000548.5(TSC2):c.3358G>C (p.Val1120Leu) rs1053311636
NM_000548.5(TSC2):c.3364C>T (p.Arg1122Cys) rs397514938
NM_000548.5(TSC2):c.3395C>T (p.Ser1132Leu) rs137854074
NM_000548.5(TSC2):c.3413G>C (p.Arg1138Pro) rs143168379
NM_000548.5(TSC2):c.3421_3453del (p.Ala1141_Gly1151del) rs1114167467
NM_000548.5(TSC2):c.3434C>T (p.Pro1145Leu) rs397515162
NM_000548.5(TSC2):c.3447C>A (p.Phe1149Leu) rs1265832990
NM_000548.5(TSC2):c.3469G>A (p.Gly1157Arg) rs1555511390
NM_000548.5(TSC2):c.3491C>T (p.Ala1164Val) rs45448801
NM_000548.5(TSC2):c.3527C>T (p.Pro1176Leu) rs753110463
NM_000548.5(TSC2):c.3535G>A (p.Glu1179Lys) rs45483391
NM_000548.5(TSC2):c.3540G>T (p.Lys1180Asn) rs1555511520
NM_000548.5(TSC2):c.3551C>T (p.Ala1184Val) rs1060500939
NM_000548.5(TSC2):c.3557A>G (p.Tyr1186Cys) rs137854421
NM_000548.5(TSC2):c.3584C>T (p.Ala1195Val) rs773951533
NM_000548.5(TSC2):c.3611-5C>T rs200194551
NM_000548.5(TSC2):c.362C>G (p.Ala121Gly) rs767755750
NM_000548.5(TSC2):c.3679C>T (p.Pro1227Ser) rs1555512392
NM_000548.5(TSC2):c.3698A>G (p.Asn1233Ser) rs1412376534
NM_000548.5(TSC2):c.375G>C (p.Lys125Asn) rs778928295
NM_000548.5(TSC2):c.3791_3793CTC[1] (p.Pro1265del) rs876658759
NM_000548.5(TSC2):c.3793C>T (p.Pro1265Ser) rs45517311
NM_000548.5(TSC2):c.37G>A (p.Glu13Lys) rs1555494586
NM_000548.5(TSC2):c.3802C>T (p.Arg1268Cys) rs1020561347
NM_000548.5(TSC2):c.3803G>A (p.Arg1268His) rs200577441
NM_000548.5(TSC2):c.3815-3C>T rs770054036
NM_000548.5(TSC2):c.3818C>T (p.Ala1273Val) rs749367382
NM_000548.5(TSC2):c.3871G>A (p.Val1291Ile) rs201135184
NM_000548.5(TSC2):c.3883+5C>T rs45448994
NM_000548.5(TSC2):c.3919G>A (p.Glu1307Lys) rs62642481
NM_000548.5(TSC2):c.3958G>A (p.Val1320Ile) rs767495365
NM_000548.5(TSC2):c.3968C>T (p.Ala1323Val) rs397515062
NM_000548.5(TSC2):c.3980A>G (p.Asp1327Gly) rs1555513553
NM_000548.5(TSC2):c.3981C>G (p.Asp1327Glu) rs876659087
NM_000548.5(TSC2):c.3989C>T (p.Thr1330Met) rs397515209
NM_000548.5(TSC2):c.4037C>T (p.Ser1346Leu) rs45517326
NM_000548.5(TSC2):c.4045G>A (p.Ala1349Thr) rs146239734
NM_000548.5(TSC2):c.4046C>T (p.Ala1349Val) rs201979616
NM_000548.5(TSC2):c.4057G>A (p.Val1353Ile) rs373982157
NM_000548.5(TSC2):c.4094C>T (p.Ser1365Leu) rs377123510
NM_000548.5(TSC2):c.4097A>C (p.Glu1366Ala) rs755461310
NM_000548.5(TSC2):c.4106G>A (p.Arg1369Gln) rs587778738
NM_000548.5(TSC2):c.4136C>T (p.Ser1379Leu) rs137854065
NM_000548.5(TSC2):c.4192C>G (p.Leu1398Val) rs1060500928
NM_000548.5(TSC2):c.4216G>T (p.Asp1406Tyr) rs147719291
NM_000548.5(TSC2):c.4219G>A (p.Val1407Met) rs45517332
NM_000548.5(TSC2):c.4223G>T (p.Gly1408Val) rs202068995
NM_000548.5(TSC2):c.4256A>G (p.Gln1419Arg) rs562443546
NM_000548.5(TSC2):c.4271A>G (p.Asp1424Gly) rs876659933
NM_000548.5(TSC2):c.4330C>G (p.Pro1444Ala) rs1459518095
NM_000548.5(TSC2):c.433G>A (p.Ala145Thr) rs774892845
NM_000548.5(TSC2):c.4346C>T (p.Ser1449Phe) rs759004251
NM_000548.5(TSC2):c.4349C>G (p.Pro1450Arg) rs45517338
NM_000548.5(TSC2):c.4376G>A (p.Arg1459Gln) rs1555514409
NM_000548.5(TSC2):c.4414G>A (p.Gly1472Ser) rs558737770
NM_000548.5(TSC2):c.4426G>A (p.Glu1476Lys) rs376946970
NM_000548.5(TSC2):c.4448G>C (p.Arg1483Thr) rs370114027
NM_000548.5(TSC2):c.4457C>T (p.Ala1486Val) rs773527337
NM_000548.5(TSC2):c.4469A>G (p.Glu1490Gly) rs759882146
NM_000548.5(TSC2):c.446A>G (p.Asn149Ser) rs1029118280
NM_000548.5(TSC2):c.4470G>T (p.Glu1490Asp) rs1221986548
NM_000548.5(TSC2):c.4498G>A (p.Val1500Met) rs397515167
NM_000548.5(TSC2):c.4527C>A (p.Phe1509Leu) rs775919951
NM_000548.5(TSC2):c.454C>G (p.His152Asp) rs397515285
NM_000548.5(TSC2):c.4552A>G (p.Ile1518Val) rs764903148
NM_000548.5(TSC2):c.4565A>T (p.Asn1522Ile) rs144062721
NM_000548.5(TSC2):c.4569+4G>A rs1051944517
NM_000548.5(TSC2):c.4577C>A (p.Ser1526Tyr) rs796053498
NM_000548.5(TSC2):c.457A>G (p.Ile153Val) rs1555497700
NM_000548.5(TSC2):c.4605C>A (p.Asp1535Glu) rs1555515283
NM_000548.5(TSC2):c.4639G>A (p.Val1547Ile) rs745895675
NM_000548.5(TSC2):c.4671C>G (p.Ser1557Arg) rs151140709
NM_000548.5(TSC2):c.4691A>G (p.Asn1564Ser) rs876659806
NM_000548.5(TSC2):c.4764G>C (p.Gln1588His) rs876659800
NM_000548.5(TSC2):c.4806G>T (p.Glu1602Asp) rs1177233720
NM_000548.5(TSC2):c.4823A>C (p.Tyr1608Ser) rs759795928
NM_000548.5(TSC2):c.4834G>T (p.Asp1612Tyr) rs886051795
NM_000548.5(TSC2):c.4840A>C (p.Ile1614Leu) rs1555516299
NM_000548.5(TSC2):c.4847A>G (p.Gln1616Arg) rs1555516313
NM_000548.5(TSC2):c.4849+4C>T rs370426490
NM_000548.5(TSC2):c.4901G>A (p.Arg1634His) rs201694466
NM_000548.5(TSC2):c.4990-3C>T rs777928103
NM_000548.5(TSC2):c.4998C>A (p.Phe1666Leu) rs757221445
NM_000548.5(TSC2):c.499T>C (p.Trp167Arg) rs1555498118
NM_000548.5(TSC2):c.5038T>G (p.Cys1680Gly) rs1555439802
NM_000548.5(TSC2):c.5041A>G (p.Asn1681Asp) rs1200837034
NM_000548.5(TSC2):c.5095G>A (p.Val1699Met) rs370864445
NM_000548.5(TSC2):c.5110T>A (p.Ser1704Thr) rs45474691
NM_000548.5(TSC2):c.5137C>A (p.Arg1713Ser) rs759420443
NM_000548.5(TSC2):c.5143A>G (p.Met1715Val) rs397514974
NM_000548.5(TSC2):c.5155G>A (p.Ala1719Thr) rs201206500
NM_000548.5(TSC2):c.5161-4C>G rs45517406
NM_000548.5(TSC2):c.5177A>C (p.His1726Pro) rs1555440475
NM_000548.5(TSC2):c.5193C>A (p.Asn1731Lys) rs753336580
NM_000548.5(TSC2):c.5197_5211del (p.Thr1733_Pro1737del) rs1555440518
NM_000548.5(TSC2):c.5204T>G (p.Ile1735Ser) rs786203769
NM_000548.5(TSC2):c.5209C>T (p.Pro1737Ser) rs780112037
NM_000548.5(TSC2):c.5220G>T (p.Trp1740Cys) rs45517411
NM_000548.5(TSC2):c.5258G>A (p.Arg1753Gln) rs749487441
NM_000548.5(TSC2):c.5262C>G (p.Ile1754Met) rs397515318
NM_000548.5(TSC2):c.5266G>A (p.Glu1756Lys) rs375075952
NM_000548.5(TSC2):c.5296C>T (p.Pro1766Ser) rs779621136
NM_000548.5(TSC2):c.5299C>G (p.Leu1767Val) rs1051758
NM_000548.5(TSC2):c.5305C>T (p.His1769Tyr) rs1555441265
NM_000548.5(TSC2):c.5311C>G (p.Pro1771Ala) rs777006583
NM_000548.5(TSC2):c.5329C>G (p.Pro1777Ala) rs781226141
NM_000548.5(TSC2):c.5339C>T (p.Thr1780Ile) rs778395191
NM_000548.5(TSC2):c.5378G>A (p.Arg1793Gln) rs45506695
NM_000548.5(TSC2):c.5384G>A (p.Arg1795His) rs137854288
NM_000548.5(TSC2):c.560A>G (p.Asn187Ser) rs45505405
NM_000548.5(TSC2):c.577G>A (p.Glu193Lys) rs45517112
NM_000548.5(TSC2):c.581A>G (p.Tyr194Cys) rs1555498219
NM_000548.5(TSC2):c.583A>G (p.Ile195Val) rs148325559
NM_000548.5(TSC2):c.673G>A (p.Val225Met) rs142919353
NM_000548.5(TSC2):c.695C>T (p.Pro232Leu) rs760100924
NM_000548.5(TSC2):c.704G>C (p.Ser235Thr) rs397514957
NM_000548.5(TSC2):c.709C>T (p.Pro237Ser) rs1555498859
NM_000548.5(TSC2):c.710C>G (p.Pro237Arg) rs139060277
NM_000548.5(TSC2):c.721G>A (p.Val241Ile) rs200943828
NM_000548.5(TSC2):c.733C>T (p.Arg245Cys) rs375574283
NM_000548.5(TSC2):c.775-4G>A rs754957491
NM_000548.5(TSC2):c.782G>A (p.Arg261Gln) rs45502703
NM_000548.5(TSC2):c.821A>G (p.Tyr274Cys) rs1305592691
NM_000548.5(TSC2):c.849-4T>C rs752614339
NM_000548.5(TSC2):c.866C>T (p.Ala289Val) rs755631210
NM_000548.5(TSC2):c.893T>C (p.Phe298Ser) rs747310967
NM_000548.5(TSC2):c.934C>G (p.Leu312Val) rs755368431
NM_000548.5(TSC2):c.934C>T (p.Leu312Phe) rs755368431
NM_000548.5(TSC2):c.944C>T (p.Ser315Leu) rs202082319
NM_000548.5(TSC2):c.976-3C>T rs45517151
NM_000548.5(TSC2):c.97G>A (p.Gly33Ser) rs370230541
NM_000548.5(TSC2):c.989C>T (p.Pro330Leu) rs140910086

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