List of variants in gene TTN reported as benign for Dilated cardiomyopathy 1G

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 109

Download table as spreadsheet

HGVS	dbSNP	gnomAD frequency
NM_001267550.2(TTN):c.67246G>C (p.Ala22416Pro)	rs4145333	0.99572
NM_001267550.2(TTN):c.23223G>A (p.Gln7741=)	rs2562831	0.98238
NM_001267550.2(TTN):c.14610C>T (p.Ser4870=)	rs2742348	0.98231
NM_001267550.2(TTN):c.9879A>G (p.Glu3293=)	rs4894043	0.97302
NM_001267550.2(TTN):c.10256G>A (p.Ser3419Asn)	rs2291310	0.87769
NM_001267550.2(TTN):c.9781G>A (p.Val3261Met)	rs2291311	0.87338
NM_001267550.2(TTN):c.3601A>G (p.Lys1201Glu)	rs10497520	0.69988
NM_001267550.2(TTN):c.31864G>A (p.Gly10622Arg)	rs2244492	0.44551
NM_001267550.2(TTN):c.65682A>G (p.Thr21894=)	rs4894029	0.35796
NM_001267550.2(TTN):c.56101A>G (p.Asn18701Asp)	rs1001238	0.35628
NM_001267550.2(TTN):c.61245A>G (p.Thr20415=)	rs2163009	0.35615
NM_001267550.2(TTN):c.62058T>C (p.Tyr20686=)	rs1560221	0.35601
NM_001267550.2(TTN):c.31564A>G (p.Ile10522Val)	rs2042995	0.35566
NM_001267550.2(TTN):c.105384A>G (p.Ala35128=)	rs3813250	0.35546
NM_001267550.2(TTN):c.83673T>C (p.Gly27891=)	rs2366751	0.35531
NM_001267550.2(TTN):c.83323A>G (p.Ile27775Val)	rs3829746	0.35516
NM_001267550.2(TTN):c.88187T>C (p.Ile29396Thr)	rs9808377	0.35383
NM_001267550.2(TTN):c.97795+6G>T	rs3731750	0.35139
NM_001267550.2(TTN):c.64208C>T (p.Thr21403Ile)	rs2042996	0.34979
NM_001267550.2(TTN):c.26289A>G (p.Glu8763=)	rs2562838	0.33531
NM_001267550.2(TTN):c.2244G>A (p.Glu748=)	rs6715406	0.32532
NM_001267550.2(TTN):c.23099-3T>C	rs2562830	0.31174
NM_001267550.2(TTN):c.26091A>T (p.Leu8697=)	rs2562836	0.29823
NM_001267550.2(TTN):c.26655C>T (p.Ser8885=)	rs2562839	0.29759
NM_001267550.2(TTN):c.25064C>A (p.Ala8355Glu)	rs2627043	0.29094
NM_001267550.2(TTN):c.79862C>T (p.Thr26621Met)	rs3731746	0.24029
NM_001267550.2(TTN):c.67075G>A (p.Val22359Ile)	rs2303838	0.23912
NM_001267550.2(TTN):c.70830C>T (p.Ser23610=)	rs12464787	0.23390
NM_001267550.2(TTN):c.33287G>A (p.Arg11096His)	rs36051007	0.21486
NM_001267550.2(TTN):c.78674T>C (p.Ile26225Thr)	rs12463674	0.21485
NM_001267550.2(TTN):c.57315T>C (p.His19105=)	rs35833641	0.21406
NM_001267550.2(TTN):c.2432C>T (p.Thr811Ile)	rs35813871	0.17564
NM_001267550.2(TTN):c.98098+9T>A	rs2288325	0.16490
NM_001267550.2(TTN):c.104988C>T (p.Val34996=)	rs3829748	0.16457
NM_001267550.2(TTN):c.22384G>C (p.Asp7462His)	rs12693166	0.16435
NM_001267550.2(TTN):c.33834G>A (p.Glu11278=)	rs35112591	0.16327
NM_001267550.2(TTN):c.26408A>G (p.Asn8803Ser)	rs12693164	0.16204
NM_001267550.2(TTN):c.25274G>A (p.Ser8425Asn)	rs13390491	0.16202
NM_001267550.2(TTN):c.24431A>C (p.Glu8144Ala)	rs16866465	0.15861
NM_001267550.2(TTN):c.102519C>T (p.Gly34173=)	rs2857265	0.15539
NM_001267550.2(TTN):c.93243C>T (p.Ala31081=)	rs3731748	0.15537
NM_001267550.2(TTN):c.97613G>A (p.Arg32538His)	rs3731749	0.14445
NM_001267550.2(TTN):c.58436G>A (p.Arg19479His)	rs2288569	0.13356
NM_001267550.2(TTN):c.103781G>A (p.Arg34594His)	rs3829747	0.13294
NM_001267550.2(TTN):c.74839C>T (p.Arg24947Cys)	rs744426	0.13213
NM_001267550.2(TTN):c.92131G>A (p.Val30711Met)	rs747122	0.11550
NM_001267550.2(TTN):c.14525G>A (p.Arg4842Lys)	rs2742347	0.11354
NM_001267550.2(TTN):c.982C>T (p.Arg328Cys)	rs16866538	0.10360
NM_001267550.2(TTN):c.9597A>G (p.Glu3199=)	rs2291312	0.09947
NM_001267550.2(TTN):c.75522A>C (p.Ala25174=)	rs6732060	0.09129
NM_001267550.2(TTN):c.29153T>C (p.Ile9718Thr)	rs4893852	0.08349
NM_001267550.2(TTN):c.26681C>T (p.Pro8894Leu)	rs13398235	0.07839
NM_001267550.2(TTN):c.25921+10C>T	rs10183237	0.07769
NM_001267550.2(TTN):c.42783A>G (p.Lys14261=)	rs16866425	0.07162
NM_001267550.2(TTN):c.29763T>C (p.Ile9921=)	rs2742343	0.06625
NM_001267550.2(TTN):c.71993G>A (p.Arg23998His)	rs10164753	0.06031
NM_001267550.2(TTN):c.22080T>C (p.Asp7360=)	rs16866473	0.05854
NM_001267550.2(TTN):c.79062T>A (p.Gly26354=)	rs3731744	0.05786
NM_001267550.2(TTN):c.107267T>C (p.Val35756Ala)	rs16866378	0.05725
NM_001267550.2(TTN):c.19301G>A (p.Ser6434Asn)	rs11888217	0.05644
NM_001267550.2(TTN):c.3087T>C (p.Tyr1029=)	rs55863869	0.05117
NM_001267550.2(TTN):c.29799G>A (p.Ser9933=)	rs2742344	0.05063
NM_001267550.2(TTN):c.8919C>G (p.Ser2973=)	rs4894045	0.05021
NM_001267550.2(TTN):c.9461A>G (p.Lys3154Arg)	rs4893853	0.05020
NM_001267550.2(TTN):c.8492G>A (p.Ser2831Asn)	rs2306636	0.04907
NM_001267550.2(TTN):c.7830G>C (p.Met2610Ile)	rs56142888	0.04798
NM_001267550.2(TTN):c.88272G>A (p.Glu29424=)	rs9808036	0.04549
NM_001267550.2(TTN):c.28662G>A (p.Arg9554=)	rs2742332	0.04384
NM_001267550.2(TTN):c.76343G>A (p.Ser25448Asn)	rs3813243	0.04071
NM_001267550.2(TTN):c.98912G>A (p.Arg32971His)	rs4894028	0.03961
NM_001267550.2(TTN):c.49731T>C (p.His16577=)	rs2115558	0.03943
NM_001267550.2(TTN):c.102833G>T (p.Gly34278Val)	rs3731752	0.03923
NM_001267550.2(TTN):c.100579G>A (p.Val33527Ile)	rs2278196	0.03742
NM_001267550.2(TTN):c.51482C>T (p.Ala17161Val)	rs16866412	0.03700
NM_001267550.2(TTN):c.30952G>A (p.Glu10318Lys)	rs73038324	0.03639
NM_001267550.2(TTN):c.69145A>G (p.Ile23049Val)	rs72646881	0.03550
NM_001267550.2(TTN):c.93901G>A (p.Val31301Ile)	rs67665715	0.03523
NM_001267550.2(TTN):c.82798G>A (p.Ala27600Thr)	rs11896637	0.03502
NM_001267550.2(TTN):c.25626G>T (p.Gln8542His)	rs2562832	0.02406
NM_001267550.2(TTN):c.25707T>C (p.Tyr8569=)	rs2742329	0.02401
NM_133378.4(TTN):c.93062-10T>C	rs202214630	0.02222
NM_001267550.2(TTN):c.98164A>T (p.Ile32722Phe)	rs72648270	0.01635
NM_001267550.2(TTN):c.92191A>G (p.Ile30731Val)	rs16866391	0.01426
NM_001267550.2(TTN):c.58933C>T (p.Leu19645=)	rs2303836	0.01401
NM_001267550.2(TTN):c.43603C>T (p.Arg14535Cys)	rs12471771	0.00967
NM_001267550.2(TTN):c.14984C>G (p.Pro4995Arg)	rs72648927	0.00729
NM_001267550.2(TTN):c.43596T>C (p.Asn14532=)	rs16866423	0.00691
NM_001267550.2(TTN):c.39709+6C>T	rs72650067	0.00533
NM_001267550.2(TTN):c.79319G>A (p.Arg26440His)	rs56044609	0.00516
NM_001267550.2(TTN):c.30274C>T (p.His10092Tyr)	rs72650011	0.00378
NM_001267550.2(TTN):c.14698G>A (p.Ala4900Thr)	rs72648923	0.00332
NM_001267550.2(TTN):c.94046G>A (p.Arg31349His)	rs181104321	0.00282
NM_001267550.2(TTN):c.103363C>T (p.Arg34455Cys)	rs72629785	0.00238
NM_001267550.2(TTN):c.16621+7A>T	rs10200398	0.00133
NM_001267550.2(TTN):c.91765G>A (p.Ala30589Thr)	rs148617456	0.00108
NM_001267550.2(TTN):c.80322C>T (p.Ala26774=)	rs55892928	0.00094
NM_001267550.2(TTN):c.107576T>C (p.Met35859Thr)	rs72629793	0.00063
NM_001267550.2(TTN):c.3100G>A (p.Val1034Met)	rs142951505	0.00061
NM_001267550.2(TTN):c.10163G>A (p.Arg3388Gln)	rs187703540	0.00039
NM_001267550.2(TTN):c.15552C>T (p.Thr5184=)	rs146353237	0.00024
NM_001267550.2(TTN):c.31645A>G (p.Ile10549Val)	rs376613199	0.00021
NM_001267550.2(TTN):c.57112-4C>T	rs117072049	0.00008
NM_001267550.2(TTN):c.15561G>A (p.Leu5187=)	rs779159076	0.00004
NM_001267550.2(TTN):c.15561G>T (p.Leu5187=)	rs779159076
NM_001267550.2(TTN):c.23023G>T (p.Asp7675Tyr)	rs552951988
NM_001267550.2(TTN):c.39704C>G (p.Pro13235Arg)	rs72650066
NM_001267550.2(TTN):c.76739C>T (p.Thr25580Met)	rs56372592
NM_001267550.2(TTN):c.90968G>A (p.Arg30323Lys)	rs11887722
NM_001267550.2(TTN):c.91071T>G (p.Thr30357=)	rs11897366

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.