List of variants in gene TTR reported as likely benign by Ambry Genetics

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 33

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HGVS	dbSNP	gnomAD frequency
NM_000371.4(TTR):c.416C>T (p.Thr139Met)	rs28933981	0.00177
NM_000371.4(TTR):c.417G>A (p.Thr139=)	rs2276382	0.00104
NM_000371.4(TTR):c.328C>A (p.His110Asn)	rs121918074	0.00038
NM_000371.4(TTR):c.14G>A (p.Arg5His)	rs138657343	0.00017
NM_000371.4(TTR):c.384C>T (p.Ala128=)	rs143906738	0.00013
NM_000371.4(TTR):c.354C>T (p.Asn118=)	rs11541797	0.00009
NM_000371.4(TTR):c.355G>A (p.Asp119Asn)	rs76410435	0.00006
NM_000371.4(TTR):c.411C>T (p.Ser137=)	rs759874627	0.00006
NM_000371.4(TTR):c.437A>G (p.Lys146Arg)	rs536294863	0.00005
NM_000371.4(TTR):c.375C>T (p.Tyr125=)	rs749079577	0.00004
NM_000371.4(TTR):c.405C>G (p.Ser135=)	rs760153126	0.00003
NM_000371.4(TTR):c.78T>C (p.Gly26=)	rs779457244	0.00002
NM_000371.4(TTR):c.121C>A (p.Arg41=)	rs1004021945	0.00001
NM_000371.4(TTR):c.147C>T (p.Ala49=)	rs11081703	0.00001
NM_000371.4(TTR):c.24C>T (p.Leu8=)	rs991342939	0.00001
NM_000371.4(TTR):c.267C>T (p.Tyr89=)	rs757950308	0.00001
NM_000371.4(TTR):c.408T>C (p.Tyr136=)	rs1454790119	0.00001
NM_000371.4(TTR):c.40C>T (p.Leu14=)	rs1347695561	0.00001
NM_000371.4(TTR):c.70-4C>T	rs780910338	0.00001
NM_000371.4(TTR):c.75C>T (p.Thr25=)	rs750051388	0.00001
NM_000371.4(TTR):c.141T>C (p.Asn47=)	rs1252826226
NM_000371.4(TTR):c.156G>A (p.Val52=)	rs2144406775
NM_000371.4(TTR):c.261G>A (p.Gly87=)
NM_000371.4(TTR):c.300G>A (p.Lys100=)	rs2144409644
NM_000371.4(TTR):c.365C>G (p.Pro122Arg)	rs11541793
NM_000371.4(TTR):c.372C>G (p.Arg124=)	rs780119793
NM_000371.4(TTR):c.381T>C (p.Ile127=)	rs751430411
NM_000371.4(TTR):c.387C>A (p.Ala129=)	rs772657903
NM_000371.4(TTR):c.396C>T (p.Ser132=)	rs2144414307
NM_000371.4(TTR):c.420T>C (p.Ala140=)	rs2510934159
NM_000371.4(TTR):c.438G>A (p.Lys146=)	rs2510934166
NM_000371.4(TTR):c.69G>C (p.Thr23=)	rs752579437
NM_000371.4(TTR):c.9T>C (p.Ser3=)	rs1598843600

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