List of variants in gene WFS1 reported as uncertain significance for Monogenic diabetes

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 30

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HGVS	dbSNP	gnomAD frequency
NM_006005.3(WFS1):c.2452C>T (p.Arg818Cys)	rs35932623	0.00390
NM_006005.3(WFS1):c.1554G>A (p.Met518Ile)	rs138232538	0.00202
NM_006005.3(WFS1):c.227G>T (p.Gly76Val)	rs200135768	0.00197
NM_006005.3(WFS1):c.2039A>C (p.Glu680Ala)	rs144840779	0.00050
NM_006005.3(WFS1):c.1610G>A (p.Cys537Tyr)	rs199910987	0.00034
NM_006005.3(WFS1):c.647C>G (p.Pro216Arg)	rs141233896	0.00032
NM_006005.3(WFS1):c.1371G>T (p.Arg457Ser)	rs113446173	0.00030
NM_006005.3(WFS1):c.1124G>A (p.Arg375His)	rs142671083	0.00029
NM_006005.3(WFS1):c.1265C>T (p.Ala422Val)	rs150368988	0.00029
NM_006005.3(WFS1):c.325C>T (p.His109Tyr)	rs112871383	0.00029
NM_006005.3(WFS1):c.2053C>T (p.Arg685Cys)	rs112967046	0.00020
NM_006005.3(WFS1):c.1820C>T (p.Pro607Leu)	rs373862003	0.00019
NM_006005.3(WFS1):c.2122C>T (p.Arg708Cys)	rs200099217	0.00016
NM_006005.3(WFS1):c.400G>A (p.Ala134Thr)	rs147724970	0.00016
NM_006005.3(WFS1):c.728C>T (p.Ala243Val)	rs147147660	0.00012
NM_006005.3(WFS1):c.1052A>G (p.Tyr351Cys)	rs181988441	0.00006
NM_006005.3(WFS1):c.1886G>A (p.Arg629Gln)	rs146670741	0.00006
NM_006005.3(WFS1):c.20C>T (p.Pro7Leu)	rs138165486	0.00004
NM_006005.3(WFS1):c.1896G>T (p.Met632Ile)	rs1057524890	0.00002
NM_006005.3(WFS1):c.2194C>T (p.Arg732Cys)	rs71526458	0.00001
NM_006005.3(WFS1):c.2570C>A (p.Thr857Asn)	rs573202595	0.00001
NM_006005.3(WFS1):c.578A>G (p.Lys193Arg)	rs1005714777	0.00001
NM_006005.3(WFS1):c.1060_1062del (p.Phe354del)	rs876657735
NM_006005.3(WFS1):c.1135G>T (p.Asp379Tyr)	rs772554352
NM_006005.3(WFS1):c.1294C>G (p.Leu432Val)	rs35031397
NM_006005.3(WFS1):c.172G>A (p.Ala58Thr)	rs1057524887
NM_006005.3(WFS1):c.1868T>A (p.Met623Lys)	rs758746685
NM_006005.3(WFS1):c.2385G>C (p.Glu795Asp)	rs373310972
NM_006005.3(WFS1):c.667C>A (p.Leu223Met)	rs1057524889
NM_006005.3(WFS1):c.979C>A (p.Leu327Ile)	rs71537678

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