ClinVar Miner

List of variants in gene WRN reported as likely benign for not provided

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Gene type:
ClinVar version:
Total variants: 76
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HGVS dbSNP gnomAD frequency
NM_000553.6(WRN):c.1269+204C>G rs2725381 0.04227
NM_000553.6(WRN):c.1350+115dup rs11574230 0.01866
NM_000553.6(WRN):c.3820-49G>A rs11574384 0.01440
NM_000553.6(WRN):c.2967+244A>G rs11574334 0.01372
NM_000553.6(WRN):c.2826-207C>T rs11574333 0.01367
NM_000553.6(WRN):c.1982-156T>C rs11574272 0.01366
NM_000553.6(WRN):c.3573-130G>T rs11574371 0.01255
NM_000553.6(WRN):c.1577-294A>G rs11574239 0.01212
NM_000553.6(WRN):c.724+74C>T rs3087408 0.01112
NM_000553.6(WRN):c.1270-60_1270-32del rs11574229 0.01082
NM_000553.6(WRN):c.2631-17A>C rs3087433 0.01054
NM_000553.6(WRN):c.654+135C>A rs11574205 0.01007
NM_000553.6(WRN):c.2732+19A>G rs77434316 0.00923
NM_000553.6(WRN):c.209+129C>T rs76077884 0.00813
NM_000553.6(WRN):c.654+216A>G rs76337727 0.00807
NM_000553.6(WRN):c.1829+254T>C rs111241363 0.00710
NM_000553.6(WRN):c.3234-141A>G rs139326961 0.00679
NM_000553.6(WRN):c.654+210T>C rs114641318 0.00674
NM_000553.6(WRN):c.3310-306C>T rs117801356 0.00601
NM_000553.6(WRN):c.2273+135C>T rs149280471 0.00540
NM_000553.6(WRN):c.1982-135T>A rs181046205 0.00538
NM_000553.6(WRN):c.1898+65C>T rs115351572 0.00518
NM_000553.6(WRN):c.1725T>C (p.Tyr575=) rs13438802 0.00516
NM_000553.6(WRN):c.1788T>C (p.Ser596=) rs13438803 0.00512
NM_000553.6(WRN):c.3459+66A>G rs146471227 0.00508
NM_000553.6(WRN):c.2273+299A>G rs144437633 0.00505
NM_000553.6(WRN):c.3983-39G>A rs145212074 0.00500
NM_000553.6(WRN):c.4015G>A (p.Val1339Ile) rs11574395 0.00418
NM_000553.6(WRN):c.*194C>T rs11574411 0.00413
NM_000553.6(WRN):c.724+120A>G rs113947509 0.00398
NM_000553.6(WRN):c.1577-17T>G rs145080962 0.00363
NM_000553.6(WRN):c.1431+149T>A rs146967731 0.00362
NM_000553.6(WRN):c.3820-101C>T rs189096241 0.00361
NM_000553.6(WRN):c.95A>G (p.Lys32Arg) rs34477820 0.00310
NM_000553.6(WRN):c.3785C>G (p.Thr1262Arg) rs78488552 0.00276
NM_000553.6(WRN):c.970A>G (p.Thr324Ala) rs1800390 0.00245
NM_000553.6(WRN):c.2983G>A (p.Ala995Thr) rs140768346 0.00193
NM_000553.6(WRN):c.355+4G>C rs145764920 0.00156
NM_000553.6(WRN):c.1149G>T (p.Leu383Phe) rs4987238 0.00148
NM_000553.6(WRN):c.3875C>A (p.Ser1292Tyr) rs142614369 0.00132
NM_000553.6(WRN):c.107G>A (p.Arg36Gln) rs34084741 0.00091
NM_000553.6(WRN):c.3900C>A (p.Pro1300=) rs138886038 0.00089
NM_000553.6(WRN):c.3453G>A (p.Glu1151=) rs144116311 0.00054
NM_000553.6(WRN):c.3738G>A (p.Leu1246=) rs147117969 0.00045
NM_000553.6(WRN):c.1989G>A (p.Thr663=) rs201982706 0.00038
NM_000553.6(WRN):c.2256A>G (p.Pro752=) rs372016270 0.00012
NM_000553.6(WRN):c.3591C>T (p.Asn1197=) rs151143960 0.00010
NM_000553.6(WRN):c.2940G>C (p.Gly980=) rs374522855 0.00009
NM_000553.6(WRN):c.75A>G (p.Arg25=) rs150524008 0.00006
NM_000553.6(WRN):c.2735T>G (p.Ile912Ser) rs11574323 0.00005
NM_000553.6(WRN):c.1341G>A (p.Glu447=) rs200380997 0.00004
NM_000553.6(WRN):c.744C>T (p.Ser248=) rs370071444 0.00004
NM_000553.6(WRN):c.3417T>C (p.Ser1139=) rs752542644 0.00002
NM_000553.6(WRN):c.3123C>T (p.Cys1041=) rs773664315 0.00001
NM_000553.6(WRN):c.516A>G (p.Thr172=) rs1271302052 0.00001
NM_000553.6(WRN):c.108G>A (p.Arg36=) rs1385455441
NM_000553.6(WRN):c.1247A>G (p.Asp416Gly) rs560922465
NM_000553.6(WRN):c.1431+168G>A rs147561551
NM_000553.6(WRN):c.1431+236del rs1038655830
NM_000553.6(WRN):c.1518AGA[3] (p.Glu509_Glu510del) rs781777438
NM_000553.6(WRN):c.1899-10G>T rs748285435
NM_000553.6(WRN):c.1982-5del rs397723919
NM_000553.6(WRN):c.2089-3135del
NM_000553.6(WRN):c.210-53C>T rs6983980
NM_000553.6(WRN):c.2274-207del
NM_000553.6(WRN):c.2574T>C (p.Asp858=)
NM_000553.6(WRN):c.261A>G (p.Pro87=) rs2130032327
NM_000553.6(WRN):c.2630+139T>G rs11574314
NM_000553.6(WRN):c.2631-236_2631-234del
NM_000553.6(WRN):c.2706T>C (p.Tyr902=) rs1801848281
NM_000553.6(WRN):c.3282A>T (p.Val1094=)
NM_000553.6(WRN):c.3411T>A (p.Ala1137=)
NM_000553.6(WRN):c.3438G>C (p.Ser1146=)
NM_000553.6(WRN):c.355+91C>T rs11574198
NM_000553.6(WRN):c.4191+182A>T rs117133984
NM_000553.6(WRN):c.725-260T>C rs2737321

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