List of variants in gene WRN reported as uncertain significance by Fulgent Genetics, Fulgent Genetics

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 26

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HGVS	dbSNP	gnomAD frequency
NM_000553.6(WRN):c.3875C>A (p.Ser1292Tyr)	rs142614369	0.00132
NM_000553.6(WRN):c.130C>G (p.Leu44Val)	rs139775895	0.00031
NM_000553.6(WRN):c.3259A>G (p.Lys1087Glu)	rs374154973	0.00028
NM_000553.6(WRN):c.2986G>A (p.Asp996Asn)	rs138379977	0.00026
NM_000553.6(WRN):c.1382C>T (p.Thr461Met)	rs371602600	0.00020
NM_000553.6(WRN):c.4127C>T (p.Pro1376Leu)	rs146055899	0.00010
NM_000553.6(WRN):c.3623A>G (p.Lys1208Arg)	rs529421538	0.00009
NM_000553.6(WRN):c.1840A>G (p.Ile614Val)	rs577000913	0.00008
NM_000553.6(WRN):c.3819+5G>C	rs770289356	0.00008
NM_000553.6(WRN):c.1388A>G (p.Tyr463Cys)	rs1339450958	0.00004
NM_000553.6(WRN):c.2263G>A (p.Val755Ile)	rs769448856	0.00004
NM_000553.6(WRN):c.3284C>T (p.Pro1095Leu)	rs746470648	0.00004
NM_000553.6(WRN):c.3778G>A (p.Ala1260Thr)	rs201107091	0.00004
NM_000553.6(WRN):c.674G>A (p.Arg225Gln)	rs62506077	0.00004
NM_000553.6(WRN):c.1652C>T (p.Pro551Leu)	rs781107893	0.00003
NM_000553.6(WRN):c.2098G>A (p.Val700Ile)	rs1038838933	0.00003
NM_000553.6(WRN):c.2978G>A (p.Arg993His)	rs370713742	0.00003
NM_000553.6(WRN):c.4001T>G (p.Leu1334Arg)	rs200403732	0.00003
NM_000553.6(WRN):c.1457C>T (p.Thr486Met)	rs761328537	0.00001
NM_000553.6(WRN):c.655-20A>G	rs1056118121	0.00001
NM_000553.6(WRN):c.725-3del	rs778493200	0.00001
NM_000553.6(WRN):c.202G>T (p.Asp68Tyr)	rs2130005767
NM_000553.6(WRN):c.3209_3211delinsTTT (p.Cys1070_Pro1071delinsPheSer)	rs878854138
NM_000553.6(WRN):c.3814C>T (p.Pro1272Ser)	rs776989868
NM_000553.6(WRN):c.4011G>A (p.Met1337Ile)	rs544317387
NM_000553.6(WRN):c.836G>C (p.Arg279Pro)	rs768400363

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