ClinVar Miner

Variants in gene XRCC2

Minimum submission review status: Collection method:
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If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign total
5 8 89 65 12 165

Condition and significance breakdown #

Total conditions: 9
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Condition pathogenic likely pathogenic uncertain significance likely benign benign total
not specified 0 0 28 53 10 83
not provided 1 8 56 0 0 65
Hereditary cancer-predisposing syndrome 2 1 13 19 2 36
Hereditary Cancer Syndrome 0 0 15 1 0 16
Fanconi anemia, complementation group U 0 0 3 0 0 3
Colon cancer 0 0 1 0 0 1
Colorectal cancer 0 0 1 0 0 1
Hereditary breast and ovarian cancer syndrome 1 0 0 0 0 1
Ovarian Neoplasms 1 0 0 0 0 1

Submitter and significance breakdown #

Total submitters: 14
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Submitter pathogenic likely pathogenic uncertain significance likely benign benign total
GeneDx 1 8 61 48 8 126
Invitae 0 0 21 4 3 28
Ambry Genetics 2 0 8 12 2 24
Mendelics 0 0 15 1 0 16
University of Washington Department of Laboratory Medicine,University of Washington 0 0 3 7 0 10
GeneKor MSA 0 1 2 0 0 3
Genetic Services Laboratory, University of Chicago 0 0 1 1 0 2
EGL Genetic Diagnostics,Eurofins Clinical Diagnostics 0 0 2 0 0 2
Fulgent Genetics 0 0 2 0 0 2
CSER_CC_NCGL; University of Washington Medical Center 0 0 2 0 0 2
OMIM 0 0 1 0 0 1
CeGaT Praxis fuer Humangenetik Tuebingen 0 0 1 0 0 1
Genomics Laboratory,Virgen de la Arrixaca University Clinical Hospital 1 0 0 0 0 1
German Consortium for Hereditary Breast and Ovarian Cancer Center Cologne,University Hospital Cologne 1 0 0 0 0 1

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