ClinVar Miner

Variants in gene ZEB2

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Minimum submission review status: Collection method:
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Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign total
137 13 161 174 52 476

Condition and significance breakdown #

Total conditions: 10
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Condition pathogenic likely pathogenic uncertain significance likely benign benign total
Mowat-Wilson syndrome 86 9 113 69 28 289
not specified 0 0 12 111 38 147
not provided 58 3 45 8 7 119
History of neurodevelopmental disorder 1 0 6 28 7 42
Inborn genetic diseases 3 0 0 0 0 3
Abnormality of brain morphology 0 1 0 0 0 1
Hirschsprung disease-mental retardation syndrome, late infantile 1 0 0 0 0 1
Lennox-Gastaut syndrome 0 0 1 0 0 1
See cases 0 0 0 0 1 1
Smith-Magenis Syndrome-like 1 0 0 0 0 1

Submitter and significance breakdown #

Total submitters: 34
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Submitter pathogenic likely pathogenic uncertain significance likely benign benign total
GeneDx 37 0 25 96 35 193
Invitae 16 1 50 29 22 118
Illumina Clinical Services Laboratory,Illumina 0 0 50 40 7 97
EGL Genetic Diagnostics,Eurofins Clinical Diagnostics 26 1 17 8 18 70
Genetic Services Laboratory, University of Chicago 17 0 14 12 12 55
Ambry Genetics 4 0 6 28 7 45
Molecular Genetics Laboratory,Children's Mercy Hospital and Clinics 31 0 0 2 1 34
OMIM 15 0 0 0 0 15
Center for Pediatric Genomic Medicine,Children's Mercy Hospital and Clinics 2 0 0 4 6 12
Division of Genomic Diagnostics,The Children's Hospital of Philadelphia 5 0 1 2 1 9
Athena Diagnostics Inc 0 0 4 1 3 8
Center for Human Genetics, Inc 1 4 0 3 0 8
CeGaT Praxis fuer Humangenetik Tuebingen 0 1 4 0 0 5
Fulgent Genetics 1 0 3 0 0 4
Baylor Miraca Genetics Laboratories, 3 0 0 0 0 3
HudsonAlpha Institute for Biotechnology 2 1 0 0 0 3
PreventionGenetics 0 0 0 1 1 2
UCLA Clinical Genomics Center, UCLA 0 2 0 0 0 2
Lupski Lab, Baylor-Hopkins CMG,Baylor College of Medicine 1 1 0 0 0 2
Laboratory of Molecular Genetics (Pr. Bezieau's lab),CHU de Nantes 0 1 0 1 0 2
Center for Genomics, Ann and Robert H. Lurie Children's Hospital of Chicago 0 0 2 0 0 2
Clinical Molecular Genetics Laboratory,Johns Hopkins All Children's Hospital 0 0 1 0 0 1
Molecular Genetics Laboratory,BC Children's and BC Women's Hospitals 1 0 0 0 0 1
Mendelics 1 0 0 0 0 1
Quest Diagnostics Nichols Institute San Juan Capistrano 1 0 0 0 0 1
Institute of Human Genetics,Klinikum rechts der Isar 1 0 0 0 0 1
ISCA site 6 0 0 0 0 1 1
Soonchunhyang University Bucheon Hospital,Soonchunhyang University Medical Center 0 0 1 0 0 1
Center for Human Genetics and Laboratory Diagnostics, Dr. Klein, Dr. Rost and Colleagues 1 0 0 0 0 1
Equipe Genetique des Anomalies du Developpement,Université de Bourgogne 0 1 0 0 0 1
Groupe Hospitalier Pitie Salpetriere, UF Genomique du Developpement,Assistance Publique Hopitaux de Paris 1 0 0 0 0 1
Diagnostic Laboratory, Department of Genetics,University Medical Center Groningen 0 0 0 0 1 1
Laboratory of Genetics and Genomics,Cincinnati Children's Hospital Medical Center 0 0 1 0 0 1
Biochemistry Laboratory of CDMU,Chengde Medical University 1 0 0 0 0 1

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