ClinVar Miner

Variants in gene ZFYVE26

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Minimum submission review status: Collection method:
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Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign total
20 46 190 72 50 321

Condition and significance breakdown #

Total conditions: 8
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Condition pathogenic likely pathogenic uncertain significance likely benign benign total
Spastic paraplegia 5 1 55 22 38 121
Spastic Paraplegia, Recessive 0 0 85 18 6 109
Spastic paraplegia 15 10 40 31 1 1 80
not specified 0 0 10 43 31 74
not provided 7 5 31 5 13 60
Hereditary spastic paraplegia 1 0 1 0 0 2
Inborn genetic diseases 0 2 0 0 0 2
Retinal dystrophy 0 0 1 0 0 1

Submitter and significance breakdown #

Total submitters: 22
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Submitter pathogenic likely pathogenic uncertain significance likely benign benign total
Invitae 5 1 55 22 38 121
Illumina Clinical Services Laboratory,Illumina 0 0 88 18 6 112
GeneDx 2 4 4 32 27 69
Counsyl 2 38 23 0 0 63
Athena Diagnostics Inc 2 0 12 7 24 45
EGL Genetic Diagnostics,Eurofins Clinical Diagnostics 3 0 15 3 3 24
Genetic Services Laboratory, University of Chicago 0 0 2 8 0 10
CeGaT Praxis fuer Humangenetik Tuebingen 0 0 8 0 0 8
OMIM 6 0 0 0 0 6
Fulgent Genetics 1 1 4 0 0 6
Ambry Genetics 0 2 0 0 0 2
Institute of Human Genetics,Cologne University 1 1 0 0 0 2
Molecular Genetics Laboratory,BC Children's and BC Women's Hospitals 0 1 1 0 0 2
Center for Pediatric Genomic Medicine,Children's Mercy Hospital and Clinics 0 1 0 1 0 2
Unit for Genetic & Epidemiological Research on Neurological Disorders,Instituto de Investigação e Inovação em Saúde 1 0 1 0 0 2
DNA and Cytogenetics Diagnostics Unit,Erasmus Medical Center 0 0 0 1 1 2
Baylor Miraca Genetics Laboratories, 1 0 0 0 0 1
Genome Diagnostics Laboratory,University Medical Center Utrecht 0 0 0 0 1 1
Mayo Clinic Genetic Testing Laboratories,Mayo Clinic 0 0 1 0 0 1
Genomic Research Center,Shahid Beheshti University of Medical Sciences 0 0 1 0 0 1
Centre for Mendelian Genomics,University Medical Centre Ljubljana 0 0 1 0 0 1
Diagnostic Laboratory, Department of Genetics,University Medical Center Groningen 0 0 0 1 0 1

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