List of variants in gene GNAO1 reported as likely benign for complex neurodevelopmental disorder

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 164

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HGVS	dbSNP	gnomAD frequency
NM_020988.3(GNAO1):c.593+12A>C	rs370265621	0.00036
NM_020988.3(GNAO1):c.474C>T (p.Asp158=)	rs144771965	0.00032
NM_020988.3(GNAO1):c.27G>A (p.Glu9=)	rs139334934	0.00031
NM_020988.3(GNAO1):c.828C>T (p.Gly276=)	rs199741926	0.00028
NM_020988.3(GNAO1):c.195C>T (p.Asp65=)	rs368113345	0.00013
NM_020988.3(GNAO1):c.660G>A (p.Thr220=)	rs189380751	0.00012
NM_020988.3(GNAO1):c.75G>A (p.Glu25=)	rs182812404	0.00007
NM_020988.3(GNAO1):c.118+8C>T	rs372787855	0.00006
NM_020988.3(GNAO1):c.186C>T (p.Ser62=)	rs200201305	0.00006
NM_020988.3(GNAO1):c.389G>A (p.Arg130Gln)	rs200127285	0.00006
NM_020988.3(GNAO1):c.606C>T (p.Val202=)	rs150641952	0.00006
NM_020988.3(GNAO1):c.723+11T>C	rs1436583224	0.00006
NM_020988.3(GNAO1):c.1020C>T (p.Thr340=)	rs765996386	0.00004
NM_020988.3(GNAO1):c.279C>T (p.Ile93=)	rs749909537	0.00004
NM_020988.3(GNAO1):c.386T>C (p.Met129Thr)	rs200539902	0.00004
NM_020988.3(GNAO1):c.464+19G>A	rs373227432	0.00004
NM_020988.3(GNAO1):c.870A>G (p.Glu290=)	rs145546431	0.00004
NM_020988.3(GNAO1):c.1008C>T (p.Phe336=)	rs763429802	0.00003
NM_020988.3(GNAO1):c.309C>T (p.Asp103=)	rs372103298	0.00003
NM_020988.3(GNAO1):c.351C>T (p.Thr117=)	rs770385484	0.00003
NM_020988.3(GNAO1):c.498C>T (p.Ala166=)	rs774947928	0.00003
NM_020988.3(GNAO1):c.897C>T (p.Asp299=)	rs148878451	0.00003
NM_020988.3(GNAO1):c.987G>A (p.Thr329=)	rs201638233	0.00003
NM_020988.3(GNAO1):c.1014C>T (p.Ala338=)	rs369818930	0.00002
NM_020988.3(GNAO1):c.21A>G (p.Ala7=)	rs1396370689	0.00002
NM_020988.3(GNAO1):c.252C>T (p.Ile84=)	rs756947463	0.00002
NM_020988.3(GNAO1):c.393C>G (p.Leu131=)	rs766107260	0.00002
NM_020988.3(GNAO1):c.417G>A (p.Glu139=)	rs369305192	0.00002
NM_020988.3(GNAO1):c.543A>G (p.Lys181=)	rs761449625	0.00002
NM_020988.3(GNAO1):c.724-20C>T	rs774930699	0.00002
NM_020988.3(GNAO1):c.724-4G>A	rs373051247	0.00002
NM_020988.3(GNAO1):c.744C>T (p.Leu248=)	rs377336410	0.00002
NM_020988.3(GNAO1):c.825T>C (p.Phe275=)	rs778172059	0.00002
NM_020988.3(GNAO1):c.903C>T (p.Ala301=)	rs543764725	0.00002
NM_020988.3(GNAO1):c.936C>T (p.Asn312=)	rs200323041	0.00002
NM_020988.3(GNAO1):c.1011C>T (p.Asp337=)	rs375683292	0.00001
NM_020988.3(GNAO1):c.119-17T>C	rs759192540	0.00001
NM_020988.3(GNAO1):c.119-5A>G	rs775212759	0.00001
NM_020988.3(GNAO1):c.132A>G (p.Ser44=)	rs1461948245	0.00001
NM_020988.3(GNAO1):c.161+12T>G	rs761912841	0.00001
NM_020988.3(GNAO1):c.161+13G>T	rs767965127	0.00001
NM_020988.3(GNAO1):c.161+9C>T	rs751608846	0.00001
NM_020988.3(GNAO1):c.257G>A (p.Arg86Gln)	rs1301302019	0.00001
NM_020988.3(GNAO1):c.267C>T (p.Asp89=)	rs201728736	0.00001
NM_020988.3(GNAO1):c.333G>A (p.Val111=)	rs61758988	0.00001
NM_020988.3(GNAO1):c.495C>T (p.Ala165=)	rs745503611	0.00001
NM_020988.3(GNAO1):c.549T>G (p.Thr183=)	rs767417261	0.00001
NM_020988.3(GNAO1):c.54G>A (p.Ala18=)	rs1288429932	0.00001
NM_020988.3(GNAO1):c.593+17C>A	rs778086425	0.00001
NM_020988.3(GNAO1):c.616C>A (p.Arg206=)	rs2037743862	0.00001
NM_020988.3(GNAO1):c.66C>T (p.Asn22=)	rs1215228286	0.00001
NM_020988.3(GNAO1):c.678C>T (p.Val226=)	rs760476691	0.00001
NM_020988.3(GNAO1):c.681G>A (p.Ala227=)	rs770769352	0.00001
NM_020988.3(GNAO1):c.714C>T (p.Asp238=)	rs752775959	0.00001
NM_020988.3(GNAO1):c.724-5C>T	rs529454065	0.00001
NM_020988.3(GNAO1):c.735C>T (p.His245=)	rs201930720	0.00001
NM_020988.3(GNAO1):c.753C>T (p.Phe251=)	rs755484788	0.00001
NM_020988.3(GNAO1):c.783C>T (p.Ile261=)	rs752997228	0.00001
NM_020988.3(GNAO1):c.877+20G>A	rs1222479179	0.00001
NM_020988.3(GNAO1):c.878-10C>G	rs374412223	0.00001
NM_020988.3(GNAO1):c.102G>T (p.Val34=)
NM_020988.3(GNAO1):c.1044C>G (p.Leu348=)
NM_020988.3(GNAO1):c.1053C>T (p.Cys351=)
NM_020988.3(GNAO1):c.111C>T (p.Leu37=)
NM_020988.3(GNAO1):c.118+20C>A
NM_020988.3(GNAO1):c.118+20C>T
NM_020988.3(GNAO1):c.118+3A>G
NM_020988.3(GNAO1):c.118+9C>T
NM_020988.3(GNAO1):c.119-12G>A	rs2143271938
NM_020988.3(GNAO1):c.119-14C>G	rs769634112
NM_020988.3(GNAO1):c.119-18C>T
NM_020988.3(GNAO1):c.129A>G (p.Glu43=)	rs2036187726
NM_020988.3(GNAO1):c.135A>G (p.Gly45=)
NM_020988.3(GNAO1):c.153G>A (p.Lys51=)	rs1555499801
NM_020988.3(GNAO1):c.161+14G>T
NM_020988.3(GNAO1):c.161+16A>G
NM_020988.3(GNAO1):c.161+8C>G	rs145872570
NM_020988.3(GNAO1):c.168C>T (p.Ile56=)
NM_020988.3(GNAO1):c.174A>G (p.Glu58=)	rs1165660073
NM_020988.3(GNAO1):c.201A>G (p.Lys67=)	rs2143520908
NM_020988.3(GNAO1):c.204G>A (p.Gln68=)	rs1452910276
NM_020988.3(GNAO1):c.24G>A (p.Glu8=)	rs2143270247
NM_020988.3(GNAO1):c.261C>T (p.Ala87=)	rs2143521053
NM_020988.3(GNAO1):c.282A>G (p.Glu94=)	rs2037058709
NM_020988.3(GNAO1):c.303+13G>A
NM_020988.3(GNAO1):c.303+7C>A
NM_020988.3(GNAO1):c.303+9C>T
NM_020988.3(GNAO1):c.304-7C>T	rs778867051
NM_020988.3(GNAO1):c.319G>C (p.Val107Leu)
NM_020988.3(GNAO1):c.321G>T (p.Val107=)
NM_020988.3(GNAO1):c.330G>C (p.Val110=)	rs1596867599
NM_020988.3(GNAO1):c.33C>T (p.Ala11=)	rs1243993397
NM_020988.3(GNAO1):c.351C>G (p.Thr117=)	rs770385484
NM_020988.3(GNAO1):c.357C>A (p.Pro119=)
NM_020988.3(GNAO1):c.36C>T (p.Ala12=)	rs1596787365
NM_020988.3(GNAO1):c.372G>C (p.Leu124=)
NM_020988.3(GNAO1):c.387G>A (p.Met129Ile)
NM_020988.3(GNAO1):c.390G>A (p.Arg130=)
NM_020988.3(GNAO1):c.427C>T (p.Arg143Trp)	rs2143647269
NM_020988.3(GNAO1):c.464+12A>G
NM_020988.3(GNAO1):c.464+14C>T	rs745893559
NM_020988.3(GNAO1):c.464+14dup
NM_020988.3(GNAO1):c.464+15G>A	rs770008390
NM_020988.3(GNAO1):c.464+7G>A	rs2037660949
NM_020988.3(GNAO1):c.465-4T>C	rs755412219
NM_020988.3(GNAO1):c.469C>T (p.Leu157=)
NM_020988.3(GNAO1):c.480G>A (p.Leu160=)
NM_020988.3(GNAO1):c.492G>C (p.Gly164=)
NM_020988.3(GNAO1):c.498C>G (p.Ala166=)
NM_020988.3(GNAO1):c.525C>T (p.Ile175=)
NM_020988.3(GNAO1):c.534C>T (p.Thr178=)
NM_020988.3(GNAO1):c.537G>A (p.Arg179=)
NM_020988.3(GNAO1):c.540C>A (p.Val180=)	rs2143660697
NM_020988.3(GNAO1):c.555C>A (p.Ile185=)
NM_020988.3(GNAO1):c.570C>T (p.Phe190=)
NM_020988.3(GNAO1):c.585C>T (p.Leu195=)	rs1289428537
NM_020988.3(GNAO1):c.593+10A>G	rs1596871500
NM_020988.3(GNAO1):c.593+14A>G	rs2143660872
NM_020988.3(GNAO1):c.593+16G>A
NM_020988.3(GNAO1):c.593+19C>A
NM_020988.3(GNAO1):c.593+9C>T
NM_020988.3(GNAO1):c.594-10C>T
NM_020988.3(GNAO1):c.594-15C>A	rs747946596
NM_020988.3(GNAO1):c.594-20C>T
NM_020988.3(GNAO1):c.594-6C>T
NM_020988.3(GNAO1):c.603C>T (p.Asp201=)	rs1385035890
NM_020988.3(GNAO1):c.612C>G (p.Gly204=)	rs768258979
NM_020988.3(GNAO1):c.621T>G (p.Ser207=)	rs2143664918
NM_020988.3(GNAO1):c.639C>A (p.Ile213=)
NM_020988.3(GNAO1):c.648C>T (p.Phe216=)
NM_020988.3(GNAO1):c.681G>T (p.Ala227=)
NM_020988.3(GNAO1):c.720C>T (p.Thr240=)
NM_020988.3(GNAO1):c.723+10C>T
NM_020988.3(GNAO1):c.723+14G>C
NM_020988.3(GNAO1):c.723+14del
NM_020988.3(GNAO1):c.723+15C>T
NM_020988.3(GNAO1):c.723+20C>T
NM_020988.3(GNAO1):c.723+9C>T
NM_020988.3(GNAO1):c.724-10G>A
NM_020988.3(GNAO1):c.724-16C>T
NM_020988.3(GNAO1):c.754G>A (p.Asp252Asn)	rs2037920339
NM_020988.3(GNAO1):c.756C>T (p.Asp252=)
NM_020988.3(GNAO1):c.759C>T (p.Ser253=)
NM_020988.3(GNAO1):c.768C>T (p.Asn256=)
NM_020988.3(GNAO1):c.768CAA[1] (p.Asn257del)	rs1567496374
NM_020988.3(GNAO1):c.789C>G (p.Thr263=)	rs1265902011
NM_020988.3(GNAO1):c.793A>G (p.Ile265Val)	rs2037920534
NM_020988.3(GNAO1):c.804C>T (p.Phe268=)
NM_020988.3(GNAO1):c.820C>A (p.Leu274Ile)
NM_020988.3(GNAO1):c.843G>A (p.Lys281=)
NM_020988.3(GNAO1):c.84C>T (p.Ile28=)
NM_020988.3(GNAO1):c.877+19T>C
NM_020988.3(GNAO1):c.877+7G>C
NM_020988.3(GNAO1):c.877+7G>T	rs1596881898
NM_020988.3(GNAO1):c.878-13T>C
NM_020988.3(GNAO1):c.878-18T>C
NM_020988.3(GNAO1):c.878-7G>C	rs1370200465
NM_020988.3(GNAO1):c.888C>G (p.Thr296=)
NM_020988.3(GNAO1):c.909C>T (p.Tyr303=)	rs773032912
NM_020988.3(GNAO1):c.914A>G (p.Gln305Arg)
NM_020988.3(GNAO1):c.939C>T (p.Arg313=)	rs2037954101
NM_020988.3(GNAO1):c.960T>C (p.Tyr320=)
NM_020988.3(GNAO1):c.96A>G (p.Lys32=)
NM_020988.3(GNAO1):c.9T>C (p.Cys3=)

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