List of variants in gene BRCA1 reported as pathogenic for gastric cancer

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 31

Download table as spreadsheet

HGVS	dbSNP	gnomAD frequency
NM_007294.4(BRCA1):c.5096G>A (p.Arg1699Gln)	rs41293459	0.00001
NM_007294.4(BRCA1):c.5278-1G>C	rs80358099	0.00001
NM_007294.4(BRCA1):c.5503C>T (p.Arg1835Ter)	rs41293465	0.00001
NM_007294.4(BRCA1):c.188T>A (p.Leu63Ter)	rs80357086
NM_007294.4(BRCA1):c.190T>C (p.Cys64Arg)	rs80357064
NM_007294.4(BRCA1):c.2075_2076del (p.His692fs)	rs397508936
NM_007294.4(BRCA1):c.2389_2390del (p.Glu797fs)	rs80357695
NM_007294.4(BRCA1):c.2551G>T (p.Glu851Ter)	rs398122662
NM_007294.4(BRCA1):c.2767_2770del (p.Val923fs)	rs80357661
NM_007294.4(BRCA1):c.2860_2864del (p.Leu954fs)	rs1597867185
NM_007294.4(BRCA1):c.302-2A>C	rs80358011
NM_007294.4(BRCA1):c.3100_3101del (p.Asn1034fs)
NM_007294.4(BRCA1):c.3122C>G (p.Ser1041Ter)	rs397509035
NM_007294.4(BRCA1):c.321del (p.Phe107fs)	rs80357544
NM_007294.4(BRCA1):c.342_343del (p.Ser114_Pro115insTer)	rs80357881
NM_007294.4(BRCA1):c.4335_4338dup (p.Gln1447fs)	rs397509164
NM_007294.4(BRCA1):c.456_457del (p.Ser153fs)	rs80357882
NM_007294.4(BRCA1):c.4579G>T (p.Glu1527Ter)
NM_007294.4(BRCA1):c.4957G>T (p.Val1653Leu)	rs80357261
NM_007294.4(BRCA1):c.4964C>T (p.Ser1655Phe)	rs80357390
NM_007294.4(BRCA1):c.5030_5033del (p.Thr1677fs)	rs80357580
NM_007294.4(BRCA1):c.5092G>T (p.Glu1698Ter)	rs2051929740
NM_007294.4(BRCA1):c.5154G>T (p.Trp1718Cys)	rs80357239
NM_007294.4(BRCA1):c.5161C>T (p.Gln1721Ter)	rs878854957
NM_007294.4(BRCA1):c.5445G>A (p.Trp1815Ter)	rs397509284
NM_007294.4(BRCA1):c.5558A>G (p.Tyr1853Cys)	rs80357258
NM_007294.4(BRCA1):c.593+1G>A	rs1567804153
NM_007294.4(BRCA1):c.603del (p.Gln202fs)
NM_007294.4(BRCA1):c.616C>T (p.Gln206Ter)	rs397509301
NM_007294.4(BRCA1):c.670+1G>T	rs398122706
NM_007294.4(BRCA1):c.81-1G>A	rs80358018

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.