ClinVar Miner

List of variants in gene ZBTB10 reported as uncertain significance for astigmatism

Included ClinVar conditions (10):

Astigmatism; Autistic behavior; Myopia; Impaired social interactions; Aplasia/Hypoplasia of the inner ear
Astigmatism; Congenital ocular coloboma; Patent foramen ovale; Premature birth; Abnormality of the face
Astigmatism; Cystoid macular edema; Abnormal electroretinogram; Pigmentary retinopathy; Dyschromatopsia; Abnormality of retinal pigmentation; Electronegative electroretinogram
Astigmatism; Epicanthus; Cryptorchidism; Hypertelorism; Esotropia; Global developmental delay; Retrognathia; Hypermetropia; Wide nasal bridge; Intellectual disability
Astigmatism; Global developmental delay; Failure to thrive; Micrognathia; Thin vermilion border; Narrow mouth; Anxiety; Attention deficit hyperactivity disorder
Astigmatism; Hamartoma of hypothalamus; Global developmental delay; Nystagmus; Hypermetropia; Opsoclonus
Astigmatism; Leukodystrophy; Motor delay; Seizure; Short stature; Hypermetropia; Delayed speech and language development; Open mouth; Microcephaly; Strabismus; Amblyopia; EEG with generalized slow activity; Allergy
Astigmatism; Microphthalmia; Deeply set eye; Hypermetropia; Microcephaly; Trichiasis; Progeroid facial appearance; Anisometropia; Psychomotor retardation
Astigmatism; Motor delay; Delayed speech and language development; Joint hypermobility; Long fingers
Astigmatism; Velopharyngeal insufficiency; Inguinal hernia; Feeding difficulties; Vomiting; Umbilical hernia; Speech articulation difficulties; Ectopic thymus tissue; Abnormal soft palate morphology

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 1

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HGVS	dbSNP	gnomAD frequency
NM_001105539.3(ZBTB10):c.466C>T (p.Arg156Ter)	rs2131466699

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