List of variants reported as likely benign for immunodeficiency, common variable, 1 by Labcorp Genetics (formerly Invitae), Labcorp

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Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 136

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HGVS	dbSNP	gnomAD frequency
NM_012092.4(ICOS):c.451G>C (p.Val151Leu)	rs76778263	0.00226
NM_003809.3(TNFSF12):c.357G>A (p.Gln119=)	rs147826685	0.00113
NM_012092.4(ICOS):c.438A>T (p.Gly146=)	rs139449630	0.00014
NM_012092.4(ICOS):c.567C>G (p.Ala189=)	rs373368532	0.00014
NM_012092.4(ICOS):c.531C>T (p.Asn177=)	rs370645286	0.00011
NM_012092.4(ICOS):c.597A>G (p.Leu199=)	rs145698501	0.00011
NM_003809.3(TNFSF12):c.450C>T (p.Ile150=)	rs147597489	0.00009
NM_003809.3(TNFSF12):c.690C>G (p.Pro230=)	rs1237382978	0.00009
NM_012092.4(ICOS):c.93T>C (p.Phe31=)	rs147754976	0.00009
NM_003809.3(TNFSF12):c.729C>T (p.Phe243=)	rs200770110	0.00007
NM_003809.3(TNFSF12):c.374-9C>T	rs367612596	0.00006
NM_003809.3(TNFSF12):c.373+18G>A	rs370242260	0.00005
NM_003809.3(TNFSF12):c.374-8G>A	rs551460083	0.00004
NM_003809.3(TNFSF12):c.42G>A (p.Gly14=)	rs1170763703	0.00004
NM_003809.3(TNFSF12):c.159+15C>T	rs1274339400	0.00003
NM_012092.4(ICOS):c.42C>A (p.Arg14=)	rs765158675	0.00003
NM_012092.4(ICOS):c.510A>G (p.Ser170=)	rs148435889	0.00003
NM_003809.3(TNFSF12):c.141G>T (p.Arg47=)	rs1167726401	0.00002
NM_003809.3(TNFSF12):c.159+11G>T	rs1051286778	0.00002
NM_003809.3(TNFSF12):c.321C>T (p.Ile107=)	rs139642600	0.00002
NM_003809.3(TNFSF12):c.381C>T (p.Asp127=)	rs576803878	0.00002
NM_012092.4(ICOS):c.105C>T (p.Asn35=)	rs201031378	0.00002
NM_012092.4(ICOS):c.402A>G (p.Gln134=)	rs776847112	0.00002
NM_012092.4(ICOS):c.471A>G (p.Gly157=)	rs754099136	0.00002
NM_012092.4(ICOS):c.516T>C (p.Ser172=)	rs150573153	0.00002
NM_012092.4(ICOS):c.586+20T>G	rs750304925	0.00002
NM_012092.4(ICOS):c.9A>C (p.Ser3=)	rs1360705806	0.00002
NM_003809.3(TNFSF12):c.105C>G (p.Leu35=)	rs908438555	0.00001
NM_003809.3(TNFSF12):c.159+7C>A	rs535840017	0.00001
NM_003809.3(TNFSF12):c.208-7C>G	rs2070983662	0.00001
NM_003809.3(TNFSF12):c.318G>A (p.Ala106=)	rs764045774	0.00001
NM_003809.3(TNFSF12):c.337+12G>A	rs1367179093	0.00001
NM_003809.3(TNFSF12):c.337+14G>A	rs751618286	0.00001
NM_003809.3(TNFSF12):c.499-10C>T	rs1323154572	0.00001
NM_003809.3(TNFSF12):c.529C>T (p.Leu177=)	rs1239258225	0.00001
NM_003809.3(TNFSF12):c.663G>T (p.Gly221=)	rs776034989	0.00001
NM_012092.4(ICOS):c.163T>C (p.Leu55=)	rs1291412174	0.00001
NM_012092.4(ICOS):c.177G>A (p.Gly59=)	rs775111991	0.00001
NM_012092.4(ICOS):c.189C>T (p.Cys63=)	rs537195517	0.00001
NM_012092.4(ICOS):c.390T>A (p.Ile130=)	rs1257110059	0.00001
NM_012092.4(ICOS):c.411C>T (p.Cys137=)	rs1260496726	0.00001
NM_012092.4(ICOS):c.522C>T (p.His174=)	rs376555288	0.00001
NM_012092.4(ICOS):c.599A>G (p.Ter200=)	rs1196963607	0.00001
NM_003809.3(TNFSF12):c.105C>T (p.Leu35=)	rs908438555
NM_003809.3(TNFSF12):c.108C>T (p.Gly36=)	rs2150904074
NM_003809.3(TNFSF12):c.120C>T (p.Ala40=)
NM_003809.3(TNFSF12):c.147G>A (p.Ser49=)	rs1036232885
NM_003809.3(TNFSF12):c.159+7C>T	rs535840017
NM_003809.3(TNFSF12):c.160-14C>T
NM_003809.3(TNFSF12):c.160-16C>T
NM_003809.3(TNFSF12):c.160-21_160-17del
NM_003809.3(TNFSF12):c.186A>G (p.Ala62=)	rs2150904254
NM_003809.3(TNFSF12):c.207+10C>T
NM_003809.3(TNFSF12):c.207+11G>A	rs1266540123
NM_003809.3(TNFSF12):c.207+14G>A
NM_003809.3(TNFSF12):c.207+17G>A
NM_003809.3(TNFSF12):c.207+18C>T
NM_003809.3(TNFSF12):c.207+19G>A
NM_003809.3(TNFSF12):c.208-15C>T
NM_003809.3(TNFSF12):c.208-19C>G
NM_003809.3(TNFSF12):c.208-8T>A	rs2150904642
NM_003809.3(TNFSF12):c.219C>G (p.Pro73=)	rs2150904657
NM_003809.3(TNFSF12):c.243T>C (p.Pro81=)
NM_003809.3(TNFSF12):c.246G>A (p.Ala82=)
NM_003809.3(TNFSF12):c.249T>C (p.Pro83=)
NM_003809.3(TNFSF12):c.258C>T (p.Asn86=)
NM_003809.3(TNFSF12):c.288T>G (p.Pro96=)
NM_003809.3(TNFSF12):c.312A>G (p.Arg104=)	rs1326993093
NM_003809.3(TNFSF12):c.337+16G>A
NM_003809.3(TNFSF12):c.337+7G>A
NM_003809.3(TNFSF12):c.360C>T (p.Asp120=)
NM_003809.3(TNFSF12):c.366G>A (p.Ala122=)	rs529570679
NM_003809.3(TNFSF12):c.373+17C>T
NM_003809.3(TNFSF12):c.373+18G>T
NM_003809.3(TNFSF12):c.375T>G (p.Gly125=)
NM_003809.3(TNFSF12):c.384G>A (p.Gly128=)	rs1486694236
NM_003809.3(TNFSF12):c.393T>C (p.Ser131=)
NM_003809.3(TNFSF12):c.402G>A (p.Glu134=)
NM_003809.3(TNFSF12):c.417C>T (p.Asn139=)
NM_003809.3(TNFSF12):c.438C>T (p.Tyr146=)
NM_003809.3(TNFSF12):c.441C>T (p.Asn147=)	rs2150909109
NM_003809.3(TNFSF12):c.465C>T (p.Val155=)
NM_003809.3(TNFSF12):c.498+12C>G
NM_003809.3(TNFSF12):c.498+7C>T
NM_003809.3(TNFSF12):c.498+9del	rs1356188583
NM_003809.3(TNFSF12):c.499-4C>T	rs993444940
NM_003809.3(TNFSF12):c.51C>A (p.Gly17=)
NM_003809.3(TNFSF12):c.535C>T (p.Leu179=)	rs2150909482
NM_003809.3(TNFSF12):c.54C>T (p.Thr18=)
NM_003809.3(TNFSF12):c.573C>T (p.Cys191=)
NM_003809.3(TNFSF12):c.600G>A (p.Ala200=)
NM_003809.3(TNFSF12):c.609C>G (p.Leu203=)	rs140608168
NM_003809.3(TNFSF12):c.60G>C (p.Leu20=)
NM_003809.3(TNFSF12):c.60G>T (p.Leu20=)	rs898490512
NM_003809.3(TNFSF12):c.624C>A (p.Arg208=)
NM_003809.3(TNFSF12):c.651C>T (p.Ala217=)
NM_003809.3(TNFSF12):c.657G>A (p.Arg219=)
NM_003809.3(TNFSF12):c.657G>T (p.Arg219=)	rs1363429844
NM_003809.3(TNFSF12):c.673C>A (p.Arg225=)	rs761260715
NM_003809.3(TNFSF12):c.687C>T (p.Leu229=)
NM_003809.3(TNFSF12):c.69G>A (p.Pro23=)
NM_003809.3(TNFSF12):c.87C>T (p.Gly29=)
NM_003809.3(TNFSF12):c.90G>A (p.Leu30=)
NM_003809.3(TNFSF12):c.93G>A (p.Ala31=)
NM_003809.3(TNFSF12):c.96G>A (p.Leu32=)
NM_012092.4(ICOS):c.102C>T (p.His34=)
NM_012092.4(ICOS):c.186C>G (p.Leu62=)	rs1553499319
NM_012092.4(ICOS):c.186C>T (p.Leu62=)	rs1553499319
NM_012092.4(ICOS):c.249C>T (p.Cys83=)
NM_012092.4(ICOS):c.294C>T (p.Asn98=)	rs2105754276
NM_012092.4(ICOS):c.336A>G (p.Ser112=)	rs1335754145
NM_012092.4(ICOS):c.387T>C (p.His129=)
NM_012092.4(ICOS):c.394+14T>G
NM_012092.4(ICOS):c.394+17A>G
NM_012092.4(ICOS):c.394+19C>T
NM_012092.4(ICOS):c.394+7C>T	rs2105754340
NM_012092.4(ICOS):c.394+9T>C	rs1482892394
NM_012092.4(ICOS):c.395-15T>C	rs2105754735
NM_012092.4(ICOS):c.395-17del
NM_012092.4(ICOS):c.395-18C>A
NM_012092.4(ICOS):c.395-19A>G
NM_012092.4(ICOS):c.395-4C>A
NM_012092.4(ICOS):c.427T>C (p.Leu143=)
NM_012092.4(ICOS):c.501+12C>T
NM_012092.4(ICOS):c.501+16C>G
NM_012092.4(ICOS):c.525C>T (p.Asp175=)
NM_012092.4(ICOS):c.552A>G (p.Arg184=)	rs1471545594
NM_012092.4(ICOS):c.555A>G (p.Ala185=)
NM_012092.4(ICOS):c.576T>C (p.Ser192=)
NM_012092.4(ICOS):c.58+13T>C
NM_012092.4(ICOS):c.58+20T>G
NM_012092.4(ICOS):c.586+11A>G
NM_012092.4(ICOS):c.586+12T>C	rs2105755616
NM_012092.4(ICOS):c.59-16C>A	rs745431176
NM_012092.4(ICOS):c.59-7T>C
NM_012092.4(ICOS):c.595C>T (p.Leu199=)

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