ClinVar Miner

Variants studied for MUTYH-related attenuated familial adenomatous polyposis

Included ClinVar conditions (4):
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign not provided total
72 57 383 146 12 1 634

Gene and significance breakdown #

Total genes and gene combinations: 2
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Gene or gene combination pathogenic likely pathogenic uncertain significance likely benign benign not provided total
MUTYH 72 57 365 136 11 1 605
MUTYH, TOE1 0 0 18 10 1 0 29

Submitter and significance breakdown #

Total submitters: 22
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Submitter pathogenic likely pathogenic uncertain significance likely benign benign not provided total
Invitae 59 26 346 132 11 0 574
Counsyl 13 19 68 30 1 0 131
Mendelics 11 3 30 1 0 0 45
Illumina Clinical Services Laboratory,Illumina 6 3 23 1 1 0 34
Department of Pathology and Laboratory Medicine,Sinai Health System 20 3 0 0 0 0 23
Integrated Genetics/Laboratory Corporation of America 12 10 0 0 0 0 22
Fulgent Genetics 6 0 8 0 0 0 14
GeneReviews 11 0 0 0 0 0 11
Laboratory for Molecular Medicine,Partners HealthCare Personalized Medicine 7 0 0 0 0 0 7
OMIM 6 0 0 0 0 0 6
Center for Human Genetics, Inc 2 1 2 0 0 0 5
Biesecker Lab/Human Development Section,National Institutes of Health 2 2 0 0 0 0 4
Division of Genomic Diagnostics,The Children's Hospital of Philadelphia 1 0 1 1 1 0 4
Soonchunhyang University Bucheon Hospital,Soonchunhyang University Medical Center 1 1 2 0 0 0 4
Molecular Oncology Laboratory,Hospital Clínico San Carlos 1 1 1 0 0 0 3
CSER_CC_NCGL; University of Washington Medical Center 1 0 1 0 0 0 2
Division of Human Genetics,Children's Hospital of Philadelphia 1 1 0 0 0 0 2
Knight Diagnostic Laboratories,Oregon Health and Sciences University 1 1 0 0 0 0 2
University of Washington Department of Laboratory Medicine,University of Washington 0 1 0 1 0 0 2
Genomic Research Center,Shahid Beheshti University of Medical Sciences 1 0 0 0 0 0 1
Donald Williams Parsons Laboratory,Baylor College of Medicine 1 0 0 0 0 0 1
GenomeConnect, ClinGen 0 0 0 0 0 1 1

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