ClinVar Miner

List of variants in gene TYK2 reported as uncertain significance for immunodeficiency 35

Included ClinVar conditions (1):
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:
Total variants: 444
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HGVS dbSNP gnomAD frequency
NM_003331.5(TYK2):c.*120C>T rs556369340 0.00159
NM_003331.5(TYK2):c.1869C>T (p.Asp623=) rs140078545 0.00110
NM_003331.5(TYK2):c.2250C>T (p.Gly750=) rs138652649 0.00093
NM_003331.5(TYK2):c.193+14G>A rs199931972 0.00041
NM_003331.5(TYK2):c.2453G>A (p.Arg818His) rs145437969 0.00039
NM_003331.5(TYK2):c.2985C>T (p.Ile995=) rs147442318 0.00031
NM_003331.5(TYK2):c.648G>A (p.Pro216=) rs142642403 0.00030
NM_003331.5(TYK2):c.1141C>T (p.Arg381Trp) rs201240289 0.00027
NM_003331.5(TYK2):c.2670G>C (p.Thr890=) rs144332908 0.00026
NM_003331.5(TYK2):c.2017G>T (p.Val673Leu) rs528691386 0.00021
NM_003331.5(TYK2):c.1486G>A (p.Gly496Ser) rs202072909 0.00020
NM_003331.5(TYK2):c.1238C>T (p.Ala413Val) rs138661716 0.00019
NM_003331.5(TYK2):c.1807G>A (p.Val603Met) rs140594440 0.00019
NM_003331.5(TYK2):c.211T>C (p.Phe71Leu) rs374071090 0.00019
NM_003331.5(TYK2):c.3011C>G (p.Ala1004Gly) rs202110875 0.00019
NM_003331.5(TYK2):c.*174G>A rs534835524 0.00016
NM_003331.5(TYK2):c.2102G>C (p.Arg701Thr) rs200791116 0.00014
NM_003331.5(TYK2):c.466-3C>T rs375238658 0.00014
NM_003331.5(TYK2):c.-145C>T rs778404429 0.00013
NM_003331.5(TYK2):c.1669+4C>T rs377283741 0.00013
NM_003331.5(TYK2):c.630-3C>T rs750663278 0.00013
NM_003331.5(TYK2):c.821G>A (p.Arg274His) rs371937276 0.00013
NM_003331.5(TYK2):c.1094C>T (p.Pro365Leu) rs373929549 0.00012
NM_003331.5(TYK2):c.-322C>T rs548281602 0.00011
NM_003331.5(TYK2):c.-79C>G rs921883780 0.00011
NM_003331.5(TYK2):c.1954G>A (p.Ala652Thr) rs144290894 0.00011
NM_003331.5(TYK2):c.589C>T (p.Arg197Cys) rs376427383 0.00011
NM_003331.5(TYK2):c.1559G>A (p.Gly520Asp) rs142576987 0.00010
NM_003331.5(TYK2):c.1806C>T (p.Asn602=) rs765576893 0.00010
NM_003331.5(TYK2):c.1398C>T (p.Pro466=) rs200752112 0.00009
NM_003331.5(TYK2):c.1646G>A (p.Arg549His) rs536181491 0.00009
NM_003331.5(TYK2):c.2441C>T (p.Pro814Leu) rs143743593 0.00009
NM_003331.5(TYK2):c.2494C>T (p.Arg832Trp) rs144995884 0.00009
NM_003331.5(TYK2):c.727C>T (p.Arg243Trp) rs200003143 0.00009
NM_003331.5(TYK2):c.794G>A (p.Arg265Gln) rs775315394 0.00009
NM_003331.5(TYK2):c.1342C>T (p.Arg448Trp) rs147991080 0.00008
NM_003331.5(TYK2):c.2003C>T (p.Thr668Met) rs146430107 0.00008
NM_003331.5(TYK2):c.2429A>T (p.Asp810Val) rs371070470 0.00008
NM_003331.5(TYK2):c.3560G>A (p.Cys1187Tyr) rs200932305 0.00008
NM_003331.5(TYK2):c.36T>G (p.Ser12Arg) rs769741671 0.00008
NM_003331.5(TYK2):c.372T>C (p.Arg124=) rs371832787 0.00008
NM_003331.5(TYK2):c.449A>G (p.Glu150Gly) rs200718118 0.00008
NM_003331.5(TYK2):c.489C>T (p.Asp163=) rs748475805 0.00008
NM_003331.5(TYK2):c.783C>G (p.Ala261=) rs371939297 0.00008
NM_003331.5(TYK2):c.1621G>A (p.Gly541Arg) rs768654573 0.00007
NM_003331.5(TYK2):c.1711C>T (p.Pro571Ser) rs867249402 0.00007
NM_003331.5(TYK2):c.2035C>T (p.Arg679Cys) rs368828208 0.00007
NM_003331.5(TYK2):c.937A>G (p.Thr313Ala) rs954391030 0.00007
NM_003331.5(TYK2):c.1055T>C (p.Phe352Ser) rs778243582 0.00006
NM_003331.5(TYK2):c.1156G>A (p.Val386Met) rs55956017 0.00006
NM_003331.5(TYK2):c.118G>A (p.Gly40Arg) rs763286803 0.00006
NM_003331.5(TYK2):c.1273C>T (p.Arg425Cys) rs777227495 0.00006
NM_003331.5(TYK2):c.1282G>A (p.Ala428Thr) rs754798989 0.00006
NM_003331.5(TYK2):c.1508G>A (p.Arg503Gln) rs541104349 0.00006
NM_003331.5(TYK2):c.2176-9C>T rs370673325 0.00006
NM_003331.5(TYK2):c.2315G>A (p.Arg772Gln) rs148823525 0.00006
NM_003331.5(TYK2):c.2350C>G (p.Leu784Val) rs759014184 0.00006
NM_003331.5(TYK2):c.329G>A (p.Arg110Gln) rs56090991 0.00006
NM_003331.5(TYK2):c.493G>A (p.Ala165Thr) rs370420133 0.00006
NM_003331.5(TYK2):c.649C>T (p.Arg217Cys) rs754414161 0.00006
NM_003331.5(TYK2):c.662G>A (p.Arg221Gln) rs747608147 0.00006
NM_003331.5(TYK2):c.*173C>T rs766203641 0.00005
NM_003331.5(TYK2):c.-37C>T rs1166754820 0.00005
NM_003331.5(TYK2):c.10C>T (p.Arg4Cys) rs368801193 0.00005
NM_003331.5(TYK2):c.1235C>T (p.Ala412Val) rs371919786 0.00005
NM_003331.5(TYK2):c.1394G>A (p.Arg465Gln) rs771922681 0.00005
NM_003331.5(TYK2):c.1585C>T (p.Leu529Phe) rs375614264 0.00005
NM_003331.5(TYK2):c.1691T>G (p.Met564Arg) rs72561470 0.00005
NM_003331.5(TYK2):c.1851G>A (p.Glu617=) rs780346579 0.00005
NM_003331.5(TYK2):c.2038G>A (p.Gly680Ser) rs745582179 0.00005
NM_003331.5(TYK2):c.2099G>A (p.Arg700Gln) rs149540700 0.00005
NM_003331.5(TYK2):c.232G>A (p.Asp78Asn) rs778171865 0.00005
NM_003331.5(TYK2):c.2359G>A (p.Gly787Arg) rs267605272 0.00005
NM_003331.5(TYK2):c.2687A>G (p.Tyr896Cys) rs372017111 0.00005
NM_003331.5(TYK2):c.3487G>A (p.Glu1163Lys) rs529855217 0.00005
NM_003331.4(TYK2):c.*302C>T rs886054131 0.00004
NM_003331.5(TYK2):c.1229G>A (p.Arg410Gln) rs755169274 0.00004
NM_003331.5(TYK2):c.1254G>A (p.Ser418=) rs201945206 0.00004
NM_003331.5(TYK2):c.1393C>T (p.Arg465Trp) rs371207387 0.00004
NM_003331.5(TYK2):c.1469G>A (p.Arg490His) rs369615833 0.00004
NM_003331.5(TYK2):c.1501C>T (p.Arg501Trp) rs756944840 0.00004
NM_003331.5(TYK2):c.1502G>A (p.Arg501Gln) rs200643906 0.00004
NM_003331.5(TYK2):c.1839C>T (p.Ser613=) rs748006603 0.00004
NM_003331.5(TYK2):c.1968C>T (p.Tyr656=) rs764154157 0.00004
NM_003331.5(TYK2):c.2648A>G (p.Asp883Gly) rs750627511 0.00004
NM_003331.5(TYK2):c.3239A>G (p.Tyr1080Cys) rs776034616 0.00004
NM_003331.5(TYK2):c.349C>T (p.Pro117Ser) rs141864691 0.00004
NM_003331.5(TYK2):c.517G>A (p.Glu173Lys) rs56222823 0.00004
NM_003331.5(TYK2):c.703C>T (p.Arg235Trp) rs767776173 0.00004
NM_003331.5(TYK2):c.704G>A (p.Arg235Gln) rs907669947 0.00004
NM_003331.5(TYK2):c.*260C>T rs1258476690 0.00003
NM_003331.5(TYK2):c.1576G>A (p.Val526Ile) rs758682935 0.00003
NM_003331.5(TYK2):c.1643G>A (p.Arg548His) rs746253617 0.00003
NM_003331.5(TYK2):c.1705G>A (p.Ala569Thr) rs760031894 0.00003
NM_003331.5(TYK2):c.1820G>A (p.Arg607His) rs759137101 0.00003
NM_003331.5(TYK2):c.1898G>A (p.Arg633His) rs769794516 0.00003
NM_003331.5(TYK2):c.2026G>A (p.Val676Ile) rs868590753 0.00003
NM_003331.5(TYK2):c.2404G>A (p.Ala802Thr) rs148148659 0.00003
NM_003331.5(TYK2):c.2456G>A (p.Ser819Asn) rs763006605 0.00003
NM_003331.5(TYK2):c.2495G>A (p.Arg832Gln) rs376161606 0.00003
NM_003331.5(TYK2):c.256C>A (p.Pro86Thr) rs141466711 0.00003
NM_003331.5(TYK2):c.2646G>C (p.Pro882=) rs184567726 0.00003
NM_003331.5(TYK2):c.2896T>G (p.Cys966Gly) rs763754692 0.00003
NM_003331.5(TYK2):c.359C>T (p.Pro120Leu) rs758463317 0.00003
NM_003331.5(TYK2):c.437C>T (p.Pro146Leu) rs137904701 0.00003
NM_003331.5(TYK2):c.505G>A (p.Glu169Lys) rs778545468 0.00003
NM_003331.5(TYK2):c.64A>G (p.Met22Val) rs777395821 0.00003
NM_003331.5(TYK2):c.670C>T (p.Arg224Trp) rs920085264 0.00003
NM_003331.5(TYK2):c.691C>T (p.Arg231Trp) rs201917359 0.00003
NM_003331.5(TYK2):c.793C>T (p.Arg265Trp) rs760177831 0.00003
NM_003331.5(TYK2):c.820C>T (p.Arg274Cys) rs748218971 0.00003
NM_003331.5(TYK2):c.1228C>T (p.Arg410Trp) rs780993314 0.00002
NM_003331.5(TYK2):c.1325G>A (p.Arg442Gln) rs2304254 0.00002
NM_003331.5(TYK2):c.1399G>A (p.Glu467Lys) rs779259245 0.00002
NM_003331.5(TYK2):c.1627G>A (p.Asp543Asn) rs747616008 0.00002
NM_003331.5(TYK2):c.2011G>A (p.Ala671Thr) rs1247499935 0.00002
NM_003331.5(TYK2):c.2077G>A (p.Gly693Arg) rs754899482 0.00002
NM_003331.5(TYK2):c.2197G>A (p.Gly733Ser) rs1038590632 0.00002
NM_003331.5(TYK2):c.2314C>T (p.Arg772Trp) rs755089851 0.00002
NM_003331.5(TYK2):c.2370C>T (p.Ser790=) rs762732975 0.00002
NM_003331.5(TYK2):c.2452C>T (p.Arg818Cys) rs751075108 0.00002
NM_003331.5(TYK2):c.248T>C (p.Val83Ala) rs1407281800 0.00002
NM_003331.5(TYK2):c.2506C>T (p.Pro836Ser) rs1169822550 0.00002
NM_003331.5(TYK2):c.2653C>A (p.Pro885Thr) rs377212879 0.00002
NM_003331.5(TYK2):c.277A>T (p.Ile93Phe) rs1434718123 0.00002
NM_003331.5(TYK2):c.2974C>T (p.Arg992Trp) rs370401636 0.00002
NM_003331.5(TYK2):c.3201-15C>T rs766488790 0.00002
NM_003331.5(TYK2):c.3326T>G (p.Leu1109Arg) rs753179617 0.00002
NM_003331.5(TYK2):c.3385G>C (p.Glu1129Gln) rs746144391 0.00002
NM_003331.5(TYK2):c.353G>A (p.Arg118Gln) rs369530676 0.00002
NM_003331.5(TYK2):c.3555C>T (p.Ser1185=) rs372903125 0.00002
NM_003331.5(TYK2):c.525G>C (p.Glu175Asp) rs780262705 0.00002
NM_003331.5(TYK2):c.580C>T (p.Leu194Phe) rs373574074 0.00002
NM_003331.5(TYK2):c.658C>T (p.Arg220Cys) rs557436288 0.00002
NM_003331.5(TYK2):c.697C>T (p.Arg233Cys) rs1296148213 0.00002
NM_003331.5(TYK2):c.698G>A (p.Arg233His) rs753240259 0.00002
NM_003331.5(TYK2):c.740C>T (p.Pro247Leu) rs746989305 0.00002
NM_003331.5(TYK2):c.932C>T (p.Pro311Leu) rs1191624543 0.00002
NM_003331.5(TYK2):c.*291T>C rs537387706 0.00001
NM_003331.5(TYK2):c.1106C>T (p.Pro369Leu) rs760895143 0.00001
NM_003331.5(TYK2):c.1142G>A (p.Arg381Gln) rs1038910642 0.00001
NM_003331.5(TYK2):c.1207C>G (p.Leu403Val) rs774318353 0.00001
NM_003331.5(TYK2):c.1249G>A (p.Val417Met) rs776878637 0.00001
NM_003331.5(TYK2):c.125C>T (p.Pro42Leu) rs761736148 0.00001
NM_003331.5(TYK2):c.1274G>A (p.Arg425His) rs150601734 0.00001
NM_003331.5(TYK2):c.1280C>T (p.Thr427Met) rs748061804 0.00001
NM_003331.5(TYK2):c.1292G>A (p.Ser431Asn) rs1270833514 0.00001
NM_003331.5(TYK2):c.1297T>C (p.Tyr433His) rs764428779 0.00001
NM_003331.5(TYK2):c.1324C>T (p.Arg442Trp) rs762546704 0.00001
NM_003331.5(TYK2):c.1404C>T (p.Asp468=) rs374132564 0.00001
NM_003331.5(TYK2):c.1433G>T (p.Ser478Ile) rs141250995 0.00001
NM_003331.5(TYK2):c.1444C>T (p.Arg482Cys) rs146770568 0.00001
NM_003331.5(TYK2):c.1466A>G (p.Gln489Arg) rs1349507320 0.00001
NM_003331.5(TYK2):c.149C>T (p.Ser50Leu) rs747484809 0.00001
NM_003331.5(TYK2):c.1543G>A (p.Val515Met) rs769911839 0.00001
NM_003331.5(TYK2):c.1579C>T (p.Arg527Trp) rs777266572 0.00001
NM_003331.5(TYK2):c.1580G>A (p.Arg527Gln) rs755791270 0.00001
NM_003331.5(TYK2):c.1642C>T (p.Arg548Cys) rs772532784 0.00001
NM_003331.5(TYK2):c.179T>C (p.Ile60Thr) rs752152984 0.00001
NM_003331.5(TYK2):c.1819C>T (p.Arg607Cys) rs151252201 0.00001
NM_003331.5(TYK2):c.1826G>A (p.Arg609Gln) rs748626480 0.00001
NM_003331.5(TYK2):c.1877C>A (p.Pro626His) rs764378445 0.00001
NM_003331.5(TYK2):c.187A>G (p.Lys63Glu) rs1249291887 0.00001
NM_003331.5(TYK2):c.1882G>A (p.Val628Met) rs972695864 0.00001
NM_003331.5(TYK2):c.1887T>A (p.Pro629=) rs773984009 0.00001
NM_003331.5(TYK2):c.1913G>A (p.Arg638Gln) rs780399902 0.00001
NM_003331.5(TYK2):c.200C>G (p.Thr67Ser) rs774905892 0.00001
NM_003331.5(TYK2):c.2041C>T (p.Pro681Ser) rs1433952909 0.00001
NM_003331.5(TYK2):c.2068G>A (p.Val690Met) rs752724238 0.00001
NM_003331.5(TYK2):c.2108G>A (p.Arg703Gln) rs552478414 0.00001
NM_003331.5(TYK2):c.2124G>A (p.Met708Ile) rs201502911 0.00001
NM_003331.5(TYK2):c.2204T>C (p.Val735Ala) rs754086085 0.00001
NM_003331.5(TYK2):c.2306G>A (p.Arg769Lys) rs1322975760 0.00001
NM_003331.5(TYK2):c.2353C>T (p.Pro785Ser) rs972911609 0.00001
NM_003331.5(TYK2):c.2360G>A (p.Gly787Glu) rs1323264570 0.00001
NM_003331.5(TYK2):c.2435A>G (p.Glu812Gly) rs528324154 0.00001
NM_003331.5(TYK2):c.2528C>T (p.Thr843Ile) rs914166364 0.00001
NM_003331.5(TYK2):c.2602C>T (p.Arg868Trp) rs762311335 0.00001
NM_003331.5(TYK2):c.2603G>A (p.Arg868Gln) rs776925265 0.00001
NM_003331.5(TYK2):c.2629G>A (p.Val877Ile) rs146540753 0.00001
NM_003331.5(TYK2):c.2645C>T (p.Pro882Leu) rs1140385 0.00001
NM_003331.5(TYK2):c.2658G>A (p.Ala886=) rs761205319 0.00001
NM_003331.5(TYK2):c.2716-3C>T rs745696767 0.00001
NM_003331.5(TYK2):c.2902G>T (p.Asp968Tyr) rs1438500444 0.00001
NM_003331.5(TYK2):c.2908+4G>A rs766865578 0.00001
NM_003331.5(TYK2):c.2935G>A (p.Glu979Lys) rs531721749 0.00001
NM_003331.5(TYK2):c.2966A>G (p.Tyr989Cys) rs765912261 0.00001
NM_003331.5(TYK2):c.2983A>G (p.Ile995Val) rs764232789 0.00001
NM_003331.5(TYK2):c.3076G>A (p.Ala1026Thr) rs771434577 0.00001
NM_003331.5(TYK2):c.311G>A (p.Arg104His) rs774448680 0.00001
NM_003331.5(TYK2):c.317+4G>T rs777758037 0.00001
NM_003331.5(TYK2):c.3191C>G (p.Pro1064Arg) rs1300605416 0.00001
NM_003331.5(TYK2):c.328C>T (p.Arg110Trp) rs747918278 0.00001
NM_003331.5(TYK2):c.3307A>G (p.Ser1103Gly) rs750525541 0.00001
NM_003331.5(TYK2):c.3349G>T (p.Gly1117Cys) rs1568324534 0.00001
NM_003331.5(TYK2):c.3407G>A (p.Arg1136Gln) rs756742784 0.00001
NM_003331.5(TYK2):c.3418T>A (p.Cys1140Ser) rs751899914 0.00001
NM_003331.5(TYK2):c.3481A>G (p.Thr1161Ala) rs905890917 0.00001
NM_003331.5(TYK2):c.3525G>A (p.Lys1175=) rs377283866 0.00001
NM_003331.5(TYK2):c.3556G>A (p.Val1186Met) rs754920273 0.00001
NM_003331.5(TYK2):c.370C>T (p.Arg124Cys) rs757581005 0.00001
NM_003331.5(TYK2):c.406C>A (p.Gln136Lys) rs766052825 0.00001
NM_003331.5(TYK2):c.602C>T (p.Pro201Leu) rs752615354 0.00001
NM_003331.5(TYK2):c.650G>A (p.Arg217His) rs373143912 0.00001
NM_003331.5(TYK2):c.661C>T (p.Arg221Trp) rs200858844 0.00001
NM_003331.5(TYK2):c.735C>G (p.Phe245Leu) rs1454450816 0.00001
NM_003331.5(TYK2):c.806G>A (p.Arg269His) rs770841701 0.00001
NM_003331.5(TYK2):c.829G>A (p.Val277Met) rs148520054 0.00001
NM_003331.5(TYK2):c.859G>A (p.Glu287Lys) rs1415920933 0.00001
NM_003331.5(TYK2):c.879C>T (p.Ile293=) rs375414145 0.00001
NM_003331.5(TYK2):c.970A>G (p.Ile324Val) rs1443990878 0.00001
NC_000019.10:g.(?_10350814)_(10351182_?)dup
NC_000019.10:g.(?_10378194)_(10378426_?)dup
NC_000019.9:g.(?_10461510)_(10461858_?)dup
NC_000019.9:g.(?_10488870)_(10489082_?)dup
NM_003331.5(TYK2):c.*261C>A rs1313565853
NM_003331.5(TYK2):c.*63G>A rs185435731
NM_003331.5(TYK2):c.-154A>G rs2042302135
NM_003331.5(TYK2):c.-23C>T rs886054135
NM_003331.5(TYK2):c.-328T>G rs886054136
NM_003331.5(TYK2):c.-369C>T rs886054137
NM_003331.5(TYK2):c.-9G>A rs2042248932
NM_003331.5(TYK2):c.1000A>G (p.Asn334Asp) rs886054133
NM_003331.5(TYK2):c.1003_1005del (p.Lys335del)
NM_003331.5(TYK2):c.1011+12G>A rs377517686
NM_003331.5(TYK2):c.1011+3G>A rs1373705538
NM_003331.5(TYK2):c.1019G>A (p.Ser340Asn) rs1599350449
NM_003331.5(TYK2):c.1022G>T (p.Gly341Val)
NM_003331.5(TYK2):c.1045G>A (p.Ala349Thr)
NM_003331.5(TYK2):c.1081G>T (p.Ala361Ser)
NM_003331.5(TYK2):c.1082C>T (p.Ala361Val) rs373246540
NM_003331.5(TYK2):c.1151C>G (p.Thr384Ser) rs2145243198
NM_003331.5(TYK2):c.1189C>T (p.Arg397Trp)
NM_003331.5(TYK2):c.11G>A (p.Arg4His) rs12720343
NM_003331.5(TYK2):c.11G>C (p.Arg4Pro) rs12720343
NM_003331.5(TYK2):c.1200C>G (p.Asn400Lys) rs2041581409
NM_003331.5(TYK2):c.1209+18G>A
NM_003331.5(TYK2):c.1226C>T (p.Ser409Phe)
NM_003331.5(TYK2):c.124C>A (p.Pro42Thr) rs147251502
NM_003331.5(TYK2):c.124C>G (p.Pro42Ala) rs147251502
NM_003331.5(TYK2):c.1255C>G (p.Leu419Val) rs1236600614
NM_003331.5(TYK2):c.1322C>G (p.Pro441Arg) rs770604675
NM_003331.5(TYK2):c.1375T>C (p.Phe459Leu) rs1599346193
NM_003331.5(TYK2):c.1388A>G (p.Lys463Arg) rs1338265886
NM_003331.5(TYK2):c.1415T>A (p.Leu472His)
NM_003331.5(TYK2):c.1459G>A (p.Val487Met) rs202083880
NM_003331.5(TYK2):c.1489A>C (p.Met497Leu) rs751952281
NM_003331.5(TYK2):c.1531G>T (p.Asp511Tyr) rs1568334900
NM_003331.5(TYK2):c.1534G>C (p.Gly512Arg) rs146786766
NM_003331.5(TYK2):c.1535G>A (p.Gly512Glu) rs2041453734
NM_003331.5(TYK2):c.1561C>G (p.Arg521Gly)
NM_003331.5(TYK2):c.1562G>C (p.Arg521Pro)
NM_003331.5(TYK2):c.1571C>G (p.Pro524Arg)
NM_003331.5(TYK2):c.1579C>G (p.Arg527Gly) rs777266572
NM_003331.5(TYK2):c.1643G>T (p.Arg548Leu) rs746253617
NM_003331.5(TYK2):c.1645C>T (p.Arg549Cys)
NM_003331.5(TYK2):c.1653C>G (p.Cys551Trp) rs1456271893
NM_003331.5(TYK2):c.1663C>T (p.Pro555Ser) rs887962195
NM_003331.5(TYK2):c.1669+12G>A rs2041444641
NM_003331.5(TYK2):c.1669+7_1669+8inv
NM_003331.5(TYK2):c.1670-3C>G rs2041441123
NM_003331.5(TYK2):c.1678A>C (p.Asn560His) rs758279947
NM_003331.5(TYK2):c.1683CAT[2] (p.Ile563del) rs754148696
NM_003331.5(TYK2):c.1699G>A (p.Ala567Thr) rs1314158344
NM_003331.5(TYK2):c.16T>A (p.Trp6Arg) rs533026972
NM_003331.5(TYK2):c.16T>G (p.Trp6Gly)
NM_003331.5(TYK2):c.1747C>T (p.Arg583Trp)
NM_003331.5(TYK2):c.1748G>A (p.Arg583Gln) rs771605702
NM_003331.5(TYK2):c.1762G>A (p.Glu588Lys)
NM_003331.5(TYK2):c.1767C>G (p.Ile589Met)
NM_003331.5(TYK2):c.1787G>C (p.Gly596Ala)
NM_003331.5(TYK2):c.1805A>G (p.Asn602Ser)
NM_003331.5(TYK2):c.1841G>A (p.Gly614Glu) rs2041422669
NM_003331.5(TYK2):c.1881C>T (p.Leu627=)
NM_003331.5(TYK2):c.1897C>T (p.Arg633Cys)
NM_003331.5(TYK2):c.1898G>T (p.Arg633Leu)
NM_003331.5(TYK2):c.1913G>T (p.Arg638Leu) rs780399902
NM_003331.5(TYK2):c.1919T>C (p.Val640Ala) rs2145214611
NM_003331.5(TYK2):c.1925A>G (p.Lys642Arg) rs745986684
NM_003331.5(TYK2):c.193+5G>C rs2145370839
NM_003331.5(TYK2):c.1936C>T (p.Pro646Ser)
NM_003331.5(TYK2):c.1960-11G>A
NM_003331.5(TYK2):c.1960-12C>A
NM_003331.5(TYK2):c.1978A>G (p.Ser660Gly) rs975547596
NM_003331.5(TYK2):c.2017G>A (p.Val673Met) rs528691386
NM_003331.5(TYK2):c.2023G>A (p.Gly675Ser) rs2041401700
NM_003331.5(TYK2):c.202C>G (p.Pro68Ala) rs1045396233
NM_003331.5(TYK2):c.2032G>A (p.Val678Met) rs1568333725
NM_003331.5(TYK2):c.2033T>C (p.Val678Ala) rs1555718506
NM_003331.5(TYK2):c.2036G>A (p.Arg679His) rs200247986
NM_003331.5(TYK2):c.2036G>C (p.Arg679Pro) rs200247986
NM_003331.5(TYK2):c.2044_2045delinsAT (p.Glu682Ile)
NM_003331.5(TYK2):c.2077G>C (p.Gly693Arg)
NM_003331.5(TYK2):c.2138T>G (p.Val713Gly) rs749003655
NM_003331.5(TYK2):c.2167A>G (p.Ser723Gly)
NM_003331.5(TYK2):c.2171A>C (p.Tyr724Ser) rs549371062
NM_003331.5(TYK2):c.2176-3C>T rs2145187614
NM_003331.5(TYK2):c.2177A>T (p.Glu726Val)
NM_003331.5(TYK2):c.2188C>G (p.Leu730Val) rs1316426026
NM_003331.5(TYK2):c.2213G>A (p.Arg738Gln)
NM_003331.5(TYK2):c.2218A>G (p.Ile740Val) rs2041195057
NM_003331.5(TYK2):c.2228C>T (p.Ala743Val)
NM_003331.5(TYK2):c.2230C>T (p.Arg744Trp) rs142676100
NM_003331.5(TYK2):c.2231G>A (p.Arg744Gln)
NM_003331.5(TYK2):c.2273G>C (p.Ser758Thr) rs774929306
NM_003331.5(TYK2):c.2293G>A (p.Gly765Ser) rs1197074529
NM_003331.5(TYK2):c.2300T>C (p.Leu767Pro)
NM_003331.5(TYK2):c.232G>T (p.Asp78Tyr) rs778171865
NM_003331.5(TYK2):c.2339C>T (p.Ala780Val) rs1357157419
NM_003331.5(TYK2):c.2344G>A (p.Glu782Lys) rs2145185225
NM_003331.5(TYK2):c.2357G>A (p.Gly786Asp)
NM_003331.5(TYK2):c.2371_2376del (p.Leu791_Ser792del) rs773966828
NM_003331.5(TYK2):c.2380G>A (p.Ala794Thr) rs748433361
NM_003331.5(TYK2):c.2383A>G (p.Met795Val)
NM_003331.5(TYK2):c.2437G>T (p.Ala813Ser) rs752386163
NM_003331.5(TYK2):c.2448G>C (p.Gln816His)
NM_003331.5(TYK2):c.2450G>A (p.Ser817Asn)
NM_003331.5(TYK2):c.2458C>A (p.Pro820Thr) rs1220172517
NM_003331.5(TYK2):c.2467-6C>T
NM_003331.5(TYK2):c.2500C>T (p.Pro834Ser) rs748485968
NM_003331.5(TYK2):c.2503G>C (p.Glu835Gln) rs757987854
NM_003331.5(TYK2):c.2515C>G (p.Pro839Ala)
NM_003331.5(TYK2):c.2534C>T (p.Thr845Ile) rs1209330159
NM_003331.5(TYK2):c.2558C>G (p.Pro853Arg) rs551747806
NM_003331.5(TYK2):c.2569C>T (p.Pro857Ser)
NM_003331.5(TYK2):c.260C>T (p.Pro87Leu) rs2145275752
NM_003331.5(TYK2):c.2616C>G (p.His872Gln) rs745552967
NM_003331.5(TYK2):c.2618-10A>G
NM_003331.5(TYK2):c.2618-14C>G rs532521303
NM_003331.5(TYK2):c.262A>G (p.Asn88Asp)
NM_003331.5(TYK2):c.2644C>G (p.Pro882Ala)
NM_003331.5(TYK2):c.2657C>A (p.Ala886Glu) rs764682808
NM_003331.5(TYK2):c.2657C>T (p.Ala886Val)
NM_003331.5(TYK2):c.2660C>G (p.Ser887Trp) rs776000744
NM_003331.5(TYK2):c.2664C>A (p.Asp888Glu) rs201456217
NM_003331.5(TYK2):c.2664C>G (p.Asp888Glu)
NM_003331.5(TYK2):c.2707C>G (p.Leu903Val)
NM_003331.5(TYK2):c.2715+9C>T rs886054132
NM_003331.5(TYK2):c.2716-13C>A rs370899700
NM_003331.5(TYK2):c.2740T>C (p.Tyr914His)
NM_003331.5(TYK2):c.276G>C (p.Glu92Asp)
NM_003331.5(TYK2):c.2778G>A (p.Met926Ile) rs963707334
NM_003331.5(TYK2):c.2792C>T (p.Ala931Val) rs56255228
NM_003331.5(TYK2):c.2812C>G (p.Pro938Ala) rs1489073249
NM_003331.5(TYK2):c.281C>G (p.Pro94Arg) rs765557425
NM_003331.5(TYK2):c.2821C>G (p.Arg941Gly) rs2040960541
NM_003331.5(TYK2):c.2821C>T (p.Arg941Cys)
NM_003331.5(TYK2):c.2843T>C (p.Ile948Thr)
NM_003331.5(TYK2):c.284G>A (p.Arg95Lys) rs1599355965
NM_003331.5(TYK2):c.286G>T (p.Asp96Tyr) rs2145275479
NM_003331.5(TYK2):c.2885A>G (p.Tyr962Cys) rs758656059
NM_003331.5(TYK2):c.2900A>G (p.Glu967Gly) rs2036762184
NM_003331.5(TYK2):c.2917T>G (p.Ser973Ala) rs2040927992
NM_003331.5(TYK2):c.2942T>C (p.Val981Ala)
NM_003331.5(TYK2):c.2953A>T (p.Ser985Cys) rs2145149687
NM_003331.5(TYK2):c.2957T>C (p.Leu986Pro)
NM_003331.5(TYK2):c.2979C>G (p.His993Gln)
NM_003331.5(TYK2):c.2981G>A (p.Ser994Asn)
NM_003331.5(TYK2):c.2986G>C (p.Gly996Arg) rs772177678
NM_003331.5(TYK2):c.3013CAG[1] (p.Gln1006del)
NM_003331.5(TYK2):c.3070C>A (p.Leu1024Ile) rs566658678
NM_003331.5(TYK2):c.3096C>A (p.Asp1032Glu) rs763514629
NM_003331.5(TYK2):c.3149A>C (p.Glu1050Ala) rs1568326297
NM_003331.5(TYK2):c.316A>C (p.Arg106=) rs2145275203
NM_003331.5(TYK2):c.3178G>C (p.Asp1060His) rs2040886709
NM_003331.5(TYK2):c.318G>A (p.Arg106=)
NM_003331.5(TYK2):c.3200+11G>A rs2040885202
NM_003331.5(TYK2):c.3200+13G>T rs2145143773
NM_003331.5(TYK2):c.3200+5C>T rs2040885783
NM_003331.5(TYK2):c.3215G>T (p.Cys1072Phe)
NM_003331.5(TYK2):c.3227A>G (p.Tyr1076Cys)
NM_003331.5(TYK2):c.3236A>G (p.Tyr1079Cys) rs2040862596
NM_003331.5(TYK2):c.3242C>G (p.Ala1081Gly) rs2040862056
NM_003331.5(TYK2):c.3290A>G (p.His1097Arg)
NM_003331.5(TYK2):c.3308G>C (p.Ser1103Thr)
NM_003331.5(TYK2):c.3313C>G (p.Pro1105Ala)
NM_003331.5(TYK2):c.3318+5G>A
NM_003331.5(TYK2):c.3318+6A>T rs2040857696
NM_003331.5(TYK2):c.3318G>T (p.Thr1106=)
NM_003331.5(TYK2):c.3325C>T (p.Leu1109Phe) rs2145127143
NM_003331.5(TYK2):c.3331C>T (p.Leu1111Phe)
NM_003331.5(TYK2):c.333C>G (p.Asn111Lys) rs2041753647
NM_003331.5(TYK2):c.3359C>G (p.Thr1120Arg) rs768580902
NM_003331.5(TYK2):c.3384G>A (p.Leu1128=)
NM_003331.5(TYK2):c.3386A>G (p.Glu1129Gly) rs1298150782
NM_003331.5(TYK2):c.3388C>G (p.Arg1130Gly) rs779037308
NM_003331.5(TYK2):c.3389G>A (p.Arg1130Gln)
NM_003331.5(TYK2):c.3475C>A (p.Arg1159Ser) rs753470142
NM_003331.5(TYK2):c.3486C>A (p.Phe1162Leu)
NM_003331.5(TYK2):c.34A>G (p.Ser12Gly) rs2042247201
NM_003331.5(TYK2):c.3520G>A (p.Glu1174Lys) rs1469065798
NM_003331.5(TYK2):c.352C>T (p.Arg118Trp)
NM_003331.5(TYK2):c.3532G>A (p.Gly1178Ser) rs747542256
NM_003331.5(TYK2):c.3539C>T (p.Ala1180Val)
NM_003331.5(TYK2):c.3542C>T (p.Pro1181Leu) rs1233179704
NM_003331.5(TYK2):c.3544T>C (p.Ser1182Pro) rs1311022826
NM_003331.5(TYK2):c.373T>C (p.Cys125Arg) rs2145273513
NM_003331.5(TYK2):c.386_391del (p.Gly129_Thr130del) rs1555720565
NM_003331.5(TYK2):c.422T>C (p.Met141Thr)
NM_003331.5(TYK2):c.43G>A (p.Val15Ile) rs374780145
NM_003331.5(TYK2):c.43G>T (p.Val15Phe) rs374780145
NM_003331.5(TYK2):c.490G>A (p.Val164Met) rs531355933
NM_003331.5(TYK2):c.490G>T (p.Val164Leu) rs531355933
NM_003331.5(TYK2):c.498A>G (p.Ser166=) rs969593614
NM_003331.5(TYK2):c.517GAG[2] (p.Glu175del) rs1297227067
NM_003331.5(TYK2):c.553G>A (p.Gly185Ser)
NM_003331.5(TYK2):c.55G>A (p.Ala19Thr) rs755381338
NM_003331.5(TYK2):c.572T>C (p.Leu191Pro) rs2145258740
NM_003331.5(TYK2):c.583G>A (p.Ala195Thr) rs201107041
NM_003331.5(TYK2):c.583G>T (p.Ala195Ser) rs201107041
NM_003331.5(TYK2):c.589C>G (p.Arg197Gly)
NM_003331.5(TYK2):c.59A>C (p.Gln20Pro)
NM_003331.5(TYK2):c.647C>T (p.Pro216Leu)
NM_003331.5(TYK2):c.653C>G (p.Ser218Cys)
NM_003331.5(TYK2):c.655T>C (p.Phe219Leu)
NM_003331.5(TYK2):c.659G>A (p.Arg220His)
NM_003331.5(TYK2):c.675G>T (p.Gln225His)
NM_003331.5(TYK2):c.692G>A (p.Arg231Gln) rs761141309
NM_003331.5(TYK2):c.692G>C (p.Arg231Pro) rs761141309
NM_003331.5(TYK2):c.709G>T (p.Val237Phe) rs369423520
NM_003331.5(TYK2):c.716G>A (p.Arg239His)
NM_003331.5(TYK2):c.728G>A (p.Arg243Gln) rs577896346
NM_003331.5(TYK2):c.737A>G (p.Gln246Arg) rs886054134
NM_003331.5(TYK2):c.739C>T (p.Pro247Ser) rs2145252429
NM_003331.5(TYK2):c.740C>A (p.Pro247Gln)
NM_003331.5(TYK2):c.749T>C (p.Leu250Pro) rs2145252243
NM_003331.5(TYK2):c.762G>A (p.Met254Ile)
NM_003331.5(TYK2):c.766A>G (p.Met256Val)
NM_003331.5(TYK2):c.789C>T (p.Leu263=)
NM_003331.5(TYK2):c.809T>C (p.Phe270Ser) rs1599351746
NM_003331.5(TYK2):c.80G>A (p.Gly27Asp) rs753473919
NM_003331.5(TYK2):c.80G>T (p.Gly27Val)
NM_003331.5(TYK2):c.829G>T (p.Val277Leu)
NM_003331.5(TYK2):c.835C>A (p.His279Asn) rs2041627608
NM_003331.5(TYK2):c.850G>A (p.Ala284Thr) rs1599351623
NM_003331.5(TYK2):c.859G>C (p.Glu287Gln) rs1415920933
NM_003331.5(TYK2):c.861G>T (p.Glu287Asp) rs760138236
NM_003331.5(TYK2):c.871T>C (p.Cys291Arg)
NM_003331.5(TYK2):c.880C>T (p.Arg294Trp)
NM_003331.5(TYK2):c.881G>A (p.Arg294Gln)
NM_003331.5(TYK2):c.935C>T (p.Pro312Leu) rs1354965673
NM_003331.5(TYK2):c.938C>T (p.Thr313Ile) rs2145250076
NM_003331.5(TYK2):c.975G>T (p.Gln325His) rs762767796
NM_003331.5(TYK2):c.985G>A (p.Val329Ile) rs759288032

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