List of variants reported as uncertain significance for Lynch syndrome 4 by Mendelics

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Total variants: 27

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HGVS	dbSNP	gnomAD frequency
NM_000535.7(PMS2):c.2523G>A (p.Trp841Ter)	rs587780057	0.00174
NM_000535.7(PMS2):c.572A>G (p.Tyr191Cys)	rs375289386	0.00029
NM_000535.7(PMS2):c.953A>G (p.Tyr318Cys)	rs139438201	0.00022
NM_000535.7(PMS2):c.2012C>T (p.Thr671Met)	rs587780046	0.00017
NM_000535.7(PMS2):c.1555T>C (p.Tyr519His)	rs370236216	0.00011
NM_000535.7(PMS2):c.1490G>A (p.Gly497Asp)	rs199739859	0.00008
NM_000535.7(PMS2):c.1432A>G (p.Ser478Gly)	rs144389038	0.00005
NM_000535.7(PMS2):c.1211C>G (p.Pro404Arg)	rs536111818	0.00004
NM_000535.7(PMS2):c.2347G>A (p.Val783Ile)	rs553286217	0.00004
NM_000535.7(PMS2):c.113C>T (p.Ala38Val)	rs148270248	0.00002
NM_000535.7(PMS2):c.2062A>G (p.Ile688Val)	rs1060503144	0.00001
NM_000535.7(PMS2):c.825A>T (p.Gln275His)	rs876659736	0.00001
NM_000535.7(PMS2):c.881G>A (p.Arg294Gln)	rs373239341	0.00001
NM_000535.7(PMS2):c.1180A>G (p.Lys394Glu)	rs1583323711
NM_000535.7(PMS2):c.1219A>G (p.Arg407Gly)	rs776725795
NM_000535.7(PMS2):c.1354G>C (p.Gly452Arg)	rs569947936
NM_000535.7(PMS2):c.1473G>C (p.Glu491Asp)	rs530105089
NM_000535.7(PMS2):c.1534G>A (p.Gly512Ser)	rs1060503127
NM_000535.7(PMS2):c.1564A>G (p.Ser522Gly)	rs1554297553
NM_000535.7(PMS2):c.1633T>C (p.Ser545Pro)	rs1247571278
NM_000535.7(PMS2):c.1700A>G (p.Gln567Arg)	rs112104877
NM_000535.7(PMS2):c.1759A>C (p.Ser587Arg)	rs1554297277
NM_000535.7(PMS2):c.2186_2187del (p.Leu729fs)	rs587779335
NM_000535.7(PMS2):c.439A>C (p.Thr147Pro)	rs1583403496
NM_000535.7(PMS2):c.446A>C (p.Tyr149Ser)	rs1554304003
NM_000535.7(PMS2):c.708G>T (p.Leu236Phe)	rs201395630
NM_000535.7(PMS2):c.948C>A (p.His316Gln)	rs1219573982

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