ClinVar Miner

List of variants reported as uncertain significance for 3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndrome by Invitae

Included ClinVar conditions (1):
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ClinVar version:
Total variants: 105
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HGVS dbSNP gnomAD frequency
NM_032861.4(SERAC1):c.1404-3C>G rs367596327 0.00045
NM_032861.4(SERAC1):c.1259T>C (p.Ile420Thr) rs114741005 0.00036
NM_032861.4(SERAC1):c.1660T>G (p.Leu554Val) rs149034301 0.00036
NM_032861.4(SERAC1):c.91A>G (p.Arg31Gly) rs146896149 0.00034
NM_032861.4(SERAC1):c.1688C>G (p.Ser563Cys) rs146410859 0.00024
NM_032861.4(SERAC1):c.1483A>C (p.Ile495Leu) rs370591885 0.00014
NM_032861.4(SERAC1):c.1538C>T (p.Thr513Met) rs143065058 0.00014
NM_032861.4(SERAC1):c.391T>C (p.Cys131Arg) rs147085187 0.00013
NM_032861.4(SERAC1):c.583C>T (p.Pro195Ser) rs546374310 0.00009
NM_032861.4(SERAC1):c.418A>G (p.Ser140Gly) rs370340688 0.00008
NM_032861.4(SERAC1):c.1084A>T (p.Ile362Phe) rs537530231 0.00006
NM_032861.4(SERAC1):c.1640G>A (p.Arg547His) rs756639108 0.00004
NM_032861.4(SERAC1):c.1763del (p.Val588fs) rs770661156 0.00004
NM_032861.4(SERAC1):c.413G>A (p.Arg138Gln) rs863224200 0.00004
NM_032861.4(SERAC1):c.524C>T (p.Pro175Leu) rs536508664 0.00004
NM_032861.4(SERAC1):c.553G>A (p.Glu185Lys) rs543967244 0.00004
NM_032861.4(SERAC1):c.674A>G (p.Glu225Gly) rs375757326 0.00004
NM_032861.4(SERAC1):c.69T>G (p.Ser23Arg) rs754908475 0.00004
NM_032861.4(SERAC1):c.855A>G (p.Ile285Met) rs745441822 0.00004
NM_032861.4(SERAC1):c.1292C>T (p.Thr431Met) rs779852958 0.00003
NM_032861.4(SERAC1):c.329C>T (p.Ala110Val) rs368403843 0.00003
NM_032861.4(SERAC1):c.1270A>G (p.Met424Val) rs367903368 0.00002
NM_032861.4(SERAC1):c.1642T>C (p.Tyr548His) rs1331741437 0.00002
NM_032861.4(SERAC1):c.1846C>A (p.Leu616Ile) rs780572089 0.00002
NM_032861.4(SERAC1):c.487+5T>C rs748641688 0.00002
NM_032861.4(SERAC1):c.932G>T (p.Cys311Phe) rs1449129513 0.00002
NM_032861.4(SERAC1):c.1169A>G (p.Gln390Arg) rs779061767 0.00001
NM_032861.4(SERAC1):c.1295C>T (p.Thr432Met) rs780982964 0.00001
NM_032861.4(SERAC1):c.1403+5C>G rs770722498 0.00001
NM_032861.4(SERAC1):c.1501+6T>G rs760987565 0.00001
NM_032861.4(SERAC1):c.1535C>T (p.Ser512Phe) rs751450632 0.00001
NM_032861.4(SERAC1):c.1537A>G (p.Thr513Ala) rs201367107 0.00001
NM_032861.4(SERAC1):c.1685-3C>T rs367733861 0.00001
NM_032861.4(SERAC1):c.1725_1727dup (p.Glu575_Phe576insLeu) rs1478893955 0.00001
NM_032861.4(SERAC1):c.1762G>A (p.Val588Met) rs756012789 0.00001
NM_032861.4(SERAC1):c.1765G>A (p.Glu589Lys) rs1020569740 0.00001
NM_032861.4(SERAC1):c.1915C>T (p.Arg639Cys) rs575982148 0.00001
NM_032861.4(SERAC1):c.326C>T (p.Ser109Leu) rs1258024323 0.00001
NM_032861.4(SERAC1):c.677G>T (p.Cys226Phe) rs1243289662 0.00001
NM_032861.4(SERAC1):c.87T>G (p.Asp29Glu) rs1404505029 0.00001
NM_032861.4(SERAC1):c.1003A>G (p.Ile335Val)
NM_032861.4(SERAC1):c.1009C>T (p.Arg337Cys)
NM_032861.4(SERAC1):c.1166G>A (p.Ser389Asn)
NM_032861.4(SERAC1):c.118C>T (p.Leu40Phe)
NM_032861.4(SERAC1):c.1195A>G (p.Ile399Val)
NM_032861.4(SERAC1):c.1203C>A (p.Gly401=)
NM_032861.4(SERAC1):c.1272G>A (p.Met424Ile)
NM_032861.4(SERAC1):c.1308+6G>A
NM_032861.4(SERAC1):c.1334C>A (p.Ala445Asp) rs553879407
NM_032861.4(SERAC1):c.1364C>G (p.Thr455Ser) rs767870142
NM_032861.4(SERAC1):c.1365C>T (p.Thr455=)
NM_032861.4(SERAC1):c.1374C>T (p.Ser458=)
NM_032861.4(SERAC1):c.1375G>A (p.Asp459Asn) rs189064007
NM_032861.4(SERAC1):c.1396A>G (p.Met466Val)
NM_032861.4(SERAC1):c.1491T>A (p.His497Gln) rs1064796860
NM_032861.4(SERAC1):c.1501+4A>C rs755406082
NM_032861.4(SERAC1):c.1501+4A>G rs755406082
NM_032861.4(SERAC1):c.1501+5G>A
NM_032861.4(SERAC1):c.1505T>G (p.Leu502Arg) rs2128410682
NM_032861.4(SERAC1):c.1519_1521dup (p.Met507_Leu508insMet)
NM_032861.4(SERAC1):c.152A>G (p.Glu51Gly)
NM_032861.4(SERAC1):c.1628C>T (p.Ser543Phe)
NM_032861.4(SERAC1):c.1720C>G (p.Leu574Val)
NM_032861.4(SERAC1):c.1766A>C (p.Glu589Ala)
NM_032861.4(SERAC1):c.1793T>C (p.Met598Thr)
NM_032861.4(SERAC1):c.1825G>A (p.Ala609Thr)
NM_032861.4(SERAC1):c.1829-6C>G
NM_032861.4(SERAC1):c.1839T>A (p.Ile613=)
NM_032861.4(SERAC1):c.1916G>A (p.Arg639His) rs768913919
NM_032861.4(SERAC1):c.1916G>C (p.Arg639Pro) rs768913919
NM_032861.4(SERAC1):c.1926_1930del (p.Gln642fs)
NM_032861.4(SERAC1):c.1934G>A (p.Arg645His)
NM_032861.4(SERAC1):c.194T>C (p.Val65Ala)
NM_032861.4(SERAC1):c.1962C>G (p.Asn654Lys) rs1784140439
NM_032861.4(SERAC1):c.1963_*1del (p.Ter655SerextTer?)
NM_032861.4(SERAC1):c.1965A>G (p.Ter655=)
NM_032861.4(SERAC1):c.203G>A (p.Arg68Gln) rs1384614641
NM_032861.4(SERAC1):c.206A>G (p.Glu69Gly) rs2128422343
NM_032861.4(SERAC1):c.21C>G (p.Cys7Trp) rs139301835
NM_032861.4(SERAC1):c.254G>A (p.Gly85Glu) rs376468988
NM_032861.4(SERAC1):c.301G>A (p.Ala101Thr)
NM_032861.4(SERAC1):c.340C>T (p.Arg114Trp)
NM_032861.4(SERAC1):c.341G>A (p.Arg114Gln)
NM_032861.4(SERAC1):c.412C>T (p.Arg138Trp)
NM_032861.4(SERAC1):c.429T>A (p.Asp143Glu)
NM_032861.4(SERAC1):c.44G>A (p.Gly15Glu) rs1785406112
NM_032861.4(SERAC1):c.458G>A (p.Arg153Gln)
NM_032861.4(SERAC1):c.488-3T>G rs2128420377
NM_032861.4(SERAC1):c.536T>C (p.Ile179Thr)
NM_032861.4(SERAC1):c.566T>C (p.Leu189Pro)
NM_032861.4(SERAC1):c.566T>G (p.Leu189Arg) rs576602246
NM_032861.4(SERAC1):c.568C>T (p.Arg190Cys) rs564717592
NM_032861.4(SERAC1):c.719A>G (p.Gln240Arg)
NM_032861.4(SERAC1):c.734A>G (p.Gln245Arg)
NM_032861.4(SERAC1):c.738+5G>C
NM_032861.4(SERAC1):c.772C>T (p.Pro258Ser) rs571113650
NM_032861.4(SERAC1):c.808A>G (p.Thr270Ala)
NM_032861.4(SERAC1):c.819G>A (p.Met273Ile)
NM_032861.4(SERAC1):c.821T>C (p.Phe274Ser)
NM_032861.4(SERAC1):c.863A>C (p.His288Pro)
NM_032861.4(SERAC1):c.86A>G (p.Asp29Gly) rs779737059
NM_032861.4(SERAC1):c.871A>G (p.Lys291Glu)
NM_032861.4(SERAC1):c.931T>C (p.Cys311Arg) rs2128415147
NM_032861.4(SERAC1):c.940G>T (p.Val314Leu)
NM_032861.4(SERAC1):c.958C>T (p.Arg320Cys)

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