List of variants reported as uncertain significance for T-B- severe combined immunodeficiency by Center for Genomics, Ann and Robert H. Lurie Children's Hospital of Chicago

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Total variants: 27

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HGVS	dbSNP	gnomAD frequency
NM_000022.4(ADA):c.425G>A (p.Arg142Gln)	rs61732239	0.00399
NM_206937.2(LIG4):c.2525C>A (p.Ala842Asp)	rs72660870	0.00129
NM_005356.5(LCK):c.601G>A (p.Gly201Ser)	rs11567841	0.00121
NM_006904.7(PRKDC):c.6901C>G (p.Gln2301Glu)	rs376211703	0.00048
NM_001033855.3(DCLRE1C):c.1733A>G (p.Tyr578Cys)	rs778823769	0.00033
NM_206937.2(LIG4):c.712A>G (p.Ile238Val)	rs149012859	0.00019
NM_000536.4(RAG2):c.367C>T (p.Arg123Cys)	rs147319483	0.00016
NM_006904.7(PRKDC):c.3898A>G (p.Ser1300Gly)	rs368949953	0.00016
NM_006904.7(PRKDC):c.5572-4G>A	rs367584015	0.00016
NM_000536.4(RAG2):c.909G>T (p.Glu303Asp)	rs141025671	0.00012
NM_005356.5(LCK):c.1292C>T (p.Thr431Met)	rs1801124	0.00010
NM_006904.7(PRKDC):c.5107A>G (p.Thr1703Ala)	rs376188635	0.00009
NM_000022.4(ADA):c.831G>T (p.Glu277Asp)	rs542229902	0.00002
NM_000448.3(RAG1):c.1981_1983del (p.Met661del)	rs774103837	0.00002
NM_001033855.3(DCLRE1C):c.1709T>G (p.Ile570Ser)	rs769187936	0.00002
NM_006904.7(PRKDC):c.1713C>T (p.Ser571=)	rs373088662	0.00002
NM_006904.7(PRKDC):c.4138G>A (p.Ala1380Thr)	rs56209904	0.00002
NM_000448.3(RAG1):c.549G>A (p.Met183Ile)	rs750394886	0.00001
NM_006904.7(PRKDC):c.11561C>T (p.Ala3854Val)	rs779943187	0.00001
NM_006904.7(PRKDC):c.7812G>A (p.Pro2604=)	rs763035246	0.00001
NM_024782.3(NHEJ1):c.825+3G>A	rs750458375	0.00001
NM_206937.2(LIG4):c.1242A>C (p.Val414=)	rs150828164	0.00001
NM_001033855.3(DCLRE1C):c.1556C>T (p.Pro519Leu)	rs542791233
NM_001033855.3(DCLRE1C):c.1903dup (p.Ser635fs)	rs760288938
NM_001033855.3(DCLRE1C):c.678+5G>A	rs750695358
NM_006904.7(PRKDC):c.3236C>T (p.Ser1079Leu)
NM_206937.2(LIG4):c.2356G>A (p.Glu786Lys)	rs200756045

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