List of variants reported as benign for congenital hypothyroidism by Diagnostic Laboratory, Department of Genetics, University Medical Center Groningen

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Total variants: 23

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HGVS	dbSNP	gnomAD frequency
NM_001363711.2(DUOX2):c.3515+15T>A	rs269869	0.99253
NM_000549.5(TSHB):c.40A>G (p.Thr14Ala)	rs10776792	0.97659
NM_001555.5(IGSF1):c.948G>A (p.Val316=)	rs5932877	0.91610
NM_203395.3(IYD):c.687+1305T>C	rs612421	0.91223
NM_207581.4(DUOXA2):c.298C>G (p.Arg100Gly)	rs2576090	0.86315
NM_207581.4(DUOXA2):c.554+6T>C	rs2576092	0.77669
NM_001363711.2(DUOX2):c.413C>T (p.Pro138Leu)	rs2001616	0.75375
NM_001363711.2(DUOX2):c.3200C>T (p.Ser1067Leu)	rs269868	0.71631
NM_207581.4(DUOXA2):c.555-18C>T	rs955152	0.69516
NM_207581.4(DUOXA2):c.341-15C>T	rs2252371	0.69439
NM_001206744.2(TPO):c.1193G>C (p.Ser398Thr)	rs2175977	0.65696
NM_001206744.2(TPO):c.2540T>C (p.Val847Ala)	rs1126799	0.62508
NM_001555.5(IGSF1):c.1347A>G (p.Glu449=)	rs1128617	0.48301
NM_001206744.2(TPO):c.2173A>C (p.Thr725Pro)	rs732609	0.46998
NM_001206744.2(TPO):c.1117G>T (p.Ala373Ser)	rs2280132	0.43513
NM_001206744.2(TPO):c.2145C>T (p.Pro715=)	rs732608	0.41037
NM_001555.5(IGSF1):c.2556T>C (p.Tyr852=)	rs4830219	0.36154
NM_001206744.2(TPO):c.1998C>T (p.Asp666=)	rs1126797	0.35994
NM_000453.3(SLC5A5):c.1652-9G>A	rs4808708	0.18985
NM_001206744.2(TPO):c.12C>G (p.Leu4=)	rs9678281
NM_001206744.2(TPO):c.769G>T (p.Ala257Ser)	rs4927611
NM_001363711.2(DUOX2):c.1461G>C (p.Gly487=)	rs269860
NM_207581.4(DUOXA2):c.341-4A>G	rs2554459

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