List of variants in gene TP53 studied for acute myeloid leukemia

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
		ClinVar version:

Total variants: 98

Download table as spreadsheet

HGVS	dbSNP	gnomAD frequency
NM_000546.6(TP53):c.215C>G (p.Pro72Arg)	rs1042522	0.62654
NM_000546.6(TP53):c.743G>A (p.Arg248Gln)	rs11540652	0.00002
NM_000546.6(TP53):c.374C>T (p.Thr125Met)	rs786201057	0.00001
NM_000546.6(TP53):c.535C>T (p.His179Tyr)	rs587780070	0.00001
NM_000546.6(TP53):c.536A>G (p.His179Arg)	rs1057519991	0.00001
NM_000546.6(TP53):c.578A>C (p.His193Pro)	rs786201838	0.00001
NM_000546.6(TP53):c.659A>G (p.Tyr220Cys)	rs121912666	0.00001
NM_000546.6(TP53):c.817C>T (p.Arg273Cys)	rs121913343	0.00001
NM_000546.6(TP53):c.824G>A (p.Cys275Tyr)	rs863224451	0.00001
NM_000546.6(TP53):c.-29+4907G>T
NM_000546.6(TP53):c.-29+4908G>C
NM_000546.6(TP53):c.-29+4914G>T
NM_000546.6(TP53):c.-29+4915del
NM_000546.6(TP53):c.-29+4952G>C
NM_000546.6(TP53):c.-29+5027A>T
NM_000546.6(TP53):c.-29+5029A>G
NM_000546.6(TP53):c.-29+5139C>A
NM_000546.6(TP53):c.323_329dup (p.Leu111fs)	rs1131691004
NM_000546.6(TP53):c.331del (p.Leu111fs)	rs2151039122
NM_000546.6(TP53):c.373A>C (p.Thr125Pro)	rs1057520003
NM_000546.6(TP53):c.374C>A (p.Thr125Lys)	rs786201057
NM_000546.6(TP53):c.374C>G (p.Thr125Arg)	rs786201057
NM_000546.6(TP53):c.421T>A (p.Cys141Ser)	rs1057519978
NM_000546.6(TP53):c.421T>C (p.Cys141Arg)	rs1057519978
NM_000546.6(TP53):c.421T>G (p.Cys141Gly)	rs1057519978
NM_000546.6(TP53):c.422G>A (p.Cys141Tyr)	rs587781288
NM_000546.6(TP53):c.422G>T (p.Cys141Phe)	rs587781288
NM_000546.6(TP53):c.423C>G (p.Cys141Trp)	rs1057519977
NM_000546.6(TP53):c.449C>T (p.Thr150Ile)	rs2151032692
NM_000546.6(TP53):c.494A>T (p.Gln165Leu)
NM_000546.6(TP53):c.513G>T (p.Glu171Asp)
NM_000546.6(TP53):c.518T>C (p.Val173Ala)	rs1057519747
NM_000546.6(TP53):c.518T>G (p.Val173Gly)	rs1057519747
NM_000546.6(TP53):c.526T>A (p.Cys176Ser)	rs967461896
NM_000546.6(TP53):c.526T>C (p.Cys176Arg)	rs967461896
NM_000546.6(TP53):c.526T>G (p.Cys176Gly)	rs967461896
NM_000546.6(TP53):c.527G>A (p.Cys176Tyr)	rs786202962
NM_000546.6(TP53):c.527G>T (p.Cys176Phe)	rs786202962
NM_000546.6(TP53):c.528C>G (p.Cys176Trp)	rs1057519980
NM_000546.6(TP53):c.535C>A (p.His179Asn)	rs587780070
NM_000546.6(TP53):c.535C>G (p.His179Asp)	rs587780070
NM_000546.6(TP53):c.536A>C (p.His179Pro)	rs1057519991
NM_000546.6(TP53):c.536A>T (p.His179Leu)	rs1057519991
NM_000546.6(TP53):c.537T>A (p.His179Gln)	rs876660821
NM_000546.6(TP53):c.537T>G (p.His179Gln)	rs876660821
NM_000546.6(TP53):c.549A>T (p.Ser183=)
NM_000546.6(TP53):c.576del (p.Gln192fs)
NM_000546.6(TP53):c.577C>A (p.His193Asn)	rs876658468
NM_000546.6(TP53):c.577C>G (p.His193Asp)	rs876658468
NM_000546.6(TP53):c.577C>T (p.His193Tyr)	rs876658468
NM_000546.6(TP53):c.578A>G (p.His193Arg)	rs786201838
NM_000546.6(TP53):c.578A>T (p.His193Leu)	rs786201838
NM_000546.6(TP53):c.583A>T (p.Ile195Phe)	rs942158624
NM_000546.6(TP53):c.584T>A (p.Ile195Asn)	rs760043106
NM_000546.6(TP53):c.584T>C (p.Ile195Thr)	rs760043106
NM_000546.6(TP53):c.584T>G (p.Ile195Ser)	rs760043106
NM_000546.6(TP53):c.585C>G (p.Ile195Met)	rs1057519994
NM_000546.6(TP53):c.636del (p.Arg213fs)	rs864309495
NM_000546.6(TP53):c.643A>G (p.Ser215Gly)	rs886039484
NM_000546.6(TP53):c.644G>A (p.Ser215Asn)	rs587782177
NM_000546.6(TP53):c.644G>T (p.Ser215Ile)	rs587782177
NM_000546.6(TP53):c.645T>G (p.Ser215Arg)	rs1057520001
NM_000546.6(TP53):c.710T>A (p.Met237Lys)	rs765848205
NM_000546.6(TP53):c.719G>A (p.Ser240Asn)
NM_000546.6(TP53):c.742C>G (p.Arg248Gly)	rs121912651
NM_000546.6(TP53):c.742C>T (p.Arg248Trp)	rs121912651
NM_000546.6(TP53):c.743G>C (p.Arg248Pro)	rs11540652
NM_000546.6(TP53):c.743G>T (p.Arg248Leu)	rs11540652
NM_000546.6(TP53):c.745A>T (p.Arg249Trp)	rs587782082
NM_000546.6(TP53):c.746G>C (p.Arg249Thr)	rs587782329
NM_000546.6(TP53):c.752T>A (p.Ile251Asn)	rs730882027
NM_000546.6(TP53):c.761T>C (p.Ile254Thr)
NM_000546.6(TP53):c.800G>C (p.Arg267Pro)	rs587780075
NM_000546.6(TP53):c.801G>C (p.Arg267=)
NM_000546.6(TP53):c.805A>T (p.Ser269Cys)
NM_000546.6(TP53):c.806G>T (p.Ser269Ile)
NM_000546.6(TP53):c.817C>A (p.Arg273Ser)	rs121913343
NM_000546.6(TP53):c.818G>A (p.Arg273His)	rs28934576
NM_000546.6(TP53):c.818G>C (p.Arg273Pro)	rs28934576
NM_000546.6(TP53):c.818G>T (p.Arg273Leu)	rs28934576
NM_000546.6(TP53):c.838A>G (p.Arg280Gly)	rs753660142
NM_000546.6(TP53):c.839G>A (p.Arg280Lys)	rs121912660
NM_000546.6(TP53):c.839G>C (p.Arg280Thr)	rs121912660
NM_000546.6(TP53):c.839G>T (p.Arg280Ile)	rs121912660
NM_000546.6(TP53):c.856G>A (p.Glu286Lys)	rs786201059
NM_000546.6(TP53):c.856G>C (p.Glu286Gln)	rs786201059
NM_000546.6(TP53):c.857A>C (p.Glu286Ala)	rs1057519985
NM_000546.6(TP53):c.857A>G (p.Glu286Gly)	rs1057519985
NM_000546.6(TP53):c.857A>T (p.Glu286Val)	rs1057519985
NM_000546.6(TP53):c.952C>T (p.Pro318Ser)
NM_000546.6(TP53):c.954A>T (p.Pro318=)
NM_000546.6(TP53):c.969G>C (p.Leu323=)
NM_000546.6(TP53):c.970G>A (p.Asp324Asn)
NM_000546.6(TP53):c.977A>T (p.Glu326Val)
NM_000546.6(TP53):c.978A>G (p.Glu326=)
NM_000546.6(TP53):c.993+13G>A	rs369599972
NM_000546.6(TP53):c.993+44C>A
NM_000546.6(TP53):c.993+86del

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.