List of variants in gene RIT1 reported as likely benign for Noonan syndrome

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 104

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HGVS	dbSNP	gnomAD frequency
NM_006912.6(RIT1):c.237+10C>A	rs367785615	0.00014
NM_006912.6(RIT1):c.106+15C>T	rs755316223	0.00006
NM_006912.6(RIT1):c.231T>C (p.Ala77=)	rs144170253	0.00004
NM_006912.6(RIT1):c.291C>A (p.Ile97=)	rs377326705	0.00004
NM_006912.6(RIT1):c.-43-74G>A	rs730881012	0.00003
NM_006912.6(RIT1):c.45C>G (p.Pro15=)	rs748838734	0.00003
NM_006912.6(RIT1):c.465A>G (p.Glu155=)	rs2527171604	0.00003
NM_006912.6(RIT1):c.498A>C (p.Ala166=)	rs375734733	0.00003
NM_006912.6(RIT1):c.156C>T (p.Pro52=)	rs1571999270	0.00002
NM_006912.6(RIT1):c.430-16C>T	rs1160848351	0.00002
NM_006912.6(RIT1):c.106+10A>G	rs781557110	0.00001
NM_006912.6(RIT1):c.107-12C>T	rs2527197428	0.00001
NM_006912.6(RIT1):c.107-9C>G	rs200597833	0.00001
NM_006912.6(RIT1):c.108C>T (p.Ala36=)	rs962881455	0.00001
NM_006912.6(RIT1):c.120G>A (p.Gln40=)	rs1015730634	0.00001
NM_006912.6(RIT1):c.141A>G (p.Pro47=)	rs1057524417	0.00001
NM_006912.6(RIT1):c.163+12C>A	rs372092063	0.00001
NM_006912.6(RIT1):c.164-11C>T	rs960250196	0.00001
NM_006912.6(RIT1):c.18C>T (p.Arg6=)	rs1376159930	0.00001
NM_006912.6(RIT1):c.201G>A (p.Glu67=)	rs1254003235	0.00001
NM_006912.6(RIT1):c.237+11C>A	rs775926859	0.00001
NM_006912.6(RIT1):c.237+14G>C	rs772575179	0.00001
NM_006912.6(RIT1):c.237+18G>A	rs1344958293	0.00001
NM_006912.6(RIT1):c.237+19T>A	rs746073428	0.00001
NM_006912.6(RIT1):c.238-12G>C	rs999740208	0.00001
NM_006912.6(RIT1):c.238-19G>A	rs753538357	0.00001
NM_006912.6(RIT1):c.252C>T (p.Ala84=)	rs758393035	0.00001
NM_006912.6(RIT1):c.258G>A (p.Arg86=)	rs909585898	0.00001
NM_006912.6(RIT1):c.264G>A (p.Gln88=)	rs774818471	0.00001
NM_006912.6(RIT1):c.366A>G (p.Arg122=)	rs755664065	0.00001
NM_006912.6(RIT1):c.381A>C (p.Thr127=)	rs1206873288	0.00001
NM_006912.6(RIT1):c.393T>C (p.Leu131=)	rs34974790	0.00001
NM_006912.6(RIT1):c.408A>G (p.Ser136=)	rs766640740	0.00001
NM_006912.6(RIT1):c.421C>T (p.Leu141=)	rs931615845	0.00001
NM_006912.6(RIT1):c.423A>G (p.Leu141=)	rs763445246	0.00001
NM_006912.6(RIT1):c.429+15G>A	rs1404087606	0.00001
NM_006912.6(RIT1):c.430-18C>T	rs777450446	0.00001
NM_006912.6(RIT1):c.441A>G (p.Glu147=)	rs778896290	0.00001
NM_006912.6(RIT1):c.510T>C (p.Tyr170=)	rs765624804	0.00001
NM_006912.6(RIT1):c.516T>C (p.Asp172=)	rs148764677	0.00001
NM_006912.6(RIT1):c.540G>A (p.Arg180=)	rs369738767	0.00001
NM_006912.6(RIT1):c.564G>A (p.Glu188=)	rs1157330685	0.00001
NM_006912.6(RIT1):c.594G>A (p.Lys198=)	rs779457410	0.00001
NM_006912.6(RIT1):c.603C>T (p.Asn201=)	rs367886540	0.00001
NM_006912.6(RIT1):c.651A>G (p.Ser217=)	rs762892205	0.00001
NM_006912.6(RIT1):c.99G>A (p.Gly33=)	rs199914900	0.00001
NM_006912.6(RIT1):c.106+16C>T
NM_006912.6(RIT1):c.107-13_107-10del	rs750688522
NM_006912.6(RIT1):c.107-6T>G	rs2527197409
NM_006912.6(RIT1):c.107-9C>A	rs200597833
NM_006912.6(RIT1):c.131A>T (p.His44Leu)	rs2527197303
NM_006912.6(RIT1):c.156C>A (p.Pro52=)
NM_006912.6(RIT1):c.159C>T (p.Thr53=)
NM_006912.6(RIT1):c.163+10A>G	rs758651076
NM_006912.6(RIT1):c.163+12C>T	rs372092063
NM_006912.6(RIT1):c.163+16A>C	rs2527197178
NM_006912.6(RIT1):c.163+16_163+18dup
NM_006912.6(RIT1):c.163+17C>G	rs201898950
NM_006912.6(RIT1):c.163+17C>T
NM_006912.6(RIT1):c.164-10C>T
NM_006912.6(RIT1):c.164-18C>G	rs2102585269
NM_006912.6(RIT1):c.164-27_164-17dup	rs2527182513
NM_006912.6(RIT1):c.164-5T>C	rs2527182456
NM_006912.6(RIT1):c.164-6C>T
NM_006912.6(RIT1):c.237+12del	rs763868802
NM_006912.6(RIT1):c.237+9T>C	rs2527182174
NM_006912.6(RIT1):c.238-16C>T	rs763494925
NM_006912.6(RIT1):c.238-9T>A	rs2527180701
NM_006912.6(RIT1):c.246T>C (p.Phe82=)
NM_006912.6(RIT1):c.261C>T (p.Asp87=)	rs983862584
NM_006912.6(RIT1):c.273G>A (p.Arg91=)	rs2527180518
NM_006912.6(RIT1):c.285G>A (p.Gly95=)
NM_006912.6(RIT1):c.309G>C (p.Thr103=)	rs370396152
NM_006912.6(RIT1):c.313C>T (p.Arg105Cys)	rs2527180386
NM_006912.6(RIT1):c.316C>A (p.Arg106=)	rs779947152
NM_006912.6(RIT1):c.321T>C (p.Ser107=)	rs2102584781
NM_006912.6(RIT1):c.33C>T (p.Cys11=)
NM_006912.6(RIT1):c.351T>C (p.Leu117=)	rs2527180200
NM_006912.6(RIT1):c.381A>G (p.Thr127=)	rs1206873288
NM_006912.6(RIT1):c.384T>C (p.Pro128=)	rs2527179996
NM_006912.6(RIT1):c.387G>A (p.Val129=)	rs2527179983
NM_006912.6(RIT1):c.429+20T>C	rs2102584651
NM_006912.6(RIT1):c.429+9A>G	rs773277945
NM_006912.6(RIT1):c.430-18C>A	rs777450446
NM_006912.6(RIT1):c.430-5T>C	rs1571991209
NM_006912.6(RIT1):c.45C>T (p.Pro15=)	rs748838734
NM_006912.6(RIT1):c.486G>A (p.Glu162=)
NM_006912.6(RIT1):c.489A>G (p.Thr163=)	rs766952004
NM_006912.6(RIT1):c.48T>C (p.Ala16=)	rs1673577134
NM_006912.6(RIT1):c.492T>C (p.Ser164=)	rs2102581097
NM_006912.6(RIT1):c.498A>G (p.Ala166=)
NM_006912.6(RIT1):c.507C>T (p.Tyr169=)	rs2102581057
NM_006912.6(RIT1):c.519T>C (p.Asp173=)	rs1203053742
NM_006912.6(RIT1):c.531C>A (p.Ala177=)	rs2527171427
NM_006912.6(RIT1):c.552G>A (p.Arg184=)	rs1673290776
NM_006912.6(RIT1):c.570A>G (p.Val190=)	rs2527171305
NM_006912.6(RIT1):c.578T>C (p.Met193Thr)	rs1442986615
NM_006912.6(RIT1):c.588A>G (p.Lys196=)
NM_006912.6(RIT1):c.609A>G (p.Val203=)	rs142974413
NM_006912.6(RIT1):c.639G>A (p.Lys213=)	rs1673288442
NM_006912.6(RIT1):c.657T>C (p.Thr219=)
NM_006912.6(RIT1):c.659G>A (p.Ter220=)	rs2527170824
NM_006912.6(RIT1):c.72A>G (p.Leu24=)	rs770237120
NM_006912.6(RIT1):c.93T>C (p.Gly31=)	rs1202149849

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