ClinVar Miner

List of variants in gene SOS1 reported as benign for Noonan syndrome

Included ClinVar conditions (43):
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:
Total variants: 38
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HGVS dbSNP gnomAD frequency
NM_005633.4(SOS1):c.2791+53C>T rs7577088 0.94549
NM_005633.4(SOS1):c.2964+43C>A rs1454223 0.94284
NM_005633.4(SOS1):c.*2567T>A rs6704656 0.94064
NM_005633.4(SOS1):c.720+25C>G rs997344 0.92897
NM_005633.4(SOS1):c.*1844A>G rs10166395 0.80685
NM_005633.4(SOS1):c.*3918T>C rs1043793 0.79061
NM_005633.4(SOS1):c.*3539T>C rs1037495 0.79060
NM_005633.4(SOS1):c.*328A>G rs1059310 0.52005
NM_005633.4(SOS1):c.*805C>A rs1059313 0.14564
NM_005633.4(SOS1):c.*3724T>C rs11124658 0.04952
NM_005633.4(SOS1):c.195A>C (p.Arg65=) rs7609455 0.03809
NM_005633.4(SOS1):c.3081+32A>G rs6723430 0.02350
NM_005633.4(SOS1):c.1203-20T>C rs112906251 0.01058
NM_005633.4(SOS1):c.*3458A>C rs114232209 0.00673
NM_005633.4(SOS1):c.1074+5G>C rs145155424 0.00655
NM_005633.4(SOS1):c.*3569T>C rs115465194 0.00421
NM_005633.4(SOS1):c.345+15C>T rs75937422 0.00407
NM_005633.4(SOS1):c.3081+26G>A rs186106971 0.00284
NM_005633.4(SOS1):c.2122G>A (p.Ala708Thr) rs140811086 0.00280
NM_005633.4(SOS1):c.3081+13A>G rs189695571 0.00223
NM_005633.4(SOS1):c.1230G>A (p.Gln410=) rs141390073 0.00217
NM_005633.4(SOS1):c.213+16T>C rs150536159 0.00128
NM_005633.4(SOS1):c.*44T>C rs182657531 0.00060
NM_005633.4(SOS1):c.2371C>A (p.Leu791Ile) rs142004123 0.00053
NM_005633.4(SOS1):c.345+12_345+13dup rs397517167 0.00050
NM_005633.4(SOS1):c.1203-13T>A rs145166996 0.00049
NM_005633.4(SOS1):c.2964+17A>G rs201906525 0.00018
NM_005633.4(SOS1):c.214-10A>G rs371447614 0.00013
NM_005633.4(SOS1):c.510+9C>G rs553448375 0.00003
NM_005633.4(SOS1):c.3347-20T>G rs727505382 0.00001
NM_005633.3:c.213+15C>G
NM_005633.4(SOS1):c.*1333_*1336dup rs35969619
NM_005633.4(SOS1):c.2167+16del rs79984786
NM_005633.4(SOS1):c.2167+16dup rs79984786
NM_005633.4(SOS1):c.2511-9del rs727503436
NM_005633.4(SOS1):c.2674-22C>G rs61601281
NM_005633.4(SOS1):c.2792-50dup rs869215095
NM_005633.4(SOS1):c.2964+32T>G rs727505384

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