List of variants in gene SOS1 reported as likely pathogenic for Noonan syndrome

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Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

Total variants: 27

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HGVS	dbSNP	gnomAD frequency
NM_005633.4(SOS1):c.571G>A (p.Glu191Lys)	rs886041241	0.00001
NM_005633.4(SOS1):c.1009T>C (p.Tyr337His)	rs2124562542
NM_005633.4(SOS1):c.1132A>G (p.Thr378Ala)	rs397517146
NM_005633.4(SOS1):c.1293_1294delinsGA (p.Trp432Arg)	rs1572830693
NM_005633.4(SOS1):c.1300G>A (p.Gly434Arg)	rs397517148
NM_005633.4(SOS1):c.1310T>A (p.Ile437Asn)	rs397517150
NM_005633.4(SOS1):c.1310T>C (p.Ile437Thr)	rs397517150
NM_005633.4(SOS1):c.1310T>G (p.Ile437Ser)	rs397517150
NM_005633.4(SOS1):c.1430A>G (p.Gln477Arg)	rs730881044
NM_005633.4(SOS1):c.1477A>G (p.Lys493Glu)
NM_005633.4(SOS1):c.1653_1655del (p.Arg552del)	rs1572830219
NM_005633.4(SOS1):c.1708_1713del (p.Pro570_Ser571del)
NM_005633.4(SOS1):c.1867T>G (p.Phe623Val)	rs727505093
NM_005633.4(SOS1):c.2183A>T (p.Lys728Ile)	rs397517156
NM_005633.4(SOS1):c.2197A>T (p.Ile733Phe)	rs574088829
NM_005633.4(SOS1):c.2671G>A (p.Glu891Lys)	rs1553353452
NM_005633.4(SOS1):c.3022T>C (p.Tyr1008His)	rs397517163
NM_005633.4(SOS1):c.305C>G (p.Pro102Arg)	rs1553362937
NM_005633.4(SOS1):c.305C>T (p.Pro102Leu)
NM_005633.4(SOS1):c.322G>A (p.Glu108Lys)	rs397517164
NM_005633.4(SOS1):c.3248dup (p.Arg1084fs)	rs387906518
NM_005633.4(SOS1):c.335C>G (p.Pro112Arg)	rs397517166
NM_005633.4(SOS1):c.445G>A (p.Val149Ile)
NM_005633.4(SOS1):c.512T>C (p.Val171Ala)	rs397517174
NM_005633.4(SOS1):c.697A>T (p.Asn233Tyr)	rs1057519963
NM_005633.4(SOS1):c.805A>G (p.Met269Val)
NM_005633.4(SOS1):c.925G>A (p.Asp309Asn)	rs397517180

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