List of variants studied for Noonan syndrome by Clinical Genomics Laboratory, Washington University in St. Louis

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Total variants: 13

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HGVS	dbSNP	gnomAD frequency
NM_006767.4(LZTR1):c.410C>A (p.Thr137Asn)	rs146627447	0.00010
NM_006767.4(LZTR1):c.1855C>T (p.Arg619Cys)	rs373488966	0.00008
NM_006767.4(LZTR1):c.1183G>A (p.Val395Ile)	rs373591504	0.00004
NM_006767.4(LZTR1):c.1403G>A (p.Arg468His)	rs146427018	0.00004
NM_006767.4(LZTR1):c.1556G>A (p.Arg519Gln)	rs149502567	0.00003
NM_002834.5(PTPN11):c.1403C>T (p.Thr468Met)	rs121918457	0.00001
NM_006767.4(LZTR1):c.1260+1G>A	rs143868364	0.00001
NM_006767.4(LZTR1):c.485G>A (p.Trp162Ter)	rs1458120855	0.00001
NM_005633.4(SOS1):c.2167+5dup
NM_006767.4(LZTR1):c.1430C>G (p.Ala477Gly)
NM_006767.4(LZTR1):c.1720G>A (p.Val574Met)
NM_006767.4(LZTR1):c.1996T>G (p.Phe666Val)
NM_006939.4(SOS2):c.3305T>G (p.Val1102Gly)

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