ClinVar Miner

List of variants in gene SIM1 reported as uncertain significance for inherited obesity

Included ClinVar conditions (55):
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:
Total variants: 48
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HGVS dbSNP gnomAD frequency
NM_005068.3(SIM1):c.*1331T>C rs554615450 0.00148
NM_005068.3(SIM1):c.*15A>G rs143801416 0.00099
NM_005068.3(SIM1):c.*450T>C rs537039330 0.00089
NM_005068.3(SIM1):c.279C>T (p.Phe93=) rs145361258 0.00073
NM_005068.3(SIM1):c.2119G>C (p.Asp707His) rs74726213 0.00058
NM_005068.3(SIM1):c.1569T>C (p.His523=) rs138590764 0.00031
NM_005068.3(SIM1):c.*99G>A rs777887808 0.00016
NM_005068.3(SIM1):c.1865C>T (p.Ser622Phe) rs199543656 0.00012
NM_005068.3(SIM1):c.*1369C>A rs1188034610 0.00005
NM_005068.3(SIM1):c.*1125T>C rs758539915 0.00004
NM_005068.3(SIM1):c.2108G>A (p.Arg703Gln) rs376058205 0.00004
NM_005068.3(SIM1):c.624G>A (p.Val208=) rs753737612 0.00004
NM_005068.3(SIM1):c.*589G>A rs769730169 0.00003
NM_005068.3(SIM1):c.-58T>C rs886060898 0.00003
NM_005068.3(SIM1):c.1193C>T (p.Ser398Leu) rs1344055699 0.00003
NM_005068.3(SIM1):c.2194T>C (p.Leu732=) rs886060894 0.00003
NM_005068.3(SIM1):c.*1278C>T rs886060893 0.00002
NM_005068.3(SIM1):c.1147A>G (p.Arg383Gly) rs188821440 0.00002
NM_005068.3(SIM1):c.-181T>A rs886060899 0.00001
NM_005068.3(SIM1):c.1327A>G (p.Ser443Gly) rs755621081 0.00001
NM_005068.3(SIM1):c.1545C>T (p.His515=) rs758013576 0.00001
NM_005068.3(SIM1):c.1802A>G (p.Lys601Arg) rs781770499 0.00001
NM_005068.3(SIM1):c.2267A>G (p.Lys756Arg) rs762042848 0.00001
NM_005068.3(SIM1):c.226G>A (p.Val76Ile) rs756912317 0.00001
NM_005068.3(SIM1):c.289C>A (p.Pro97Thr) rs1217153562 0.00001
NM_005068.3(SIM1):c.628C>T (p.Leu210=) rs760422116 0.00001
NM_005068.3(SIM1):c.994C>T (p.Leu332Phe) rs1014536148 0.00001
NM_005068.3(SIM1):c.*128C>A rs1029968837
NM_005068.3(SIM1):c.*521A>G rs1770591929
NM_005068.3(SIM1):c.*56A>C rs1770603424
NM_005068.3(SIM1):c.*583G>C rs776246157
NM_005068.3(SIM1):c.*775G>A rs1049961951
NM_005068.3(SIM1):c.*873T>C rs1582597188
NM_005068.3(SIM1):c.1054C>T (p.Pro352Ser) rs3734354
NM_005068.3(SIM1):c.1125C>T (p.Leu375=) rs886060896
NM_005068.3(SIM1):c.1260G>C (p.Leu420=) rs781333048
NM_005068.3(SIM1):c.1352T>A (p.Leu451His) rs1770699139
NM_005068.3(SIM1):c.1452C>G (p.Ala484=) rs779506359
NM_005068.3(SIM1):c.2039C>T (p.Ser680Leu) rs149142065
NM_005068.3(SIM1):c.2111A>T (p.Gln704Leu) rs886060895
NM_005068.3(SIM1):c.2193C>T (p.Ser731=) rs747010066
NM_005068.3(SIM1):c.264G>A (p.Leu88=) rs374914727
NM_005068.3(SIM1):c.475T>C (p.Ser159Pro)
NM_005068.3(SIM1):c.804T>C (p.His268=) rs761256648
NM_005068.3(SIM1):c.804T>G (p.His268Gln) rs761256648
NM_005068.3(SIM1):c.816C>T (p.Cys272=) rs764549841
NM_005068.3(SIM1):c.817G>A (p.Asp273Asn) rs2114540224
NM_005068.3(SIM1):c.916T>C (p.Trp306Arg) rs1772382980

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