List of variants reported as uncertain significance for central nervous system malformation by Genetic Services Laboratory, University of Chicago

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Total variants: 15

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HGVS	dbSNP	gnomAD frequency
NM_025265.4(TSEN2):c.1389C>T (p.Asp463=)	rs75288720	0.00287
NM_002547.3(OPHN1):c.702+11A>C	rs375325266	0.00125
NM_207346.3(TSEN54):c.1114G>A (p.Val372Met)	rs200434678	0.00045
NM_025265.4(TSEN2):c.1013C>G (p.Thr338Arg)	rs145142315	0.00038
NM_025265.4(TSEN2):c.322G>T (p.Val108Phe)	rs202097247	0.00037
NM_001077446.4(TSEN34):c.468G>C (p.Ser156=)	rs376153530	0.00019
NM_025265.4(TSEN2):c.653C>T (p.Pro218Leu)	rs201214741	0.00011
NM_025265.4(TSEN2):c.608C>T (p.Thr203Ile)	rs35557378	0.00003
NM_207346.3(TSEN54):c.1181A>G (p.Gln394Arg)	rs560589823	0.00003
NM_207346.3(TSEN54):c.964C>G (p.Leu322Val)	rs587784480	0.00001
NM_001367721.1(CASK):c.1269C>T (p.Asn423=)	rs17315800
NM_001367721.1(CASK):c.2039G>C (p.Trp680Ser)	rs587783358
NM_001367721.1(CASK):c.617G>A (p.Gly206Asp)	rs587783367
NM_002547.3(OPHN1):c.2159-4C>T	rs587784233
NM_025265.4(TSEN2):c.1272T>C (p.Ile424=)	rs111535594

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