ClinVar Miner

Variants studied for chronic myelomonocytic leukemia

Included ClinVar conditions (8):
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign total
154 81 430 110 31 800

Gene and significance breakdown #

Total genes and gene combinations: 12
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Gene or gene combination pathogenic likely pathogenic uncertain significance likely benign benign total
NF1 98 68 351 83 1 600
PTPN11 39 7 29 18 14 105
CBL 4 4 42 5 15 67
LOC111811965, MIR4733HG, NF1 1 0 4 1 0 6
CBL, LOC130006895 0 0 1 3 1 5
KRAS 4 1 0 0 0 5
ARHGAP26 3 0 0 0 0 3
NRAS 3 0 0 0 0 3
ASXL1 1 0 1 0 0 2
CBL, FRA11B, LOC130006894 0 0 2 0 0 2
ETV6, FLT3 0 1 0 0 0 1
EVI2A, NF1 1 0 0 0 0 1

Submitter and significance breakdown #

Total submitters: 15
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Submitter pathogenic likely pathogenic uncertain significance likely benign benign total
Fulgent Genetics, Fulgent Genetics 59 17 210 107 4 397
Baylor Genetics 75 57 228 0 0 360
KCCC/NGS Laboratory, Kuwait Cancer Control Center 1 0 0 3 28 32
Center for Genomics, Ann and Robert H. Lurie Children's Hospital of Chicago 16 1 4 0 1 22
OMIM 16 0 0 0 0 16
Laboratory for Molecular Medicine, Mass General Brigham Personalized Medicine 15 1 0 0 0 16
NIHR Bioresource Rare Diseases, University of Cambridge 2 3 0 0 0 5
Molecular Genetics Lab, CHRU Brest 2 1 0 0 0 3
Institute for Genomic Medicine (IGM) Clinical Laboratory, Nationwide Children's Hospital 1 0 0 0 0 1
Mendelics 0 1 0 0 0 1
Mayo Clinic Laboratories, Mayo Clinic 1 0 0 0 0 1
Genomic Research Center, Shahid Beheshti University of Medical Sciences 0 0 1 0 0 1
Genetics and Molecular Pathology, SA Pathology 0 0 1 0 0 1
Knight Cancer Institute, Oregon Health and Science University 0 1 0 0 0 1
Johns Hopkins Genomics, Johns Hopkins University 0 0 1 0 0 1

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